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The use of negative control outcomes in Mendelian randomization to detect potential population stratification

A key assumption of Mendelian randomization (MR) analysis is that there is no association between the genetic variants used as instruments and the outcome other than through the exposure of interest. One way in which this assumption can be violated is through population stratification, which can introduce confounding of the relationship between the genetic variants and the outcome and so induce an

https://www.lupop.lu.se/article/use-negative-control-outcomes-mendelian-randomization-detect-potential-population-stratification - 2025-11-23

SWE-REG Autumn Meeting 2021: How to conduct successful interdisciplinary research

The Swedish Network for Register-Based Research (SWE-REG) is a collaboration between eight research nodes – seven research environments and a graduate school in register-based research. The network strives to use register-based data for research that may benefit people’s health and well-being. Read more, and register at https://swe-reg.se/

https://www.lupop.lu.se/article/swe-reg-autumn-meeting-2021-how-conduct-successful-interdisciplinary-research - 2025-11-23

Job opportunity: Doctoral student in Medical Science - Environmental risk factors for IBD

Project title: Early-life environmental risk factors for inflammatory bowel disease: A Nordic birth cohort study Project: Inflammatory bowel disease (IBD) is a chronic, debilitating immune-mediated disease with a typical onset in childhood and young adulthood. After a rising incidence over the past decades, it now affects 0.5% of Western populations, and is an emerging disease globally. There is a

https://www.lupop.lu.se/article/job-opportunity-doctoral-student-medical-science-environmental-risk-factors-ibd - 2025-11-23

New LU-policy for open access

Open access (OA) means that research results are published freely available to everyone on the web. The university's open access policy is a way of contributing to open access being the norm for research information. There are several ways for researchers to make publications freely available. Read more at https://www.ub.lu.se/en/publish/open-access

https://www.lupop.lu.se/article/new-lu-policy-open-access - 2025-11-23

Vetenskapsrådets samordningsuppdrag om öppen tillgång till forskningsdata – delredovisning

Vetenskapsrådet har i uppdrag av regeringen att främja och samordna det nationella arbetet med att införa öppen tillgång till forskningsdata. Denna rapport är en delredovisning av Vetenskapsrådets uppdrag och beskriver arbetet och insatserna som genomförts, samt ger en internationell utblick. Ladda ner rapporten på https://www.vr.se/analys/rapporter/vara-rapporter/2021-10-06-vetenskaps…

https://www.lupop.lu.se/article/vetenskapsradets-samordningsuppdrag-om-oppen-tillgang-till-forskningsdata-delredovisning - 2025-11-23

Nu kan du anmäla informationssäkerhetsincidenter!

Har du tappat bort ett USB-minne med känsliga uppgifter? Eller har du sett någon stryka omkring i universitetets lokaler med en möjlig avsikt att tillskansa sig värdefull information? Det finns gott om exempel på tänkbara informationssäkerhetsincidenter som måste anmälas. En informationssäkerhetsincident är ”en oönskad händelse med negativa konsekvenser som handlar om säkerheten för information".

https://www.lupop.lu.se/article/nu-kan-du-anmala-informationssakerhetsincidenter - 2025-11-23

Ny studie från Region Skåne: Återfall av Clostridium difficle

Vid verksamhetsområdet infektionssjukdomar på Skånes universitetssjukhus planeras en studie kring återfall av Clostridium difficile (nyligen namnbyte till Clodstridoides difficile). Studien ska utreda vilka faktorer som kan vara avgörande för att få fler återfall. Läs mer på https://www.lupop.lu.se/aterfall-av-clostridium-difficle

https://www.lupop.lu.se/article/ny-studie-fran-region-skane-aterfall-av-clostridium-difficle - 2025-11-23

Strength in causality: discerning causal mechanisms in the sufficient cause model

In this article, we discuss how to discern the causal mechanisms of interest in the sufficient cause model, which pays closer attention to the relationship between the sufficient cause model and the Bradford Hill viewpoints. Read the paper at https://link.springer.com/article/10.1007%2Fs10654-021-00798-6

https://www.lupop.lu.se/article/strength-causality-discerning-causal-mechanisms-sufficient-cause-model - 2025-11-23

Extension of Mendelian Randomization to Identify Earliest Manifestations of Alzheimer Disease

In an extension of Mendelian randomization, we leveraged variation in genetic risk for late-onset AD risk to estimate the causal effect of AD on BMI and the earliest ages at which AD-related weight loss (or lower BMI as a proxy) occurs. Read the paper at https://academic.oup.com/aje/article/190/10/2163/6222073

https://www.lupop.lu.se/article/extension-mendelian-randomization-identify-earliest-manifestations-alzheimer-disease - 2025-11-23