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Intensive efforts are being made in medical research to discover the genomic causes of undiagnosed hereditary diseases. Persistent work and new technology are providing answers to several previously unsolved, enigmatic neurological disorders. Spinocerebellar ataxia type 4 was one of these, but now a research team in Lund, Sweden, have identified the gene that is responsible. Almost half a million

https://www.medicine.lu.se/article/researchers-have-found-genetic-cause-type-hereditary-ataxia-sca4-long-unresolved-conundrum - 2025-11-07

Christopher Douse, a new group leader at the Faculty of Medicine at Lund University, has been awarded the Ben Barres Early Career Acceleration Award by The Chan Zuckerberg Initiative. This award includes a $1.2 million grant to support his lab’s exploration of the repetitive portion of the human genome, so-called ‘genomic dark matter’, and its role in human brain development and degeneration. Repe

https://www.medicine.lu.se/article/exploring-genomic-dark-matter-christopher-douse-awarded-12m-grant-chan-zuckerberg-initiative - 2025-11-07

Through a simple, inexpensive five-minute test, one can obtain an initial indication of whether a child has ADHD or not. This is demonstrated by a research team at Lund University, connecting the changes in the cerebellum associated with ADHD to a finger-tapping test. The test can be used as a complement to existing diagnostic methods. ADHD is considered the most common neurodevelopmental disorder

https://www.medicine.lu.se/article/five-minute-test-indicate-adhd - 2025-11-07

The development of a new treatment strategy for bacterial infections and sepsis is being led by researchers at Lund University. In a study the researchers demonstrate how they, by mimicking a substance naturally present in the body, can neutralize toxic substances from bacteria and thereby mitigate harmful inflammation that could otherwise lead to sepsis. “Despite decades of research, there are cu

https://www.medicine.lu.se/article/step-closer-treatment-severe-bacterial-infections-and-sepsis - 2025-11-07

An international team of researchers has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis was led by Lund University, Johns Hopkins University, and the Chinese University of Hong Kong. The study was published in Communications Medicine. Although people with type 2 diabetes are two times mo

https://www.medicine.lu.se/article/new-study-biomarkers-improve-prediction-cardiovascular-disease-type-2-diabetes-2 - 2025-11-07

Aquaporins are proteins that regulate the flow of water in and out of cells. These proteins have been found to play a role in both cancer and type 2 diabetes. Now, a research group at Lund University has succeeded in finding a drug candidate that binds to the protein, something that has been shown to affect the growth capability of leukemia cells. The study is published in PNAS. Aquaporins are wat

https://www.medicine.lu.se/article/blocks-aquaporins-thereby-inhibiting-cancer-growth - 2025-11-07

Much research on diabetes focuses on understanding what happens when the insulin-producing cells are destroyed. Researchers at Lund University have instead chosen to investigate what protects the insulin-producing cells. Their research shows that a protein of the immune system protects the insulin-producing cells from inflammation and death. The study, published in PNAS, is an example of basic res

https://www.medicine.lu.se/article/protein-protects-insulin-producing-cells - 2025-11-07

Do you think that people with obesity have themselves to blame? Tune H Pers tries to dispel persistent myths through his research on the brain's role in the development of obesity. The diabetes researcher at the University of Copenhagen is now awarded the LUDC Leif C. Groop award for his research on obesity and type 2 diabetes. This year's recipient Tune H Pers investigates, among other things, th

https://www.medicine.lu.se/article/tune-h-pers-receives-award-outstanding-research-obesity-and-diabetes - 2025-11-07

Diabetes researchers Allan Vaag and Lena Eliasson are the new coordinators of Lund University Diabetes Centre and the strategic research area Excellence of Diabetes Research in Sweden. Over the next years, they will work to strengthen and further develop ongoing collaborations. Coordinator Allan Vaag and Vice Coordinator Lena Eliasson are new leaders since the beginning of the year and coordinate

https://www.medicine.lu.se/article/new-coordinators-strategic-research-area-diabetes - 2025-11-07

Vasili Hauryliuk, Senior Lecturer in Medical Biochemistry at Lund University, is awarded the Göran Gustafsson Prize in Molecular Biology with the motivation "for pioneering studies of how protein synthesis is regulated in bacteria". The Göran Gustafsson Prize, a total of SEK 33 million, is now awarded to five young researchers from Umeå, Lund, Uppsala, Gothenburg and Stockholm.  The prize is grant

https://www.medicine.lu.se/article/goran-gustafsson-prize-fight-against-antibioticresistance - 2025-11-07

Being able to predict diseases before they develop has become somewhat akin to the search for the Holy Grail. The difference is that research has a greater chance of success in finding what they are looking for than King Arthur's knights did. And in many cases, there are significant health benefits to being able to predict disease risk early: prevention is better than cure. Biomarkers are trace el

https://www.medicine.lu.se/article/new-research-unlocking-secrets-our-blood-early-death-and-diseaserisk - 2025-11-07

How might low-grade inflammation be linked to depression? New research findings show that depression can be alleviated when patients with mild elevations of inflammatory markers in blood samples take omega-3 supplements. The antidepresssant effect was greater in those with low-grade inflammation than in those with no inflammation. “We saw a significant improvement in symptom severity,” says resear

https://www.medicine.lu.se/article/omega-3-can-alleviate-symptoms-depressed-patients-inflammation - 2025-11-07

Applying a peptide coating to sutures, capable of combating both bacteria and inflammation, has been identified as an effective strategy to mitigate wound complications following surgical procedures, as revealed by research led by Lund University. The study has been featured as a cover image in the renowned journal Advanced Healthcare Materials.Globally, more than 300 million surgical procedures a

https://www.medicine.lu.se/article/surgical-sutures-coated-peptide-reduce-infections - 2025-11-07

New research shows that it is possible to induce new bone formation around orthopaedic implants in osteoporotic patients. The study has been published in Acta Biomaterialia. The study, which was led from Lund University in Sweden, is a collaboration with researchers from Lithuania, Germany and China.The Nordic region has the highest incidence of osteoporosis, a disease that makes bone prone to fra

https://www.medicine.lu.se/article/making-bone-alive-ceramic-material-transforming-new-bone-tissue-osteoporotic-patients - 2025-11-07

The guidelines governing the treatment of sudden cardiac arrest exhibit variation across different nations, with treatment strategies often resting on a limited evidential foundation. A randomized international study is underway poised to address some of the most pivotal questions. Encompassing a cohort of 3,500 patients, this study aims to scrutinize the impact of different fever treatments, cont

https://www.medicine.lu.se/article/best-treatment-cardiac-arrest-new-international-study-will-provide-answer - 2025-11-07

A treatment that has reduced plaque development in animals has now been tested in people with psoriasis. Jan Nilsson at Lund University is one of the researchers behind the clinical study that showed a reduced inflammation of the coronary arteries, which in turn may reduce the risk of dying from a heart attack. People with diabetes may also benefit from the treatment in the future. Short facts abo

https://www.medicine.lu.se/article/new-treatment-atherosclerosis-may-reduce-risk-heart-attack - 2025-11-07

Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a first-in-human clinical trial testing a new investigational therapy for Parkinson’s disease aimed at replacing the dopamine cells lost to the disease with healthy ones derived

https://www.medicine.lu.se/article/update-on-stem-pd-clinical-trial-stem-cell-based-transplant-parkinsons-disease - 2025-11-07

By analysing small microvesicles that cells release to communicate with their surroundings in the blood, researchers at Lund University map what happens in the brains of stroke patients. The study published in the scientific journal Stroke expands our understanding of stroke and opens doors to new treatment strategies.
 Ischemic stroke, caused by a blood clot in the brain, is the leading cause of

https://www.medicine.lu.se/article/cell-specific-biomarkers-blood-reflect-what-happens-brain-during-stroke - 2025-11-07

There is a constant war between bacteria and their viruses, bacteriophages, where both try to outsmart each other. An international study led by Lund University provided an important missing bit to the puzzle of how the bacteria defend themselves against phages. This is an important stepping stone towards developing effective phage-based therapies to be used as an alternative to antibiotics. Bacte

https://www.medicine.lu.se/article/war-between-bacteria-and-their-virus - 2025-11-07

The EAT-Lancet diet is a framework designed to promote environmental sustainability while also preventing common diseases such as type 2 diabetes. How do we know if the diet actually works? An international research team studied seven dietary scores and found that two of them were particularly good at evaluating adherence to the diet. Reliable diet scores are important when developing sustainable

https://www.medicine.lu.se/article/research-paves-way-sustainable-dietary-guidelines - 2025-11-07