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Autonomic dysfunction is a prevalent feature of Parkinson's disease (PD), mediated by disease involvement of the autonomic nervous system. Chronotropic incompetence (CI) refers to inadequate increase of heart rate in response to elevated metabolic demand, partly dependent on postganglionic sympathetic tone. In a retrospective study, PD patients with/without CI were identified. We show that PD with
This work concerns reduction of the peak flow rate of a district heating grid,a key system property which is bounded by pipe dimensions and pumpingcapacity. The peak flow rate constrains the number of additional consumersthat can be connected, and may be a limiting factor in reducing supplytemperatures when transitioning to the 4th generation of district heating.We evaluate a full year of operatio
AI technologies have led to new ways of thinking about data, knowledge, and organizations. Despite the arguments that data speak for themselves, the era of datafication demands revisiting data and knowledge and reflecting on new ways of theorizing. Considering that working with data is important for most employees, there is a need to investigate how the knowing of data can be achieved. In this pap
In this paper, we review the development of critical management studies, point at problems and explore possible developments. We begin by tracing out two previous waves of critical management studies. We then focus on more recent work in critical management studies and identify ten over-arching themes (Academia, alternatives organizations, control and resistance, discourse, Foucauldian studies, ge
Modern societies rely on critical flows of essential goods and services to ensure societal safety. The covid-19 pandemic highlighted the importance of upholding critical flows during a crisis. This comprehensive study provides novel insights into interdependencies and resilience of critical flows by carrying out a longitudinal and holistic study throughout the pandemic in Sweden of four sectors: t
Across cultures and languages spontaneous speech is often accompanied bygestures. It is a popular belief that people in Italy gesture more than peoplein Northern Europe, such as in Sweden. Despite this general assumption fewstudies empirically investigate cultural differences in gesture frequency andgesture function under similar circumstances. This study compares the spokenand gestural behaviours
Many insects utilise the polarisation pattern of the sky to adjust their travelling directions. The extraction of directional information from this sky-wide cue is mediated by specialised photoreceptors located in the dorsal rim area (DRA). While this part of the eye is known to be sensitive to the ultraviolet, blue or green component of skylight, the latter has only been observed in insects activ
Ataxia telangiectasia (A-T), caused by biallelic variants in the ATM gene, is a multisystemic and severe syndrome characterized by progressive ataxia, telangiectasia, hyperkinesia, immunodeficiency, increased risk of malignancy, and typically death before the age of 30. In this retrospective study we describe the phenotype of 14 pediatric and adult A-T patients evaluated at the Karolinska Universi
As the dimensions of interconnects in integrated circuits continue to shrink, an urgent need arises to understand the physical mechanism associated with electromigration. Using x-ray nanodiffraction, we analyzed the stresses in Blech-structured pure Cu lines subjected to different electromigration conditions. The results suggest that the measured residual stresses in the early stages of electromig
Syftet med den här texten är att beskriva olika former av mikroaggressioner och ge exempel på hur de kan ta sig uttryck. Vi kommer att gå igenom hur de hanteras av de som utsätts, samt diskutera varför yrkesverksamma som träffar människor i sitt arbete behöver ha kunskap om mikroaggressioner. I den här texten kommer vi framför allt att belysa situationen för hbtq-personer, alltså personer som är hSyftet med den här texten är att beskriva olika former av mikroaggressioner och ge exempel på hur de kan ta sig uttryck. Vi kommer att gå igenom hur de hanteras av de som utsätts, samt diskutera varför yrkesverksamma som träffar människor i sitt arbete behöver ha kunskap om mikroaggressioner. I den här texten kommer vi framför allt att belysa situationen för hbtq-personer, alltså personer som är h
This study investigates the suitability of heat conduction calorimeters for determining the specific heat capacity of solid and liquid substances. Accurate and precise measurements were obtained for various substances, including water, ethylene glycol, the ionic liquid [EMIM][TCM], and copper, with relative standard deviations averaging less than 1%. Measurements on [EMIM][DCA] indicated a systema
Airborne mineral dust is sensitive to climatic changes, but its response to orbital forcing is still not fully understood. Here, we present a reconstruction of dust input to the Subarctic Pacific Ocean covering the past 190 kyr. The dust composition record is indicative of source moisture conditions, which were dominated by precessional variations. In contrast, the dust flux record is dominated by
The fast evolution of the QGP makes its interaction with jets an inherently time-dependent process. However, this crucial dimension is missing from traditional jet quenching measurements, which hence provide a mere average quantification of the medium properties. Jet substructure observables provide an effective strategy to access the QGP time structure. By identifying the recursive steps of a nov
Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three in
We extend the ecological component (ECOGEM) of the carbon-centric Grid-Enabled Integrated Earth system model (cGEnIE) to include a diatom functional group. ECOGEM represents plankton community dynamics via a spectrum of ecophysiological traits originally based on size and plankton food web (phyto- and zooplankton; EcoGEnIE 1.0), which we developed here to account for a diatom functional group (Eco
