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Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the accumulation of β-amyloid (Aβ) peptides and phosphorylated tau (P-tau) proteins in the brain, leading to cognitive decline and memory impairment. Despite extensive research, the exact mechanisms of AD pathogenesis remain elusive, and reliable biomarkers for early diagnosis and disease monitoring are still ne
Hazel (Corylus avellana) has been abundant in the vegetation of northern and central Europe since the early Holocene and has provided food and materials for humans ever since. Here we use stable carbon isotope (δ13C) values of hazelnut shells to infer woodland openness based on the premise of the “canopy effect”. It is well established that plants growing in dense, shaded forests have lower carbonHazel (Corylus avellana) has been abundant in the vegetation of northern and central Europe since the early Holocene and has provided food and materials for humans ever since. Here we use stable carbon isotope (δ13C) values of hazelnut shells to infer woodland openness based on the premise of the “canopy effect”. It is well established that plants growing in dense, shaded forests have lower carbon
This paper reports cross-section measurements of ZZ production in pp collisions at s=13.6TeV at the Large Hadron Collider. The data were collected by the ATLAS detector in 2022, and correspond to an integrated luminosity of 29 fb−1. Events in the ZZ→4ℓ (ℓ=e, μ) final states are selected and used to measure the inclusive and differential cross-sections in a fiducial region defined close to the anal
A search for high-mass resonances decaying into a Formula Presented-lepton and a neutrino using proton-proton collisions at a center-of-mass energy of Formula Presented is presented. The full run 2 data sample corresponding to an integrated luminosity of Formula Presented recorded by the ATLAS experiment in the years 2015-2018 is analyzed. The Formula Presented-lepton is reconstructed in its hadro
Introduction: Prolonged progress can occur in the first and second stages of labour and may contribute to a negative birth experience. However, previous studies have mainly focused on quantitative aspects or overall birth experience, and little is known about women's experiences of a prolonged passive second stage. Objective: To describe the lived experiences of a prolonged passive second stage of
While organisms have evolved to cope with predictable changes in the environment, the rapid rate of current global change presents numerous novel and unpredictable stressors to which organisms have had less time to adapt. To persist in the urban environment, organisms must modify their physiology, morphology and behaviour accordingly. Metabolomics offers great potential for characterising organism
Background: Inflammatory bowel disease (IBD) is characterized by recurrent inflammation of the gastrointestinal tract and has been linked to an imbalance in gut bacteria. Synbiotics, which combine probiotics and prebiotics, are emerging as potential IBD treatments. Aim: To examine the effects of four synbiotic formulations on intestinal inflammation and peripheral biomarkers in a rodent IBD model
En grön skolgård med många olika träd, buskar och blommor ger stora pedagogiska möjligheter, stärker den biologiska mångfalden, motverkar klimatförändringar och bidrar till barns hälsa och utveckling. Ändå är det idag få kommuner i landet som aktivt satsar på att utveckla skolgårdar med dessa kvaliteter. Finansiering av gröna skolgårdsprojekt behöver öka som en grund för en hållbar framtid!
The judgment by the Grand Chamber of the Court of in Case C-621/21 Intervyuirasht organ na DAB pri MS case has already attracted significant attention for the finding of the Court that women victims of domesticviolence can be considered as members of particular social group for the purposes of recognition of refugee status. This case note presents the the facts of the case and analyses reasoning o
Numerous reports and research studies emphasize the significance of entrepreneurship, especially as a solution to challenges outlined in the UN 2030 Agenda. Interest in entrepreneurship education has significantly increased in recent decades. Experiential learning and the context in which learning occurs are crucial pedagogically, yet their diversity and complexity receive limited attention in the
Background/aims It is unclear whether a reduction in tear secretion contributes to the discomfort experienced by those with prosthetic eyes. Tear secretion has hitherto only been measured with the Schirmer test which may be affected by the pooling of tears behind the prosthesis. In this study, direct imaging of the lacrimal gland has been performed to measure tear secretion in anophthalmic sockets
Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life. Evidence for different treatments of POTS and PCC is limited, and this study aimed to evaluate the feasibility of individually tailored physical e
Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presen
Objective: This paper investigates the critical role of material thickness in freeze-dried pellets for enhancing the storage stability of encapsulated bacteria. Freeze dried material of varying thicknesses obtained from different annealing durations is quantified using Scanning Electron Microscopy (SEM) and X-ray microtomography (μCT), the material thickness is then correlated to the storage stabi
