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Involvement of End Users in a Navigation Aid Design Project

This paper describes the involvement of end users in a project aimed to create a navigation aid for older persons who have memory decline, which affects navigation skills, and thus their independence. Interviews, focus groups with “stick man scenarios” and shorter usability tests seemed to work well. An extended test where the users themselves were expected to use the system independently was not

Perception of Highlight Disparity at a Distance in Consumer Head-Mounted Displays

Stereo rendering for 3D displays and for virtual reality headsets provide several visual cues, including convergence angle and high- light disparity. The human visual system interprets these cues to estimate surface properties of the displayed environment. Naïve stereo rendering effectively doubles the computational burden of image synthesis, and thus it is desirable to reuse as many computa- tion

Global leadership - sustaining classic managerialism

This chapter critically discusses the currently celebrated and seemingly successful trend of global leadership. We claim that part of the answer to why global leadership has become so successful lies in how it is framed and presented as an all-embracing and intuitively good discourse closely aligned with the traditional leader-centred view on leadership in general. While this makes the discourse o

Migratory common blackbirds have lower innate immune function during autumn migration than resident conspecifics

Animals need awell-functioning immune systemto protect themselves againstpathogens. The immune system, however, is costlyand resource trade-offs withother demands exist. For migratory animals several (not mutually exclusive)hypotheses exist. First, migrants reduce immune function to be able to allocateresources to migration. Second, migrants boost immune function to cope withmore and/or novel path

Physiological role of TNF in mucosal immunology : Regulation of macrophage/dendritic cell function

Intestinal mononuclear phagocytes, comprising macrophages (MΦs) and dendritic cells (DCs), play important roles in the generation and the regulation of immune responses to intestinal antigens, and alterations in the development and/or the function of these cells are thought to contribute to the pathogenesis of inflammatory bowel disease. In this review, we discuss the role of tumor necrosis factor

Exploring the roles of university spin-offs in business networks

This paper identifies different university spin-off (USO) roles related to resource interaction among business parties. It does so by mapping how USOs become part of business networks in terms of their roles relative to other parties. The theoretical frame of reference focuses on roles and resource interaction based on an industrial network approach to business markets. The empirical research is b

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia

For many years, splenectomy has been used to treat immune thrombocytopenia (ITP), and this procedure benefits approximately two-thirds of the treated patients. Although splenectomy may raise platelet counts, antibody-coated platelets and cytotoxic T lymphocytes appear to persist or can change over time. To better understand how the spleen may affect anti-platelet immune responses, we used a murine

The nonhemostatic immune functions of platelets

Platelets are megakaryocyte-derived cellular fragments, which lack a nucleus and are the smallest circulating cells and are classically known to have a major role in supporting hemostasis. Apart from this well-established role, it is now becoming evident that platelets are also capable of conveying other important functions, such as during infection and inflammation. This paper will outline these

Move over Tregs, MDSCs are here

In this issue of Blood, Hou et al show the involvement of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of immune thrombocytopenia (ITP) and identify a novel mechanism by which high-dose dexamethasone (HD-DXM) promotes MDSC expansion and function and correlates with increased platelet counts.

Microparticles as biomarkers of lung disease : enumeration in biological fluids using lipid bilayer microspheres

Extracellular vesicles, specifically microparticles (MPs), are rapidly gaining attention for their capacity to act as biomarkers for diagnosis, prognosis, or responsiveness to therapy in lung disease, in keeping with the concept of precision medicine. However, MP analysis by high-sensitivity flow cytometry (FCM) is complicated by a lack of accurate means for MP enumeration. To address this gap, we

Bra regler men dålig tillämpning – en enkätstudie om pressetik och publicitetsskador

Med en enkätstudie undersöks i detta projekt hur effektivt de berörda anser att de medieetiska systemen ger upprättelse. Här är det värt att nämna att vi då arbetet inleddes bad PO-kansliet om hjälp att distribuera vår enkät till alla dem som stod bakom framgångsrika anmälningar under 2015. På så sätt skulle enkäten kunna genomföras samtidigt som anonymiteten i PO-systemet kunde

DN Debatt. ”Digitaliserad socialtjänst kan lösa framtidens behov”

Denna debattartikel argumenterar för att socialt arbete och socialtjänst behöver utvecklas i förhållande till digitalisering. Som ett led i ett samarbetsprojekt mellan Lunds universitet och Helsingborg stad, finansierat av både Vinnova och Helsingborg stad, skriver företrädare för både universitet och stad en debattartikel i DN. Hur kan socialtjänsten utvecklas med hjälp av digitalisering - nu och

Biology of polyphosphate-accumulating bacteria involved in enhanced biological phosphorus removal

Recent research on the process of biological phosphorus removal in lab-scale treatment systems has indicated that: (i) the development of an actively poly?-accumulating bacterial community after the introduction of an anaerobic period may take at least 4 months; (ii) up to 80% of all aerobic bacteria isolated from these communities are able to accumulate polyP; (iii) polyP synthesized by the bacte

Recent developments in the biochemistry and ecology of enhanced biological phosphorus removal

Most of the genes encoding the enzymes involved in polyP synthesis and degradation and in phosphate transport have been studied in various Gram-negative bacteria. Progress has also been made in studying the biochemicalmechanisms underlying the process of enhanced biological phosphorus removal (EBPR), in particular in lab-scale systems fed with acetate or acetate plus glucose as the sole carbon and

Green packaging development in theory and practice

In the light of the environmental challenges society is facing it is important thatboth products and their packaging systems are optimised from an environmental perspective. Previous research highlights that environmental optimisation of packaging requires an integrated assessment of product and packaging together.Theory on green packaging development (GPD) is comprehensive and there areexamples o

Late Cretaceous (Campanian) actinopterygian fishes from the Kristianstad Basin of southern Sweden

Although a diverse range of aquatic vertebrates are documented from the Upper Cretaceous (mid-Campanian) marine strata of the Kristianstad Basin in southern Sweden, only chondrichthyans and marine amniotes have been described in detail to date. In contrast, coeval actinopterygians are virtually unreported, yet their remains are extremely abundant at most sampled localities. A comprehensive assessm