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Proportionality and the Human Rights of Companies under the echr—Whose Interests Are at Stake?
Quantum gravity phenomenology at the dawn of the multi-messenger era—A review
An online atlas of human plasma metabolite signatures of gut microbiome composition
Human gut microbiota produce a variety of molecules, some of which enter the bloodstream and impact health. Conversely, dietary or pharmacological compounds may affect the microbiota before entering the circulation. Characterization of these interactions is an important step towards understanding the effects of the gut microbiota on health. In this cross-sectional study, we used deep metagenomic s
What Norms Are Social Robots Reflecting? A Socio-Legal Exploration on HRI Developers
By relying on theory from sociology of law and data feminism, this study showcases the norms guiding development in human-robot interaction. This qualitative study consists of an ethnography of the HRI conference 2021 and expert interviews which were merged and analysed using an ethnographic content analysis method on NVivo. The socio-legal data feminist lens enables to pinpoint the lack of clear
Introducing new work on indeterminacy and underdetermination
This paper summarises the contributions to our Topical Collection on indeterminacy and underdetermination. The collection includes papers in ethics, metaethics, logic, metaphysics, epistemology, philosophy of science, philosophy of language and philosophy of computation.
Timely integration of palliative care into cancer care
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Creola bodies and pathogenesis of childhood asthma
Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants
PURPOSETo provide precise age-specific risk estimates of cancers other than female breast and ovarian cancers associated with pathogenic variants (PVs) in BRCA1 and BRCA2 for effective cancer risk management.METHODSWe used data from 3,184 BRCA1 and 2,157 BRCA2 families in the Consortium of Investigators of Modifiers of BRCA1/2 to estimate age-specific relative (RR) and absolute risks for 22 first
Computational Evidence Based Perspective on the Plausible Repositioning of Fluoroquinolones for COVID-19 Treatment
The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a serious global healthcare crisis, so there is an emergence of identifying efficacious therapeutic options. In a setting where there is an unavailability of definitive medication along with the constant eruption of vaccine-related controversies, the drug-repositioning appr
φ meson production in p+Al, p+Au, d+Au, and He 3 +Au collisions at sNN =200 GeV
Small nuclear collisions are mainly sensitive to cold-nuclear-matter effects; however, the collective behavior observed in these collisions shows a hint of hot-nuclear-matter effects. The identified-particle spectra, especially the ϕ mesons which contain strange and antistrange quarks and have a relatively small hadronic-interaction cross section, are a good tool to study these effects. The PHENIX
Editorial
Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus : data from the COVID-19 Global Rheumatology Alliance
Aim To determine characteristics associated with more severe outcomes in a global registry of people with systemic lupus erythematosus (SLE) and COVID-19.Methods People with SLE and COVID-19 reported in the COVID-19 Global Rheumatology Alliance registry from March 2020 to June 2021 were included. The ordinal outcome was defined as: (1) not hospitalised, (2) hospitalised with no oxygenation, (3) ho
Poly(arylene alkylene)s functionalized with perfluorosulfonic acid groups as proton exchange membranes for vanadium redox flow batteries
With the aim to develop vanadium redox flow battery (VRFB) membranes beyond state of the art, we have in the present work functionalized poly(p-terphenylene)s with highly acidic perfluorosulfonic groups and investigated their performance as proton exchange membranes (PEMs). Consequently, two poly(p-terphenylene alkylene)s tethered with perfluoroalkylsulfonic acid and perfluorophenylsulfonic acid,
Treatment practices and outcomes in incident peritoneal dialysis patients : The Swedish Renal Registry 2006-2015
Background: Therapeutic developments have contributed to markedly improved clinical outcomes in peritoneal dialysis (PD) during the 1990s and 2000s. We investigated whether recent advances in PD treatment are implemented in routine Swedish care and whether their implementation parallels improved patient outcomes. Methods: We conducted an observational study of 3122 patients initiating PD in Sweden
Ecotoxicity of isosorbide acrylate and methacrylate monomers and corresponding polymers
Isosorbide is a well-investigated and accessible biomass-derived compound that has found wide use in medicine, cosmetics, and material sciences. The efforts to employ this rigid bicyclic diol as a sustainable building block in high-performance biobased plastics for, e.g., the engineering, coating, and packaging sectors have grown sharply in recent years. Due to the biomass origin, there is an impl
Mepolizumab for Eosinophilic Granulomatosis With Polyangiitis: A European Multicenter Observational Study
ObjectiveMepolizumab proved to be an efficacious treatment for eosinophilic granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the randomized, controlled MIRRA trial. In a few recently reported studies, successful real-life experiences with the approved dose for treating severe eosinophilic asthma (100 mg every 4 weeks) were observed. We undertook this study to assess the
Polarization of Λ and ¯Λ Hyperons along the Beam Direction in Pb-Pb Collisions at √sNN=5.02 TeV
Grafts Outside the United States
The market of aortic endografts is in continuous development. Several endografts that have gained the CE mark are under investigation by the FDA before launching in the US market. This chapter describes their peculiarities and the evidence acquired with the use of these endografts. Since the majority of the devices described in this chapter have been recently introduced, the evidence on the feasib