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Researchers at Lund University in Sweden have discovered an antibody with the potential to protect against Strep A infection, as well as a rare form of antibody binding, that leads to an effective immune response against bacteria. The discovery could explain why so many Group A strep vaccines have failed. The results are published in EMBO Molecular medicine. Group A streptococci have several ways

https://www.medicine.lu.se/article/antibody-discovery-paves-way-new-therapies-against-group-streptococcal-infections - 2025-10-05

Stem cells programmed to produce insulin in people with type 1 diabetes or to repair the heart muscle after a heart attack. Gene and cell therapies that improve cancer treatments. These new and innovative therapies have the potential to cure, alleviate and treat diseases where traditional medicines are currently insufficient. The monk Gregor Mendel set more in motion than he could have imagined wh

https://www.medicine.lu.se/article/advanced-treatments-future-are-soon-here - 2025-10-05

For risk groups, a common cold can be life-threatening. Researchers in Lund have contributed to the development of a new biological medicinal product to treat severe asthma that is worsened by colds. The hope is that the drug will be approved in Sweden next year. Young children, the elderly and patients suffering from chronic lung disease such as asthma and COPD run an increased risk of being affl

https://www.medicine.lu.se/article/when-common-cold-becomes-life-threatening - 2025-10-05

The Lung Bioengineering and Regeneration research group is made up of about 15 researchers focusing on chronic lung disease. The group’s work includes the development of different methods to study disease models for conditions such as COPD and pulmonary fibrosis. One of the researchers, John Stegmayr, has been awarded SEK 700,000 from the Carl Tesdorpf Foundation to expand research into idiopathic

https://www.medicine.lu.se/article/focusing-chronic-lung-disease - 2025-10-05

How much water do we need to drink to stay healthy? How do different diets affect our metabolism? Studies of various hormones in the body are providing diabetes researchers with new answers to these questions. The goal is to develop individualized treatments and dietary recommendations that could lower the risk of developing obesity and diseases such as type 2 diabetes. The endocrine system and th

https://www.medicine.lu.se/article/learning-more-about-endocrine-system-could-lead-fewer-cases-type-2-diabetes-and-obesity - 2025-10-05

Two innovation-driven research projects at Lund University have been awarded a Proof of Concept Grant by the European Research Council, ERC. They relate to biomarkers for predicting who benefits from metformin in the treatment of type 2 diabetes and new technology to enable powerful and focused therapies for the treatment of solid tumours. Charlotte Ling has been awarded an ERC Proof of Concept Gr

https://www.medicine.lu.se/article/erc-grants-research-diabetes-and-immunotherapy - 2025-10-05

For up to 40 years, nearly 800,000 people from Sweden, Norway and Austria have been tracked based on how their BMI and metabolic health – that is, their blood pressure, blood glucose levels and blood fats - affect the risk of suffering from obesity-related cancers. The study shows that those who are metabolically unhealthy are at a higher risk of certain forms of cancer, regardless of their body w

https://www.medicine.lu.se/article/metabolic-health-plays-role-obesity-related-cancers - 2025-10-05

Certain complications during pregnancy bring an increased risk of heart disease later on. However, there is still much to learn about how arteriosclerosis develops between pregnancy and heart disease later in life. A large new study led by researchers from Lund University in Sweden shows that narrowing and calcification of the blood vessels of the heart are more common in women previously affected

https://www.medicine.lu.se/article/complications-pregnancy-linked-increased-risk-heart-disease - 2025-10-05

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene’s activity. The research team’s scientific paper was published in the Journal of Clinical Invest

https://www.medicine.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-10-05

Modern imaging techniques allows researchers to map the structure of the smallest components of cells, such as proteins. By understanding what proteins look like and how they interact with their surroundings, researchers can find keys to more effective drug therapies. In a study led from Lund University, researchers have mapped the structure of a channel in the cell membrane that regulates the tra

https://www.medicine.lu.se/article/mapping-aquaporins-water-channels-cell-membranes - 2025-10-05

During the foetal stage, a number of so-called cell programs run that are vital to the development of the foetus. In a study published in Cell Reports, researchers from Lund University demonstrate that one of these foetal programs appears to protect against acute myeloid leukaemia (AML). “We have used an experimental mouse model that always results in this type of leukaemia. The interesting thing

https://www.medicine.lu.se/article/new-insights-foetal-development-may-protect-against-leukaemia - 2025-10-05

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund University and it is now being tested in patients for the first time. The transplantation product is generated from embryonic stem cells and functions to replace the dopamine nerve cells which are lost in the p

https://www.medicine.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-10-05

Is it possible to know exactly where to point a microscope in order to capture the precise moment a bacterium or a virus infects a cell? In order to take high resolution microscopic images of living biological material, you need to know exactly where to point the microscope. Researchers at Lund University in Sweden have now developed a software solution for smart, data-driven microscopy, which mak

https://www.medicine.lu.se/article/smart-microscopy-works-out-where-take-picture - 2025-10-05

Do you want to learn more about medical humanities? Birgit Rausing Centre for Medical Humanities is Lund University's youngest interdisciplinary knowledge centre. Now the centre has a new website - and a blog.  Website address: www.medical-humanities.lu.se Blog address: med-hum-en.blogg.lu.se Welcome to visit the Birgit Rausing Centre online!

https://www.medicine.lu.se/article/visit-new-website-about-medical-humanities - 2025-10-05

Researchers at Lund University Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major nexus of gene expression regul

https://www.medicine.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-10-05

Three researchers at Lund University in Sweden, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. One of these researchers is neuroscientist Oskar Hansson, who will use blood tests for rapid screening of drugs in the treatment of Alzheimer’s disease. The European Rese

https://www.medicine.lu.se/article/erc-advanced-grant-alzheimers-research - 2025-10-05

Swedish obstetricians and gynecologists are noticeably more emotionally stable and conscientious compared to the majority of the Swedish population. Based on the doctors' personalities, their decision-making styles differ in emergency situations. The research study from Lund University is now published in Scientific Reports. Personality is usually summarized in five traits - the so-called "big fiv

https://www.medicine.lu.se/article/obstetricians-more-emotionally-stable-most - 2025-10-05

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study led from Lund University in Sweden now shows how two molecular mechanisms can work together make the bacterium extra resistant. “Using this

https://www.medicine.lu.se/article/revealed-molecular-superpower-antibiotic-resistant-bacteria - 2025-10-05

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus. The modified antibodies have been tested in human cells and with mice. Many antibodies used to treat covid infection during the pandemic have been so-called neutralizin

https://www.medicine.lu.se/article/cocktail-modified-antibodies-provides-strong-effect-against-sars-cov-2 - 2025-10-05

Almost 14 million viewers have watched Anils Seth’s TED Talk “Your brain hallucinates your conscious reality”. In the beginning of May, he visits Lund University and Neuroscience Day to give this year's prestigious Segerfalk lecture. We meet on zoom for a conversation about AI, the mystery of consciousness and – of course – to find out what he knew about Sweden. … how would you explain consciousne

https://www.medicine.lu.se/article/hello-there-anil-seth - 2025-10-05