Search results

Filter

Filetype

Your search for "*" yielded 547120 hits

Drug-coated balloons versus drug-eluting stents for small non-complex de novo coronary artery lesions : A segment-level propensity score matched analysis from SCAAR

BACKGROUND: The REC-CAGEFREE trial showed that drug-coated balloons (DCB) did not achieve non-inferiority in the treatment of non-complex de novo lesion compared to a strategy of drug-eluting stents (DES). However, a prespecified subgroup analysis of arteries sized <3.0 mm revealed no difference in the device-oriented outcome compared to DES. The aim of present study was to validate that finding i

Palaeoenvironmental changes recorded at the Velika Vrbica loess-palaeosol sequence, Wallachian Basin, during MIS 3–MIS 1

This study presents a detailed investigation of the Velika Vrbica loess-palaeosol sequence, situated in the Wallachian Basin of northeastern Serbia, with the aim to reconstruct palaeoenvironmental changes spanning Marine Isotope Stages (MIS) 3 to 1. Using optically stimulated luminescence (OSL) dating, low field magnetic susceptibility (χlf), and mass accumulation rates (MARs), we have developed a

Biological Soil & Water Conservation. The Vetiver Grass as an example.

This book summarises fundamental methodologies in biological soil and water conservation measures, using the versatile Vetiver grass as a prime example. The material is derived from various student compendia and extension information letters on soil science and soil and water conservation written by Associate Professor Emeritus H. Jonas Åkerman between 1980 and 2000. Over a decade of long-term ass

Infrastructuring the policymaking, funding and positioning of libraries : unpacking tensions in public library policies in three European cities

Public libraries are increasingly acknowledged as important social infrastructures that can stimulate a sense of community, social cohesion and mental wellbeing. This paper investigates how (inter)national, provincial and local policies conceptualise and fund libraries as social infrastructures in three European cities. Drawing on 32 semi-structured interviews with library management and associatiPublic libraries are increasingly acknowledged as important social infrastructures that can stimulate a sense of community, social cohesion and mental wellbeing. This paper investigates how (inter)national, provincial and local policies conceptualise and fund libraries as social infrastructures in three European cities. Drawing on 32 semi-structured interviews with library management and associati

PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation

Pseudouridine synthases (PUSs) catalyze the isomerization of uridine (U)-to-pseudouridine (Ψ) and have emerging roles in development and disease. How PUSs adapt gene expression under stress remains mostly unexplored. We identify an unconventional role for the Ψ "writer" PUS10 impacting intracellular innate immunity. Using Pus10 knockout mice, we uncover cell-intrinsic upregulation of interferon (I

Japan’s UN funding cut leaves women’s rights in the lurch

Japan's January withdrawal of funding from the UN Committee on the Elimination of Discrimination against Women highlights its aversion to addressing gender equality issues at home. Despite externally presenting a commitment to progressive gender norms, a tension between Japan's international image and its domestic reality persists. Japan continues to rank low in major gender equality indexes as re

Global Queer Agonism : Normative Theory of the European Union in Times of Dissensus Over LGBT Equality

In times of heightened dissensus over the liberal democratic order, normative theories of the EU need to adapt to be able to capture how the promotion and enforcement of values go hand in hand with their contestation. Research on global LGBT politics has shown that the promotion and enforcement of LGBT equality make possible and shape the anti-LGBT dissent it seeks to combat. Understood as a parad

Practice lab project: a report from an autoethnographic assignment with students in higher music education

This presentation focuses on a project at an early stage of development. The aim of the practice lab project is twofold: (i) to strengthen the competence among students in higher music education with regards to the topic of practice, and (ii) contribute to research on musical practice and skill acquisition. The project is conducted at Malmö Academy of Music (Lund university). Students take part in

Sensorimotor relationship and musical affordances

Recent years has seen a number of music researchers taking interest in the concept of affordances. Although interpretation of the concept varies, a common denominator is that affordances are opportunities for actions emerging between a subject and the environment. As such, it is an analytical perspective that highlights material and embodied dynamics of musical practice, dimensions central to musi

Concordance between the updated Elecsys cerebrospinal fluid immunoassays and amyloid positron emission tomography for Alzheimer's disease assessment : findings from the Apollo study

OBJECTIVES: The Apollo study was designed to support the clinical performance verification of the adjusted cutoffs of the Elecsys® β-Amyloid(1-42) (Aβ42) cerebrospinal fluid (CSF) II, β-Amyloid(1-40) (Aβ40) CSF, Phospho-Tau (181P) (pTau) CSF and Total-Tau (tTau) CSF immunoassays (Roche Diagnostics International Ltd) for measuring fresh CSF samples, and assess the concordance of the Elecsys CSF pTa

Swedish så and the narrative domain

The Swedish particle så is attested in different usages. In one of these, så introducesassertive clauses forming the foreground, or the skeleton, of a narrative. It is argued that, ifthe distribution of this particular particle is to be captured in a theory of syntax, such atheory needs to incorporate notions relating to narrative discourse or, in other words, atheory in which grammatical statemen

Priority Health Conditions and Global Life Expectancy Disparities

IMPORTANCE: Life expectancy is a composite health measure reflecting acute and life-course exposures. Identifying conditions behind disparities in life expectancy can guide policy, planning, and financing to battle the most urgent health problems.OBJECTIVE: To examine the contribution of 33 causes of death to life expectancy disparities, highlighting 2 sets of priority conditions-8 infectious and

In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody–Associated Vasculitides Identifies Distinct Clinical Phenotypes

Objective: The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides are heterogeneous disorders. The aim of this study was to identify and characterize subgroups of patients based on sex, ANCA, age at diagnosis, and organ involvement. Methods: In total, 1,167 patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) were retrospectively recruited to the s

The probability of cerebral amyloid angiopathy according to the Simplified Edinburgh CT criteria in a large, unselected lobar intracerebral hemorrhage population

PURPOSE: Early identification of the underlying cause of intracerebral hemorrhage (ICH) is important for treatment and prognosis. This study aims to investigate the association of hematoma volume and other clinical parameters on the distribution of cerebral amyloid angiopathy (CAA) probability according to the simplified Edinburgh CT criteria in a large, unselected intracerebral hemorrhage (ICH) p

Maxwell's demon across the quantum-to-classical transition

In scenarios coined Maxwell's demon, information on microscopic degrees of freedom is used to seemingly violate the second law of thermodynamics. This has been studied in the classical as well as the quantum domain. In this paper, we study an implementation of Maxwell's demon that can operate in both domains. In particular, we investigate information-to-work conversion over the quantum-to-classica

Influence of Comorbidity on Endovascular Thrombectomy Outcomes for Medium‐Vessel Occlusion Stroke: A Nationwide Prospective Observational Study

BackgroundComorbidity burden may affect the outcome following endovascular thrombectomy (EVT) for medium‐vessel occlusions. Since patients with high comorbidity burden are likely to be underrepresented in trials on EVT for medium‐vessel occlusions, observational data are needed to assess the benefit of EVT for these patients.MethodsWe conducted an observational study on all prestroke independent p

The potential for minimally invasive intracerebral hemorrhage evacuation in routine healthcare : applicability of the ENRICH trial criteria to an unselected cohort

Objective: Following the favorable outcomes demonstrated by the Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ENRICH) trial in supratentorial intracerebral hemorrhage (ICH) patients treated with minimally invasive surgery (MIS), and considering the increasing interest in MIS, we aimed to assess the potential eligibility rate for ICH patients in Sweden. Methods: All patients with sp

Governing Street-Level Bureaucracies : The Organizational Shaping of Caseworkers

This book examines how caseworkers are governed in today’s street-level bureaucracies. It redefines our understanding of public sector governance by highlighting the subtle, informal, and everyday forms of organizational governance that shape caseworkers’ subjectivities beyond formal policies and professional identities. Based on four distinct types of normative governance – ‘governance by discour