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Ultrastable, high-repetition-rate attosecond beamline for time-resolved XUV-IR coincidence spectroscopy

The implementation of attosecond photoelectron-photoion coincidence spectroscopy for the investigation of atomic and molecular dynamics calls for a high-repetition-rate driving source combined with experimental setups characterized by excellent stability for data acquisition over time intervals ranging from a few hours up to a few days. This requirement is crucial for the investigation of processe

In pursuit of a more socially relevant audit in the context of international standardisation

This chapter aims to enhance our understanding of the implications international standardisation have for audit innovation at the national level. The study analyses the ways in which transnational regulation effectuates institutional constraints on audit innovation in Sweden as a setting to discuss the capacity for the audit profession to innovate and make audits more socially relevant. Based on d

Complement-mediated kidney diseases: Genotype, phenotype and inhibition studies

Complement-mediated kidney diseases are ultrarare conditions characterized by excess complement activation related in most cases to complement gene variants or circulating autoantibodies. These conditions are chronic and can lead to kidney failure. They include atypical hemolytic uremic syndrome (aHUS), C3 glomeru-lopathy (C3G), and, to a certain extent, immune complex-membranoproliferative glomer

Utvecklingen av etiska koder för revisorer

I det här kapitlet beskrivs och diskuteras hur utvecklingen av etiska reglerför revisorer har skett i samverkan med utvecklingen av branschen ochsamhället. Det framgår hur regler använts för att disciplinera revisorernaoch för att öka intressenternas förtroende när det behövts för att stärkaden professionella legitimiteten och yrkets status i samhället.

Evaluation of Processed Nerve Allograft in Peripheral Nerve Surgery : A Systematic Review and Critical Appraisal

Background: Peripheral nerve injuries cause substantial problems when not treated properly. A specific problem is reconstruction of nerve defects, which can be treated in different ways. This study aimed to systematically review whether processed nerve allograft (PNA) is justified in reconstruction of a nerve defect in patients after posttraumatic or iatrogenic peripheral nerve injury and to compa

Pulcaffeate, a Trimeric Caffeic Acid Derivative from Bourreria pulchra

The trimeric caffeic acid derivative pulcaffeate (1) was isolated from the organic crude extract of the roots of Bourreria pulchra (Boraginaceae). The biosynthesis of 1 appears to involve an intramolecular Diels-Alder reaction between a cyclohexa-1,3-diene intermediate, generated by the oxidation of the aromatic ring of a cinnamic acid unit, and the conjugated double bond of a caffeic acid unit. T

The evolutionary maintenance of ancient recombining sex chromosomes in the ostrich

Sex chromosomes have evolved repeatedly across the tree of life and often exhibit extreme size dimorphism due to genetic degeneration of the sex-limited chromosome (e.g. the W chromosome of some birds and Y chromosome of mammals). However, in some lineages, ancient sex-limited chromosomes have escaped degeneration. Here, we study the evolutionary maintenance of sex chromosomes in the ostrich (Stru

Activity recovery for differently shaped objects in quantitative SPECT

Objective. The aim was to theoretically and experimentally investigate recovery in SPECT images with objects of different shapes. Furthermore, the accuracy of volume estimation by thresholding was studied for those shapes. Approach. Nine spheres, nine oblate spheroids, and nine prolate spheroids phantom inserts were used, of which the six smaller spheres were part of the NEMA IEC body phantom and

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Artikel på danska om skandalen när kung Valdemar av Sverige blev förälskad i sin svägerska Jutta av Danmark.Historien om en svensk konge og en dansk prinsesse, hvis forelskelse i hinanden var med til at udløse borgerkrigen, der rev Sverige i stykker

Diverse Lava Flow Morphologies in the Stratigraphy of the Jezero Crater Floor

We present a combined geomorphologic, multispectral, and geochemical analysis of crater floor rocks in Jezero crater based on data obtained by the Mast Camera Zoom and SuperCam instruments onboard the NASA Mars 2020 Perseverance rover. The combined data from this analysis together with the results of a comparative study with geologic sites on Earth allows us to interpret the origins of rocks expos

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Översättning och bearbetning till nederländska av min biografi om drottning Kristina.

An mTRAN-mRNA interaction mediates mitochondrial translation initiation in plants

Plant mitochondria represent the largest group of respiring organelles on the planet. Plant mitochondrial messenger RNAs (mRNAs) lack Shine-Dalgarno-like ribosome-binding sites, so it is unknown how plant mitoribosomes recognize mRNA. We show that “mitochondrial translation factors” mTRAN1 and mTRAN2 are land plant–specific proteins, required for normal mitochondrial respiration chain biogenesis.

Evidence of Unrecognized Indoor Exposure to Toxic Chlorophenols and Odorous Chloroanisoles in Denmark, Finland, and Norway

Production and use of chlorophenols (CPs) are being phased out around the globe, but with considerable lag in some highly populated countries. The process could be incentivized by leading countries sharing their experiences on problems that occurred, including the built environment. We previously reported that Swedish industry and authorities promoted CPs, including pentachlorophenol (PCP), as wooProduction and use of chlorophenols (CPs) are being phased out around the globe, but with considerable lag in some highlypopulated countries. The process could be incentivized by leading countries sharing their experiences on problems thatoccurred, including the built environment. We previously reported that Swedish industry and authorities promoted CPs,including pentachlorophenol (PCP), as wood p

Comparison of Group-Level and Individualized Brain Regions for Measuring Change in Longitudinal Tau Positron Emission Tomography in Alzheimer Disease

Importance: Longitudinal tau positron emission tomography (PET) is a relevant outcome in clinical trials evaluating disease-modifying therapies in Alzheimer disease (AD). A key unanswered question is whether the use of participant-specific (individualized) regions of interest (ROIs) is superior to conventional approaches where the same ROI (group-level) is used for each participant. Objective: To

BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer

PURPOSE: Invasive lobular carcinoma (ILC) is a subtype of breast cancer accounting for 10% of breast tumors. The majority of patients are treated with endocrine therapy; however, endocrine resistance is common in estrogen receptor-positive breast cancer and new therapeutic strategies are needed. Bromodomain and extraterminal inhibitors (BETi) are effective in diverse types of breast cancer but the

PSI-PSYCHO SCHIZOPHRENIA IMAGING- Hjärnavbildning vid Schizofreni. : Del 4: Ämnesomsättning och Schizofreni

4-5.1 Sammanfattning av Glutamat och GABA vid Schizofreni1H-MRS och kronisk schizofreni1H-MRS visar att alla Schizofreni patienter hade ett signifikant lägre N-AcetylAsparagin-syra(NAA) till Kreatin(Cr) nivåförhållande i frontalloben än kontrollerna. Resultaten indikerar att det finns ett samband mellan det Glutamat-erga systemet och patofysiologin vid Schizofreni. (Szulc et al., 2013).GABA och gl

Role of Orthostatic Hypotension in the Development of Dementia in People with and Without Cardiovascular Disease

Background: Orthostatic hypotension (OH) has been associated with elevated risk of cardiovascular diseases (CVDs) and dementia risk. To better understand the OH-dementia association, we assessed the associations of OH with CVD and subsequent dementia in older adults and considered the temporality of CVD and dementia onset. Methods: This 15-year population-based cohort study included, at baseline,