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Soil microbial growth and activity are generally assumed to recover rapidly after dissipation of organic toxicants. We studied the effects of four readily degradable isothiazolinone biocides (benzisothiazolinone, BIT; methylisothiazolinone, MIT; octylisothiazolinone, OIT; 4,5-dichloro-2-octyl-isothiazolinone, DCOIT) on bacterial growth, fungal growth, basal respiration, and substrate-induced respi
Chinese culinary culture has a long history of development and has unique characteristics, attracting people from all over the world. As a world-renowned restaurant award, the Michelin Guide in China plays an influential role in introducing Chinese culinary culture to the world and destination branding, while few studies have investigated Michelin-starred restaurants (MSRs) in China. This study th
This paper investigates the evolution of inequality in China (1978–2015) through the lens of a dynamic spatial general equilibrium model with migration and capital formation. Due to an urban-rural income gap there is domestic migration from the rural to the urban areas which tends to reduce inequality. The resulting increase in urban house prices can, however, constitute an endogenous barrier to f
Magnetic fields play a key role in driving a broad range of dynamic phenomena in the atmospheres of the Sun and other stars. Routine and accurate measurements of the magnetic fields at all the atmospheric layers are of critical importance to understand these magnetic activities, but in the solar and stellar coronae such a measurement is still a challenge due to the weak field strength and the high
Chronic kidney disease of non-traditional origin (CKDnt) and acute kidney injury (AKI) often affect heat-stressed Mesoamerican manual workers. Inflammation occurs concurrently with AKI in this population, but its role remains unknown. To explore links between inflammation and kidney injury in heat stress, we compared levels of inflammation-related proteins in cutters with and without increasing se
Globally, biodiversity offsetting is used to balance negative impacts on biodiversity and ecosystem services caused by exploitation. In Sweden, there is an increasing interest in biodiversity offsetting in urban planning. However, there is limited understanding about the use of the concept in a municipal context. This study aims to examine and critically reflect on the uptake and use of biodiversi
Tissue clearing is commonly used for whole-brain imaging but seldom used for brain slices. Here, we present a simple protocol to slice, immunostain, and clear sections of adult rat brains for subsequent high-resolution confocal imaging. The protocol does not require toxic reagents or specialized equipment. We also provide instructions for culturing of rat brain slices free floating on permeable cu
SPATA2 mediates the recruitment of CYLD to immune receptor complexes by bridging the interaction of CYLD with the linear ubiquitylation assembly complex (LUBAC) component HOIP. Whether SPATA2 exhibits functions independently of CYLD is unclear. Here, we show that, while Cyld−/− and Spata2−/− mice are viable, double mutants exhibit highly penetrant perinatal lethality, indicating independent functi
Induced pluripotent stem cell (iPSC) reprogramming is inefficient and understanding the molecular mechanisms underlying this inefficiency holds the key to successfully control cellular identity. Here, we report 24 reprogramming roadblock genes identified by CRISPR/Cas9-mediated genome-wide knockout (KO) screening. Of these, depletion of the predicted KRAB zinc finger protein (KRAB-ZFP) Zfp266 stro
Introduction: Plasma-measured tau phosphorylated at threonine 217 (p-tau217) is a potential non-invasive biomarker of Alzheimer's disease (AD). We investigated whether plasma p-tau217 predicts subsequent cognition and positron emission tomography (PET) markers of pathology in autosomal dominant AD. Methods: We analyzed baseline levels of plasma p-tau217 and its associations with amyloid PET, tau P
Type 2 diabetes (T2D) is a polygenic disease and studies to understand the etiology of the disease have required selectively bred animal models with polygenic background. In this review, we present two models; the Goto-Kakizaki (GK) rat and the Oikawa-Nagao Diabetes-Prone (ON-DP) and Diabetes-Resistant (ON-DR) mouse. The GK rat was developed by continuous selective breeding for glucose tolerance f
This paper investigates the impact of public policies aimed to foster entrepreneurship on the national entrepreneurial culture of a country. While most of the existing studies focus on the direct impact of policies on entrepreneurship outcomes, we propose that the impact of policies on entrepreneurial culture may be even more important for the development of economies in the long term. Using data
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium. Early and accurate diagnosis is essential, while ongoing efforts to risk stratify pat
Ultra-scaled ferroelectrics are desirable for high-density nonvolatile memories and neuromorphic computing; however, for advanced applications, single domain dynamics and defect behavior need to be understood at scaled geometries. Here, we demonstrate the integration of a ferroelectric gate stack on a heterostructure tunnel field-effect transistor (TFET) with subthermionic operation. On the basis
This article discusses the issue of the right to health care for irregularised migrants in Sweden, from a human rights perspective. An extended right to health care for irregularised migrants came into effect through a legislative amendment in 2013. By exploring the legislative process before the new Act on Health Care to Some Foreigners Who Reside In Sweden Without the Necessary Permits in 2013,
I kapitlet diskuteras tre tolkningar av Arendt, tolkningar som alla har stöd i Arendts text men som vidareutvecklats på olika sätt av samhällsvetare och filosofer. I den första tolkningen är det bristen på tillgodoseende av mänskliga rättigheter för papperslösa om står i fokus. En viktig anledning till denna brist ligger i kopplingen mellan invandringsreglering och mänskliga rättigheter, att state
This article analyses sanctuary initiatives intended to change the situation of ‘irregularised residents’. Through fieldwork, three main activities are identified: assistance for welfare services, alternatives to inaccessible services, and inventing new ways of organising togetherness in the city. The role of activists in the initiatives links to discussions within Critical Human Rights literature
The article analyses the social constructions of rights as they come about through Swedish delegations preparing refugees for resettlement in Sweden, under the Cultural Orientation Programme (COP). COPs are analysed as an activity that manifests a need to convey rights. Fieldwork was conducted through video observations of COPs in Kenya and Sudan. Our empirical findings show how the Swedish offici
Asylkommissionen har bildats av forskare och personer med omfattande kunskap om migration och asylsökandes liv och villkor i Sverige, med syfte att initiera en granskning som utgår från asylsökandes levda erfarenheter och perspektiv. Bakgrunden till kommissionen är de återkommande rapporterna om en svår situation bland barn, unga och vuxna asylsökande, såsom oförutsägbara och inhumana beslut, ökanThe Asylum Commission has been formed by researchers and people with extensive knowledge of migration and asylum seekers’ living conditions in Sweden, with the aim of initiating enquiries based on asylum seekers’ lived experiences and perspec-tives.The background to the Commission is recurring reports of a difficult situation among children, adolescents and adult asylum seekers, such as unpredicta
