Apolipoprotein M (apoM) is predominantly associated with HDL. In this study, it was investigated whether apoM's uncleaved signal peptide is necessary for the protein's ability to associate with lipoproteins. ApoM with a cleavable signal peptide, Q22A, was expressed, together with wild-type apoM, in HEK293 cells. On size-exclusion chromatography, the elution profile of wild-type apoM was similar to

The Lake Poopo basin, located on the Bolivian Altiplano, is extremely vulnerable to environmental degradation. The basin displays extreme spatial and temporal variations of water resources and rapidly decreasing water quality due to anthropogenic and natural pollution. The region’s population lives in extreme poverty, and the authorities’ efforts to manage the water resources efficiently have been

Pragma-dialectical argumentation theory has received criticism from epistemological argumentation theorists. While the former emphasizes argumentation as aimed at resolving differences of opinion through adequate procedures, the latter emphasizes that argumentation is aimed at reaching a justified conclusion of the argumentation. In this paper pragma-dialectics is analyzed and two objections consi

In this paper, we propose a preemptive test scheduling technique (a test can be interrupted and later resumed) for core-based systems with the objective to minimize the test application time. We make use of reconfigurable core test wrappers in order to increase the flexibility in the scheduling process. The advantage with such a wrapper is that it is not limited to a single TAM (test access mechan

OBJECTIVES: Acute superior mesenteric artery (SMA) occlusion can be diagnosed in an early phase by computed tomography (CT) angiography, which is also a prerequisite for endovascular intervention. However, the issue of development of postoperative permanent renal failure due to contrast-induced nephropathy has not been evaluated. DESIGN: Retrospective MATERIALS: A total of 55 patients with acute S

This article aims to contribute to the understanding concerning the introduction of crisis psychotherapy in the 1970s in psychiatric clinics in Sweden. The article discusses how this psychotherapy became central in the work of the clinics in supporting patients to well-being and inner growth. The ambition was that patients in an acute crisis-situation would be offered care immediately, aiming at a

BACKGROUND: IdeS, a proteinase from Streptococcus pyogenes, cleaves immunoglobulin (Ig)G antibodies with a unique degree of specificity. Pathogenic IgG antibodies constitute an important clinical problem contributing to the pathogenesis of a number of autoimmune conditions and acute transplant rejection. To be able to effectively remove such antibodies is therefore an important clinical challenge.

The author extends the ideas of Bardyszewski and Hedin (1987) to treat EXAFS. He summarises the theory, adds new viewpoints and extends the theory.

Kulturartikel om den europeiska filmens katastrofala ekonomi och misslyckade försök att konkurrera mot amerikansk filmindustri med konstfilmsproduktion.

We have a very limited knowledge about how the confinement mechanism works in processes like $\epea\epe\ra\epq\epqa\ggn\ldots\ggn$, when there are identical colour charges. In this case the partons can be colour connected by a string or a cluster chain in several different ways. We do not know if in such a situation Nature chooses a particular configuration at random, or if some configuration is d

This short report draws attention to an interesting kind of configuration in the lexicon that seems to have escaped theoretical or systematic descriptive attention. These configurations, which we dub SEMPLATES, consist of an abstract structure or template, which is recurrently instantiated in a number of lexical sets, typically of different form classes. A number of examples from different languag