Objectives. COMP is a regulator of assembly and maintenance of the fibrillar collagen I and II networks. Serum COMP reflects skin fibrosis in SSc. The purpose of this study was to examine whether serum COMP reflects fibrotic lung involvement in SSc patients and to study if serum COMP predicts mortality.Methods. Three overlapping cohorts of 244 SSc patients were studied. Two hundred and eighteen pa

Adsorbed organic compounds modify the properties of environmental interfaces with potential implications for many Earth system processes. Here, we describe experimental studies of water interactions with acetic acid (AcOH) layers on ice and graphite surfaces at temperatures from 186 to 200 K. Hyperthermal D2O water molecules are efficiently trapped on all of the investigated surfaces, with only a

Polysaccharide-K (PSK, Krestin) is one of the most commonly used medicinal mushroom extracts with a long history as an additive in cancer therapy in Asia, especially in Japan. PSK has a documented anti-tumor activity both in vitro and in vitro, in various types of cancers, including colorectal, gastric, breast, liver, pancreatic, and lung cancer. Despite PSK having been studied for about 40 years

We describe a new liquid-target system for low-debris laser-plasma soft x-ray sources. The system is based on a microscopic liquid jet and is experimentally evaluated for 0.7-1 keV proximity lithography and water-window x-ray microscopy applications. Compared to an existing liquid-droplet target, this target system has the same low debris emission, high x-ray photon flux, and narrow spectral bandw

To study cell-free fetal hemoglobin (HbF) and the heme-scavenger α1- microglobulin (A1M) in patients with manifest preeclampsia (PE) and how these proteins performed as possible biomarkers of PE and adverse maternal and fetal outcomes.

Based on a systematic registration of written sources and all the archaeological material. Out of 11 church institutions 6 are known from archaeological investigations. Discussion on the datings, architecture, social context and economical hinterland of the institutions. Extensive list of literature and sources.The text is an edited version of a cand phil-dissertation from the University of Aarhus

OBJECTIVE: To test the performance of CK5/6 for the differentiation between mesothelioma, adenocarcinoma and benign mesothelia/proliferations in effusion cytology. STUDY DESIGN: CKS/6 immunocytochemistry was applied to ethanol-fixed cytospin preparations from 74 benign and malignant effusions. RESULTS: Reactivity was seen in 7 of 8 mesotheliomas and in 9 of 11 benign mesothelial proliferations but

Att delta i en anhörigförening kan betraktas som ett sätt att bryta mot sjukvårdens individualiserande och problematiserande syn på anhöriga och normalisera en alternativ anhörigidentitet. Gemenskapen inom föreningen spelar då en avgörande roll; den ”besvarar” och motarbetar individualiseringen samt upprätthåller en växling mellan glädje och bekymmer som motarbetar problematiseringen.

Abstract is not available

New dual antiplatelet therapies (DAPTs) have been introduced in clinical practice for patients with acute coronary syndrome (ACS). This nationwide study investigated DAPT patterns over time and patient characteristics associated with the various treatments in a population with ACS.

While the common lymphoid progenitor compartment was originally thought to be a rather homogenous cell population, it has become increasingly clear that this compartment is highly heterogeneous both with regard to phenotypic and functional features. The exploration of this cellular complexity has generated novel molecular insights into regulatory events in lymphoid lineage restriction and provided

Aims: To illuminate patients' experiences of being cared for and nurses' experiences of caring for patients in a multiple-bed hospital room. Background: Many patients and healthcare personnel seem to prefer single-bed hospital rooms. However, certain advantages of multiple-bed hospital rooms (MBRs) have also been described. Method: Eight men and eight women being cared for in a multiple-bedroom

Research study was conducted from January to May, 2002 in residential areas along the Palosi Drain, Peshawar. Main objective of the study was to evaluate water quality of shallow and deep wells in the vicinity of Palosi Drain. For this purpose, 20 water samples were taken 13 from shallow wells, 3 from deep wells and 4 from wastewater in the Palosi Drain. Water samples were analyzed for heavy metal