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The Danish randomized trial studying the effect of mask recommendation (DANMASK-19) was widely discussed in the media. We aimed to analyze this trial from a causal inference perspective. Read the paper at https://academic.oup.com/aje/article/190/10/2231/6279406
https://www.lupop.lu.se/article/use-nonparametric-bounds-causal-effects-null-randomized-trials - 2025-11-17
In this article, we illustrate that careful scrutiny based on the conventional sufficient cause model yields further insights into the concept of agonism in a more biologic sense. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/11000/Marginal_Sufficient…
https://www.lupop.lu.se/article/marginal-sufficient-component-cause-model-emerging-causal-model-merits - 2025-11-17
In an extension of Mendelian randomization, we leveraged variation in genetic risk for late-onset AD risk to estimate the causal effect of AD on BMI and the earliest ages at which AD-related weight loss (or lower BMI as a proxy) occurs. Read the paper at https://academic.oup.com/aje/article/190/10/2163/6222073
https://www.lupop.lu.se/article/extension-mendelian-randomization-identify-earliest-manifestations-alzheimer-disease - 2025-11-17
Adjusting for epidemic curves based on surveillance data is necessary if estimates of missed cases and the effective reproduction number play a role in management of the COVID-19 pandemic. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/11000/Effect_of_Adjustmen…
We developed and validated a synthetic cohort approach to examine numbers of cardiovascular risk factors (CRFs) and adverse clinical events, including incident cardiovascular disease and all-cause mortality, across the life span from ages 20 years to 90 years. Read the paper at https://academic.oup.com/aje/article/190/10/2208/6274861
Smart card data (SCD) allow analyzing mobility at a fine level of detail, despite the remaining challenges such as identifying trip purpose. The use of the SCD may improve the understanding of transit users' travel patterns from precarious settlements areas, where the residents have historically limited access to opportunities and are usually underrepresented in surveys. Read the paper at https://
Nationwide healthcare registries are potential important real-world data (RWD) sources for assessing drug effectiveness in oncology. However, it is unclear whether registry-derived RWD are suitable for clinical development. Read the paper at https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt.2424
Despite progress toward curtailing opioid prescribing, physicians are often slow to adopt new prescribing practices. Using the Abdominal Core Health Quality Collaborative (ACHQC), we aimed to demonstrate the ability of a national, disease-specific, personalized registry to impact opioid prescribing. Read the paper at https://link.springer.com/content/pdf/10.1007/s10029-021-02495-5.pdf
The overall accuracy of data held in the New Zealand Trauma Registry (NZTR) is suitable for quality improvement and benchmarking purposes, but more work is needed to improve the accuracy of individual cases, particularly those with head/neck and chest injury. Read the paper at https://journals.sagepub.com/doi/full/10.1177/14604086211041877
https://www.lupop.lu.se/article/accuracy-injury-coding-trauma-registry - 2025-11-17
A well-managed institutional arthroplasty registry, including structured clinical and radiological follow-up assessments, offers the opportunity for high-quality long-term patient and arthroplasty outcome analysis. Such data are not only helpful for analyzing patient outcome and implant survival, but will be increasingly important to justify our daily clinical practice against different stakeholde
https://www.lupop.lu.se/article/establishing-institutional-reverse-total-shoulder-arthroplasty-registry - 2025-11-17
We developed standardized QA processes for training, certification and supervision of the MNHR, a multisite research registry. It is expected that these activities, together with ongoing QA processes, will help to further optimize data quality for this protocol. Read the paper at https://reproductive-health-journal.biomedcentral.com/articles/10.1186/…
This registry will assess outcomes in patients with genetically confirmed SMA and provide information on the effectiveness and long-term safety of approved and emerging treatments. Read the paper at https://content.iospress.com/articles/journal-of-neuromuscular-diseases…
Our findings suggest that in studies of air pollution and cardiometabolic disease, which use an adjustment strategy with a broad range of register-based socioeconomic variables, there is no effect on risk estimates from subsequent lifestyle adjustment. Read the paper at https://www.sciencedirect.com/science/article/pii/S0013935121011816
The registration committee for esophageal cancer in the Japan Esophageal Society (JES) has collected the patients' characteristics, treatment, and outcomes annually. Read the paper at https://link.springer.com/article/10.1007%2Fs10388-021-00879-1
https://www.lupop.lu.se/article/comprehensive-registry-esophageal-cancer-japan-2014 - 2025-11-17
Stroke is the second most common cause of adult death in Africa. This study reports the demographics, stroke types, stroke care and hospital outcomes for stroke in Freetown, Sierra Leone. Read the paper at https://www.frontiersin.org/articles/10.3389/fneur.2021.712060/full
Among THR patients value sets based on the same method and perspective, a direct transfer of results across countries could be meaningful. In cases of differences in methods and perspectives among value sets, transfer of value sets across settings would have to consider conversion through crosswalk. Read the paper at https://www.mdpi.com/2077-0383/10/18/4205
Assortativity is the tendency of individuals connected in a network to share traits and behaviors. Through simulations, we demonstrated the potential for bias resulting from assortativity by vaccination, where vaccinated individuals are more likely to be connected with other vaccinated individuals. Read the paper at https://academic.oup.com/aje/article/190/11/2442/6292355
Here, we outline 3 federal, publicly available data sources for estimating the number of people experiencing homelessness in the United States. We describe the appropriate uses and limitations of each data source in the context of infectious disease epidemiology. Read the paper at https://academic.oup.com/aje/article/190/11/2432/6159692
This review provides important insights about the benefits and challenges of using routinely-collected, population-based linked databases for conducting population-based multigenerational health research, and identifies opportunities for future research within and across the data-intensive environments at these six sites. Read the paper at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530190/
The senior lecturer in epidemiology with a focus on research must, in addition to conducting high-quality epidemiological research primarily concerning the etiology of allergic diseases and hypersensitivity, also have a leading role in environmental health risk assessment and teach epidemiology. Read more, and apply, at https://ki.varbi.com/en/what:job/jobID:371203/
