Titanium dioxide nanotubes enhance bone bonding in vivo
Implant topography is critical to the clinical Success of bone-anchored implants, yet little is known how nano-modified implant topography affects osseointegration. We investigate the in vivo bone bonding of two titanium implant surface: titanium dioxide (TiO2) nanotubes and TiO2 gritblasted surfaces. In previous in vitro studies, the topography of the TiO2 nanotubes improved osteoblast proliferat