We have used suramin and brefeldin A to investigate the nature of a heparan sulphate proteoglycan that appears to recycle from the cell surface to intracellular compartments which synthesize new heparan sulphate chains. Suramin, which would block internalization and deglycanation of a putative recycling cell surface proteoglycan, markedly increases the yield of a membrane-bound proteoglycan with a

The protochlorophyll(ide) present in primary roots of dark-grown corn (Zea mays) seedlings has an in vivo absorption maximum at 634 nm. Red light converts the pigment to chlorophyll(ide) a with an absorption maximum at 675 nm.

In acetonitrile, polyisoprene-b-poly(methyl methacrylate) (PI−PMMA) diblock copolymers form starlike micelles with a dense core of the insoluble PI blocks and a soft solvent-swollen corona of the soluble PMMA blocks. Static and dynamic light scattering experiments in combination with viscosity measurements show that these micelles behave hydrodynamically as hard spheres. The block copolymers are l

This paper is an attempt to further our understanding of mechanisms conceived of as ontologically separable from laws. What opportunities are there for a mechanistic perspective to be independent of, or even more fundamental than, a law perspective? Advocates of the mechanistic view often play with the possibility of internal and external reliability, or with the paralleling possibilities of enfor

The catalytic cracking of ethanol on clean and oxygen precovered Rh(1 1 1) surfaces has been studied by a combination of synchrotron based high-resolution core level spectroscopy and surface infrared spectroscopy. On the clean surface the decomposition of ethanol occurs without any formation of atomic oxygen. The presence of oxygen on the surface changes the reactivity significantly and previous t

Uninformed buyers' demand for statistical screening between privately informed sellers is studied in a fixed price market. A single buyer will screen more extensively than would two or more buyers, since in the latter case buyers realize that sellers will be attracted to buyers with the most favorable screening policy (i.e., not to screen at all). This result is robust to some but not all types of

What makes a headmaster successful? And what does a successful headmaster do? This article presents some results from a research project – Successful school leadership in different school cultures – that aims to provide answers to these questions. The results derive from interviews, questionnaires, observations and pupils’ essays, and comprise the criteria by which different parties involved in sc

The article considers various ethical issues in the supervision of doctoral students. Narratives collected at seven Swedish universities describing problematic situations in supervision were analyzed against the background of basic ethical principles, professional ethics of European psychologists, a list of critical incidents from the US, and a code of conduct for supervisors at Oslo University. A

Objective To describe and classify endosonographic obstetric sphincter defects at 1 week, 3 months and 1 year after primary repair, and to relate the endosonographic results to anal sphincter pressure and to symptoms of anal incontinence over time. Methods Forty-one women who had suffered a third- or fourth-degree perineal tear at delivery underwent anal endosonography and anal manometry 1 week,

The effect of warmer climate on the depletion of snow-covered area has been evaluated for the Satluj River basin located in the western Himalayan region in India. Snowmelt runoff contributes substantially to the annual streamflow of this river. In order to study the impact of three warming scenarios (T+1, T+2 and T+3degreesC), more than 160 new snow depletion curves were prepared for different ele

Fifty eight enterococcal isolates from wild herbivores were tested for their antibiotic sensitivity pattern and lectin-like binding of extracellular matrix (ECM) and serum proteins. Kanamycin resistance was very frequent; many multiresistant strains were also isolated. All isolates were sensitive to rifampicin. Resistance to gentamicin, novobiocin, and tetracycline was widely distributed in the mi