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β ‐amyloid accumulation was linked to significant cognitive dysfunction in cognitively unimpaired participants with subthreshold levels of β ‐amyloid in multiple measures of memory (Logical Memory Delayed Recall, P = 0.03; Free and Cued Selective Reminding Test, P < 0.001), the Preclinical Alzheimer’s Cognitive Composite (P = 0.01), and was marginally associated with decreased executive function (

https://www.lupop.lu.se/article/a4-study-b-amyloid-and-cognition-4432-cognitively-unimpaired-adults - 2025-10-27

A large proportion of patients (29%) continued to experience high distress (>3 according to the Distress Thermometer) even after treatment was completed. Patients experienced several problems after treatment had ended such as fatigue (44%), sleep problems (34%), worries (31%), pain (31%), tingling in hands and feet (31%) and problems with memory/concentration (30%). Patients with financial/insuran

https://www.lupop.lu.se/article/cross-sectional-study-distress-cancer-response - 2025-10-27

Are people more likely to become more politically active through social media when they observe that their friends are active? Previous research has shown that an individual's likelihood of engaging politically is influenced by observations of how friends act through social media, but relatively little is known about how such social influence through social media interacts with personality feature

https://www.lupop.lu.se/article/social-network-how-friends-online-behavior-and-belongingness-needs-influence-political-activity - 2025-10-27

In an attempt to learn more about the behavior and evolution of various forms of CM and SM, the European Competence Network on Mastocytosis (ECNM) initiated a mastocytosis registry in 2012. In this article, the set up and start phase of this registry are described New publication in The Journal of Allergy and Clinical Immunology: In Practice

https://www.lupop.lu.se/article/data-registry-european-competence-network-mastocytosis-ecnm-set-projects-and-perspectives-0 - 2025-10-27

There were 309 cases of NIHF at birth corresponding to an incidence of 1.6 per 10 000, lower than in previous studies. NIHF was more frequent in mothers aged ≥35 years and with a history of stillbirth. Preterm delivery occurred in 77.7% in the NIHF group, including 31.7% before 32 weeks of gestation. Multiple births and Caesarean sections were reported more frequent in the NIHF group. NIHF was ass

https://www.lupop.lu.se/article/non-immune-hydrops-fetalis-was-rare-sweden-during-1997-2015-cases-were-associated-complications-and - 2025-10-27

A nationwide study of individuals residing in Sweden. Urolithiasis was defined as having at least one registered diagnosis of urolithiasis in the Swedish National Patient Register between January 1, 1998 and December 31, 2015. Cox regression analysis was used to estimate the relative risk (hazard ratios (HR) with 95% confidence intervals (CI)) of incident urolithiasis compared to individuals with

https://www.lupop.lu.se/article/urolithiasis-second-generation-immigrant-children-younger-18-years-age-sweden - 2025-10-27

In order to provide responsible access to health data by reconciling benefits of data sharing with privacy rights and ethical and regulatory requirements, Findable, Accessible, Interoperable and Reusable (FAIR) metadata should be developed. According to the H2020 Program Guidelines on FAIR Data, data should be “as open as possible and as closed as necessary”, “open” in order to foster the reusabil

https://www.lupop.lu.se/article/fair-open-possible-closed-necessary-show-all-authors - 2025-10-27

Clinical and histological parameters were obtained from the Swedish Melanoma Registry for patients diagnosed with thin CMM between 1990 and 2017. Patients were followed until the end of 2017. MSS as well as CMSS for different thickness groups were calculated using the Kaplan–Meier method and Cox regression analyses were used to calculate for survival differences between thickness groups. New publi

https://www.lupop.lu.se/article/survival-31-670-patients-thin-melanomas-swedish-population-based-study - 2025-10-27

Communication ability and method were related to each other and to age, gross motor function, and manual ability. Aided communication methods were more frequently used among older children. The more functional the communication was, the less use of unaided communication occurred. Different communication methods were used across all Communication Function Classification System (CFCS) levels. Speech

https://www.lupop.lu.se/article/communication-ability-and-communication-methods-children-cerebral-palsy - 2025-10-27

Parents of children participating in screening studies may experience increased levels of anxiety. The aim of this study was to assess parental anxiety levels after 5 years of participation in the Diabetes Prediction in Skåne study. Associations between parental anxiety about their child developing type 1 diabetes and clinical, demographic, and immunological factors were analyzed. New publication

https://www.lupop.lu.se/article/parental-anxiety-after-5-years-participation-longitudinal-study-children-high-risk-type-1-diabetes - 2025-10-27

The Quality of Dyadic Relationships is a self‐assessment scale used to evaluate various aspects of relationship quality. Psychometric evaluation by the developers of the instrument has led to a nontested amended version. Further psychometric testing is thus warranted, and the aim of this study was to evaluate homogeneity, construct validity (in terms of concurrent, discriminant and known‐groups va

https://www.lupop.lu.se/article/psychometric-evaluation-swedish-quality-dyadic-relationships-scale-homogeneity-and-construct - 2025-10-27

Provar att visa en nyhet

https://www.cgbkansli.lu.se/artikel/ny-webbplats-cgb-kansli - 2025-10-27

Through her work, Professor Cenci Nilsson has developed preclinical models mimicking the symptoms of Parkinson’s disease and L-DOPA-induced dyskinesia, exploiting these models to discover disease mechanisms and new therapeutic approaches. With this motivation, MultiPark’s coordinator was awarded the 2022 Bengt Falck Prize in Neuroscience. In this extensive interview, Angela Cenci Nilsson shares he

https://www.multipark.lu.se/article/multiparks-coordinator-awarded-bengt-falck-prize-neuroscience - 2025-10-27

Imaging methods are valuable tools for understanding neurodegenerative diseases and monitoring the therapeutic effects of new treatments. That is why MultiPark researchers with expertise in clinical imaging gather across research groups. Clinical imaging methods is a new special interest group (SIG) addressing scientific and technological needs to apply these methods in research. Nicola Spotorno t

https://www.multipark.lu.se/article/clinical-imaging-methods-special-interest-group - 2025-10-27

People with Parkinson´s disease (PD) often develop abnormal involuntary movements (dyskinesias) during the course of their treatment with dopaminomimetic drugs.  In this new collaborative project, Angela Cenci Nilsson (Lund), Mattias Rickhag (Copenhagen) and Gilad Silberberg (Stockholm) will unravel the connections between dyskinesia and changes in the way the cerebral cortex and the striatum proc

https://www.multipark.lu.se/article/new-collaborative-project-tackles-previously-unknown-mechanisms-parkinsons-dyskinesias - 2025-10-27

Martino Avallone spent the past four years developing tools for mapping gene expression and proteins in the brain to investigate basic biological questions and to elucidate the molecular mysteries contributing to Parkinson’s disease. On 29 September, he defends his thesis work done in the Molecular Neuromodulation research group. Here, he explains the impact these tools will hopefully have in scie

https://www.multipark.lu.se/article/genetic-tools-studying-parkinsons-disease-phd-interview-martino-avallone - 2025-10-27

Megg Garcia-Ryde’s thesis sheds light on the early pathological processes in Alzheimer’s disease and the interplay between neurons and microglia as the disease evolves. October 10, she defends her thesis. Now, she gives her perspectives from a close collaboration between two of MultiPark’s experimental research groups and how she brings together the expertise of both groups. Tell us about your res

https://www.multipark.lu.se/article/neuroimmune-crosstalk-early-alzheimers-disease-phd-interview-megg-garcia-ryde - 2025-10-27

In today's scientific world, microscopic images have become a powerful resource for research. With access to advanced microscopes, researchers can now create unique images of structures and objects. Beautiful and captivating images that can also convey complex context to a wider audience. Microscopic images offer a clear advantage over purely quantitative measurements: they allow us to see the str

https://www.multipark.lu.se/article/making-invisible-visible-magic-microscopic-images - 2025-10-27

Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group in Lund is discovering. "We have observed that an enzyme in cerebrospinal fluid and in blood is a useful marker for identifying all types of Parkinson's-related diseases with high accuracy," says Oskar Hansson, who led the study. The marker in quest

https://www.multipark.lu.se/article/new-blood-marker-can-identify-parkinsonian-diseases - 2025-10-27

Jana Rájová’s research turns light on gene expression in different parts of the brain affected by Parkinson’s disease. October 23, she defends her thesis in the Molecular Neuromodulation research group. In this interview, she tells about how it has been to combine wet and dry lab work and about the technical advances in the field. Tell us about your research! “Throughout my Ph.D. journey, my resea

https://www.multipark.lu.se/article/gene-expression-parkinsons-disease-phd-interview-jana-rajova - 2025-10-27