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Elucidating the Bulk Morphology of Cellulose-Based Conducting Aerogels with X-Ray Microtomography

Conducting cellulose composites are promising sustainable functional materials that have found application in energy devices, sensing and water purification. Herein, conducting aerogels are fabricated based on nanofibrillated cellulose and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate, using the ice templating technique, and their bulk morphology is characterized with X-ray microtomograph

Genetic prediction of 33 blood group phenotypes using an existing genotype dataset

Background: Accurate blood type data are essential for blood bank management, but due to costs, few of 43 blood group systems are routinely determined in Danish blood banks. However, a more comprehensive dataset of blood types is useful in scenarios such as rare blood type allocation. We aimed to investigate the viability and accuracy of predicting blood types by leveraging an existing dataset of

Differential encoding of temporally evolving color patterns across nearby V1 neurons

Whereas studies of the V1 cortex have focused mainly on neural line orientation preference, color inputs are also known to have a strong presence among these neurons. Individual neurons typically respond to multiple colors and nearby neurons have different combinations of preferred color inputs. However, the computations performed by V1 neurons on such color inputs have not been extensively studie

Body-Focused Repetitive Behavior Disorders in Children and Adolescents : Clinical Characteristics and Treatment Outcomes in a Naturalistic Setting

Body-focused repetitive behavior disorders, including trichotillomania (hair-pulling disorder) and excoriation (skin picking) disorder, typically emerge in early adolescence, but little is known about the clinical characteristics and treatment outcomes of these disorders in young people, particularly in real-world clinical settings. Participants were 63 children and adolescents (51 girls; age rang

Who polarizes parliament? Partisan hostility in Norwegian legislative debates

In many democratic societies, research has identified an increase in animosity between supporters of different political parties. While this phenomenon has been extensively examined among the general public, less research has explored the role of political elites in contributing to partisan hostility. This study aims to fill this research gap by analyzing instances where members of parliament (MPs

Small Extracellular Vesicles from adipose-derived stem cells suppress cell proliferation by delivering the let-7 family of microRNAs in ovarian cancer

Introduction: Ovarian cancer is the leading cause of death among women with gynecological cancer, and novel treatment options are urgently needed. Extracellular vesicles (EVs), including exosomes, may be one of the most promising therapeutic tools for various diseases. In this study, we aimed to investigate the therapeutic effects of adipose-derived stem cell-derived EVs (ADSC-EVs) on ovarian canc

Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid

Congenital diaphragmatic hernia (CDH) is a severe birth defect frequently associated with pulmonary hypoplasia, pulmonary hypertension, and heart failure. Since amniotic fluid comprises proteins of both fetal and maternal origin, its analysis could provide insights on mechanisms underlying CDH and provide biomarkers for early diagnosis, severity of pulmonary changes and treatment response. The stu

Compliance with National and International Guidelines in the Treatment of Nonmotor Symptoms in Late-Stage Parkinson's Disease

Background. National as well as international Parkinson's disease (PD) treatment guidelines are available to guide clinicians. Previous research has shown that nonmotor symptoms (NMS) are pronounced in late-stage PD and has suggested that current treatment is insufficient and could be improved. Objectives. The aim of this study was to investigate to which degree the national and international trea

How dawn turned into dusk: Scoping and closing possible nuclear futures after the Cold War

How was the scope of nuclear weapons policy change immediately after the Cold War determined? Nuclear learning and worst-case thinking are common but not satisfactory answers. On the basis of primary sources in multiple languages, we posit that a particular temporalization of nuclear events in the beginning of the 1990s took place: nonproliferation timescaping. The Iraqi case of opaque proliferati

Strategies to increase fathers’ engagement in child protection investigations due to domestic partner abuse in Sweden

Social workers often fail to engage fathers in child protection investigations (CPIs), especially when they involve domestic abuse (DA) by fathers. The aim of this study is to examine the strategies used by social workers to achieve cooperation with fathers in CPIs that involve the father being suspected of DA against the child's mother. With the use of qualitative methods, we conducted 31 semi-st

On the interactions between RNA and titrateable lipid layers : implications for RNA delivery with lipid nanoparticles

Characterising the interaction between cationic ionisable lipids (CIL) and nucleic acids (NAs) is key to understanding the process of RNA lipid nanoparticle (LNP) formation and release of NAs from LNPs. Here, we have used different surface techniques to reveal the effect of pH and NA type on the interaction with a model system of DOPC and the CIL DLin-MC3-DMA (MC3). At only 5% MC3, differences in

Minimax Linear Optimal Control of Positive Systems

We present a novel class of minimax optimal control problems with positive dynamics, linear objective function and homogeneous constraints. The proposed problem class can be analyzed with dynamic programming and an explicit solution to the Bellman equation can be obtained, revealing that the optimal control policy (among all possible policies) is linear. This policy can in turn be computed through