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Survival following combination chemotherapy in advanced high grade non‐Hodgkin's lymphomas : Relation to proliferative activity of the lymphoma cells

In 18 untreated adult patients (median age 62.5 yr) with advanced non‐Hodgkin's lymphoma of unfavourable histology, thymidine labelling indices (LIs) of the lymphoma cells were assessed. The patients were treated with combination chemotherapy and have been followed for 29–60 (median 52) months or until death. The survival curve had a steep fall during the first 2 yr. Between 2–5 yr after treatment

RELATIONSHIP BETWEEN CYTOGENETIC FINDINGS AND HISTOPATHOLOGY IN NON‐HODGKIN LYMPHOMA

The cytogenetic findings in 70 patients with non‐Hodgkin lymphoma have been correlated with tumor histopathology according to the Kiel classification. Certain chromosome aberrations displayed a nonrandom association with the grade of malignancy: 4 lymphomas out of 6 with 1p+, 5 out of 7 with del(6)(q15), 7 out of 11 with 14q+, and 5 out of 8 with +18 belonged to the high grade malignancy group, wh

Mitotic activity in non-Hodgkinʹs lymphoma. Relation to the kiel classification and to prognosis

At histopathological diagnosis of non-Hodgkin's lymphoma (NHL) the mean number of mitoses in 10 high power fields (×40) was determined in thin sections (2μm) and designated 'mitotic index' (MI). In 38 patients the thymidine labelling index (LI) of the lymphoma cells was also determined. There was a close correlation between MIs and LIs (r=0.81, P<0.001) indicating that MI reflects the proliferativ

Prognostic implication of cytogenetic findings in 106 patients with non-Hodgkin lymphoma

The cytogenetic findings in samples from 106 patients with non-Hodgkin lymphomas (NHL), histopathologically classified according to the Kiel classification, have been correlated with survival time. Clonal chromosomal abnormalities were found in 60 patients, and only normal karyotypes in ten. The chromosome analysis of the remaining samples failed. The failures did not differ in survival compared w

Normal frequency of structural chromosome aberrations in fibroblasts from patients with non‐Hodgkin's lymphoma

The incidence of chromosome aberrations, i.e., chromatid and chromosome gaps, breaks, and exchanges, was studied in cultured skin fibroblasts from 25 untreated patients with non‐Hodgkin's lymphoma (NHL) and 26 controls. The mean frequencies of aberrant cells, and gap, break, and gap+break events per 100 metaphases were 4.2, 1.9, 2.8, and 4.7 in the NHL group, and 5.1, 2.6, 3.2, and 5.8 in the cont

Early oral contraceptive use as a prognostic factor in breast cancer

The survival of 193 premenopausal breast cancer patients was investigated in relation to their history of early use of oral contraceptives. The women were born in 1939 or later and diagnosed in the southern health care region of Sweden. Women, who had started their oral contraceptive use (OC-use) before 20 years of age had a significantly lower survival rate as compared with those who had never us

Optimization of soft X-ray phase-contrast tomography using a laser wakefield accelerator

X-ray phase-contrast imaging allows for non-invasive analysis in low-absorbing materials, such as soft tissue. Its application in medical or materials science has yet to be realized on a wider scale due to the requirements on the X-ray source, demanding high flux and small source size. Laser wakefield accelerators generate betatron X-rays fulfilling these criteria and can be suitable sources for p

Reflections on research collaborations: A call for Nordic research on music education, sustainability, and democracy

Following the EU declaration from 2016 on schools as the most crucial places for societal change needed in order to strengthen democracy, this chapter discusses Nordic music education and music education research within the context of shared challenges in times of rapid demographic changes. Resting on emerging results from the authors’ research projects, the first theme to be discussed is music ed

Mixed abilities within Sweden’s Art and Music Schools: Discourses of inclusion, policy and practice

The focus of this paper is on how Art and Music School leaders talk about the inclusion of children and adolescents with mixed abilities in relation to policy. A starting point is that both an investigation and earlier studies have revealed inclusion problems within Art and Music Schools.The aim of this paper is to investigate the discourses that emerge when Sweden’s Art and Music School leaders t

A “noble battle against darkness, sin, and depravity” : The role of translation in nineteenth-century transnational transfer of philanthropic ideas

Nineteenth-century British philanthropic ideas were implemented in Sweden through the agency of translation. The present investigation of translation as a form of nineteenth-century social-reform activism takes the form of a case study of the Swedish translation of two texts by British social purity campaigner Ellice Hopkins (1836–1904). The purpose of the investigation is to explore how particulaNineteenth-century British philanthropic ideas were implemented in Sweden through the agency of translation. The present investigation of translation as a form of nineteenth-century social-reform activism takes the form of a case study of the Swedish translation of two texts by British social purity campaigner Ellice Hopkins (1836–1904). The purpose of the investigation is to explore how particula

Orbifold projection in supersymmetric QCD at N(f) ≤ N(c)

Supersymmetric orbifold projection of N = 1 SQCD with relatively small number of flavors (N(f) ≤ N(c)) is considered. The purpose is to check whether orbifolding commutes with the infrared limit. On the one hand, one considers the orbifold projection of SQCD and obtains the low-energy description of the resulting theory. On the other hand, one starts with the low-energy effective theory of the ori

Familial Mortality Risks in Patients With Heart Failure : A Swedish Sibling Study

Background The influence of familial factors on the prognosis of heart failure (HF) is unknown. This nationwide follow‐up study aimed to determine familial mortality risks of HF among Swedish siblings hospitalized for HF. Methods and Results We linked several Swedish nationwide registers for individuals aged 0 to 80 years. The study population consisted of 373 people hospitalized for HF for the

Dissonance reduction as emotion regulation: Attitude change is related to positive emotions in the induced compliance paradigm.

The aim of this study was to clarify how positive and negative emotions are related to the common attitude-change effect in cognitive dissonance research. Drawing on appraisal theories of emotion, and emotion-regulation research, we predicted that negative emotions would be inversely related to attitude change, whereas positive emotions would be positively related to attitude change in the inducedThe aim of this study was to clarify how positive and negative emotions are related to the common attitude-change effect in cognitive dissonance research. Drawing on appraisal theories of emotion, and emotion-regulation research, we predicted that negative emotions would be inversely related to attitude change, whereas positive emotions would be positively related to attitude change in the induced