Investigation of impurities in Supercritical Fluid Chromatography with Trapped Ion Mobility Spectrometry – Quadrupole / Time of Flight Mass Spectrometry
Introduction: Achieving and retaining a low background signal is essential for analytical techniques, especially for extremely accurate systems such as supercritical fluid chromatography (SFC) coupled with high-resolution mass spectrometry (HRMS) since the limits of detections are heavily dependent on the background signal. Background: A standard option to ensure a low background signal is the usa
