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Background: Desmoplastic melanoma (DM) is a rare subtype, accounting for less than 5% of primary cutaneous invasive melanomas. DM often arises in chronically sun-exposed skin, in older individuals. While the incidence of cutaneous melanoma has increased globally, trends specific to DM are less documented and studies on survival outcomes for DM are inconsistent. Objectives: To study patient and tum

Metal fuels can be promising candidates as alternative energy sources and renewable energy carriers within the metal-fuel cycle. They feature high energy density, low environmental impact, and broad production and application. One challenge in metal particle combustion lies in its multi-physics complexity compared to traditional hydrocarbon fuels. This thesis intends to investigate the combustion

Denna rapport jämför två fall där Helsingborgs stad verkar för att bli mer cirkulär. Det ena är hur avfallsbolaget NSR (där staden är majoritetsägare) har utvecklat en produktionsanläggning och kompetenscentrum om biokol. Det andra är hur Stadsbyggnadskontoret, med Fastighetsförvaltningen, arbetar med att främja återbruk. Rapporten beskriver hur man i dessa två fall har skapat agendasättande relatDenna rapport jämför två fall där Helsingborgs stad verkar för att bli mer cirkulär. Det ena är hur avfallsbolaget NSR (där staden är majoritetsägare) har utvecklat en produktionsanläggning och kompetenscentrum om biokol. Det andra är hur Stadsbyggnadskontoret, med Fastighetsförvaltningen, arbetar med att främja återbruk. Rapporten beskriver hur man i dessa två fall har skapat agendasättande relat

Tool-based code review has been an established software engineering practice for at least a decade. However, while software development environments have improved significantly during this time with advanced features for code comprehension, refactoring, and AI support, code review tools have remained more static and are still centered around a two-way textual diff view with features similar to whe

A debated feature of civil society leadership is the (lack of) diversity among leaders. Another concern is the recruitment of leaders from the public and private sector. In this study we link these debates, analysing how civil society elite boundary crossing – that is, leaders from public and private sectors moving into elite positions in civil society – contributes to making the group of civil so

Accurate prediction of crack growth and strength in glued timber joints and components can be achieved by using cohesive laws in constitutive models. These laws represent the traction-separation relationship that measures the stress transmitted between crack faces in a cohesive zone, and can be obtained directly from experiments. However, studies on measuring the cohesive laws of wood adhesive bon

The paper provides an overview and preliminary results from ongoing research with the aim to evolve cross-laminated timber (CLT) into the next generation of Tailored Laminated Timber (TLT). This is done by exploring innovative concepts that optimize the mechanical performance, while simultaneously ensuring adherence to circular economy principles. The current study aims at investigating the potent

In previous years, substantial research has focused on walkability, primarily examining how the built environment affects walking behavior. However, these studies have predominantly defined walkability through physical and social factors, with limited exploration of its spatial dimension. This article seeks to address this gap by examining the spatiality of walkability through Lefebvre’s spatial tIn previous years, substantial research has focused on walkability, primarily examining how the built environment affects walking behavior. However, these studies have predominantly defined walkability through physical and social factors, with limited exploration of its spatial dimension. This article seeks to address this gap by examining the spatiality of walkability through Lefebvre’s spatial t

Groundwater hydraulics and aquifer processes are largely investigated using techniques that involve some kind of borehole test pumping. Such techniques are well established in the engineering and scientific community but are resource demanding. Time series analysis offer a collection of alternative methods that can be used to evaluate groundwater processes like recharge by using natural groundwate

Recording and analysing groundwater level data can reveal the nature and extension of groundwater processes like flow direction and recharge magnitude. The analyses can even indicate the influence of precipitation, evapotranspiration and runoff on the subsurface processes. However, such analyses are only possible when the recorded data cover relatively large periods of time at a suitable frequency

This study investigates the perception and understanding of climate-related risks among six energy-intensive and natural resource-based industry (ENRI) sectors using data from the CDP survey from 2020 to 2023. ENRI sectors, including fossil fuels; cement and concrete; chemicals; metallic smelting; refining; and forming; metallic mineral mining; and pulp and paper mills, are exposed to significant

The standard of proof at the International Court of Justice (ICJ) is a central, yet underexplored, aspect of its judicial decision-making. Although central in shaping both fact-establishment and judicial outcomes, the articulation and application of the standard of proof by the Court are marked by inconsistency and a lack of transparent justification. This inconsistency is often linked to an assumThe standard of proof at the International Court of Justice (ICJ) is a central, yet underexplored, aspect of its judicial decision-making. Although central in shaping both fact-establishment and judicial outcomes, the articulation and application of the standard of proof by the Court are marked by inconsistency and a lack of transparent justification. This inconsistency is often linked to an assum

The literature on ownership in healthcare lacks evidence from the primary care sector, where the traditional small-scale business model is increasingly complemented by larger practices owned by corporations or the government. We explore the role of ownership in primary care in relation to a core theme in health economics — the balance between fee-for-service and capitation remuneration. We study h

The cell is the fundamental unit of life and in multicellular animals, all cells are derived from stem cells. To understand how stem cell development may influence phenotypic evolution, this thesis studies a population of vertebrate stem cells known as neural crest cells (NCCs). With unparalleled potency and migratory behavior, NCCs affect many different traits spread over the entire vertebrate boThe cell is the fundamental unit of life and in multicellular animals, all cells are derived from stem cells. To understand how stem cell development may influence phenotypic evolution, this thesis studies a population of vertebrate stem cells known as neural crest cells (NCCs). With unparalleled potency and migratory behavior, NCCs affect many different traits spread over the entire vertebrate bo