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Alpha Synuclein Galaxy

Oksana Tymoshchuk, Research Associate | LUNDGAARD LAB The storyThis was an experiment with chronic fibrils, during which we bilaterally injected fibrils into the brains of mice and observed these mice over a period of six months. The image was taken six months after the fibril injection. It was a collaborative project with universities in the United States. Together, we are taking small steps towa

https://www.wcmm.lu.se/alpha-synuclein-galaxy - 2025-08-05

The Elemental Breath: A Chemical Mosaic in Lung Tissue

Bryan Falcones, Postdoc | WESTERGREN THORSSON LAB The storyHidden within the intricate architecture of lung tissue lies a chemical mosaic, a story told by the distribution of elements that govern health and disease. Using the X-ray imaging capabilities at MAX IV laboratory, researchers have illuminated this unseen world with unprecedented detail. At the heart of this process is the synchrotron, a

https://www.wcmm.lu.se/elemental-breath-chemical-mosaic-lung-tissue - 2025-08-05

Cytokine Heatmap

Poojaswini Thimmaraya Reddy, MSc student | CONSIGLIO LAB The storyThe story I want to tell with this art piece is about the complex and varied immune profiles of different women, focusing on the differences in their cytokine levels in serum and follicular fluid. Cytokines are crucial signaling molecules in the immune system that play a key role in inflammation, immune response, and tissue repair.

https://www.wcmm.lu.se/cytokine-heatmap - 2025-08-05

Symmetry

Kelley Swanberg, Postdoc | LUNDGAARD LAB The storyAn intricate web of disparate experimental, signal acquisition, processing and analysis methods within in vivo proton magnetic resonance spectroscopy converges beautifully to depict the cortical metabolic similarities between two distinct species.Research areaThe glymphatic brain clearance system, in vivo functional and metabolic signatures of glym

https://www.wcmm.lu.se/symmetry - 2025-08-05

The Glow of HLS in Celestial Neurons

João Duarte, Associate Professor | DUARTE LAB The storyThis artwork celebrates the wonder and mystery of the microscopic world. A neuron stained for the enzyme hormone-sensitive lipase (HSL) glows like a celestial body in the vast expanse of the cell dish. The bright hues and intricate details highlight the presence of HSL throughout the neuron and in its in dendritic spines, where it interfaces l

https://www.wcmm.lu.se/glow-hls-celestial-neurons - 2025-08-05

Two 50% clinical research positions within the WCMM, LU

Back to news archiveLund University and Skåne University Hospital hereby announce two clinical research positions within the Wallenberg Centre for Molecular Medicine at Lund University (WCMM LU).As part of the first call within the WCMM LU, one combined clinical/research position in each of the fields of: 1) Regeneration and repair in the nervous system and 2) Regeneration and repair in the cardio

https://www.wcmm.lu.se/two-50-clinical-research-positions-within-wcmm-lu - 2025-08-05

Embedded

Oscar van der Have, PhD student | TRAN LUNDMARK LAB The storyWe aim to highlight the vast possibilities that lie hidden in paraffin-embedded biobank tissue samples, through the utilization of new imaging modalities and computer-assisted reconstructions. In this image, we have integrated four types of histological analysis of the same tissue sample – from traditional to cutting-edge – into a single

https://www.wcmm.lu.se/embedded - 2025-08-05

Shortcut

Karin Tran Lundmark, Principal Investigator | TRAN LUNDMARK LAB The storyMost things in this world tends to take the easy way out if possible. This includes the blood in the lung.Research areaPulmonary vascular biology.ImpactThis type of imaging can teach us about the 3D structure of different types of diseases. When combined with other methods it becomes a powerful tool for exploring disease mech

https://www.wcmm.lu.se/shortcut - 2025-08-05

Through Synchrotron Eyes: a Glimpse into Early Heart Development

Niccolò Peruzzi, Postdoc | TRAN LUNDMARK LAB The storyThis piece showcases how synchrotron imaging can reveal the hidden processes that sustain life at its earliest stages. This rendering of a fetal mouse heart portrayed as if crafted from transparent glass, invites viewers to glimpse the delicate yet complex nature of life as it forms. Within this fragile structure lies a vibrant, solid red netwo

https://www.wcmm.lu.se/through-synchrotron-eyes-glimpse-early-heart-development - 2025-08-05

Drawing Immunity Dynamics: Epitrochoid Patterns of Hormone-Modulated Responses

Joan Escrivà Font, PhD student | CONSIGLIO LAB The storyImmune responses vary across individuals. This huge diversity can be measured and summarized to a few estimates that are visualized in aesthetically displeasing plots. One can also use more engaging representations like epitrochoids, which are  typically drawn with Spirographs. Here, we were interested in understanding how feminizing hormone

https://www.wcmm.lu.se/drawing-immunity-dynamics-epitrochoid-patterns-hormone-modulated-responses - 2025-08-05

Titin – the Spiderweb of the Heart & the Mysterious Protein Novex-3

Julia Martinez, PhD student | SMITH LAB The storyMy research focuses on the giant sarcomeric protein Titin, crucial for heart elasticity. While its striated structure is well-known, imaging heart cells revealed its striking clarity. Our current study examines a smaller Titin isoform, Novex-3, which is upregulated in heart failure tissue compared to donor hearts. Novex-3’s location and function in

https://www.wcmm.lu.se/titin-spiderweb-heart-mysterious-protein-novex-3 - 2025-08-05

Blood Vessels: the Tumor´s Silent Climb

Carolina Buizza, PhD student | PAUL-VISSE LAB The storySince beginning my PhD, I’ve carried out countless immunohistochemical experiments. Many weekends have been spent washing and mounting brain sections onto thin glass slides, and countless hours passed in a dark room at the microscope—even on those rare sunny days. Disclaimer: most of these experiments haven’t worked out. Sometimes it’s a fault

https://www.wcmm.lu.se/blood-vessels-tumors-silent-climb - 2025-08-05

Hexokinase II in Human Fibroblast-Like Synoviocyte

Yuan Zhang, Researcher | MAGLIO GROUP The storyProliferative cells depend on altered metabolic pathways to support their active proliferation. Fibroblast-like synoviocytes are the key cells involved in the pathogenesis of rheumatoid arthritis. Those cells show reprogramming of different metabolic pathways, such as glycolysis. Fibroblast-like synoviocytes isolated from rheumatoid arthritis patients

https://www.wcmm.lu.se/hexokinase-ii-human-fibroblast-synoviocyte - 2025-08-05

Life Juxtaposition

Camila Vazquez Echegaray, Postdoc | PEREIRA LAB The storyLife is a constant change, where cells evolve with a raged need for more. And on the way they explore all the boundaries of shapes, colors, flavors and experiences. In the midst of this mess is when cells find meaning and sense, redefining their identity amid the juxtapositions that choices may present. After all, that’s life.Research areaCe

https://www.wcmm.lu.se/life-juxtaposition - 2025-08-05

Aurora Bloom: a Cosmic Burst of Cellular Life

Kabilan Sakthivel, Postdoc | SWAMINATHAN LAB The storyDeep within the tissues of life, an organoid pulses with vibrant energy. Each nucleus, a spark, contributes to a grand mosaic. Together, cells form a living constellation, a galaxy of fractal-like patterns. Once a simple cluster, it blossomed after a surge of energy, guided by an unseen rhythm. Silent communication between cells creates intrica

https://www.wcmm.lu.se/aurora-bloom-cosmic-burst-cellular-life - 2025-08-05

Spring and Fall

Shubhangini Tiwari, postdoc | PAUL-VISSE LAB The storyThis image is inspired from the poem “Spring and Fall” by the English poet Gerard Manley Hopkins, depicting several metaphorical layers - Youth & Aged Mortality or Happiness & SadnessResearch areaNeurological disorders, neurovascular disease mechanisms, Parkinson’s disease.ImpactThis picture talks about the evolution of emotions in a human life

https://www.wcmm.lu.se/spring-and-fall - 2025-08-05

Announcement of tenure track position

Back to news pageOne research positions at the level of Associate Senior Lecturer (Assistant Professor) is now open within the Wallenberg Centre for Molecular Medicine at Lund University (WCMM LU).Welcome with your application – the deadline for submission is March 4, 2019Link to the announcementWCMM LU are recruiting outstanding young scientists with international research experience within the a

https://www.wcmm.lu.se/announcement-tenure-track-position - 2025-08-05

Lost by p129

Robert Carlsson, Senior Scientist | PAUL-VISSE LAB The storyLoss of neuronal function and dopamine activity in Parkinson’s disease coincides with aggregation of phosphorylated alpha-synucein. The alpha-synuclein is phosphorylated at position 129, as visualized on the pipette. Dopamine activity is assessed by the loss of brown staining on brain cross-sections.Research areaNeurological disorders, ne

https://www.wcmm.lu.se/lost-p129 - 2025-08-05

Macrophages: the Vigilant Sentinels of the Nasal Great Wall

Na Liu | LUNDGAARD LAB The storyThis image depicts the immunofluorescent staining of mouse nasal mucosa. The structure of the nasal mucosa resembles a Great Wall and serves a similar function—a strong barrier protecting the body’s defensive gateway. Along this "nasal Great Wall," the red-stained macrophages stand out prominently. These powerful immune cells, embedded within the mucosa, act like vi

https://www.wcmm.lu.se/macrophages-vigilant-sentinels-nasal-great-wall - 2025-08-05