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Two time scales for self and collective diffusion near the critical point in a simple patchy model for proteins with floating bonds

Using dynamic Monte Carlo and Brownian dynamics, we investigate a floating bond model in which particles can bind through mobile bonds. The maximum number of bonds (here fixed to 4) can be tuned by appropriately choosing the repulsive, nonadditive interactions among bonds and particles. We compute the static and dynamic structure factor (intermediate scattering function) in the vicinity of the gas

Effects of the pocket cavity on heat transfer and fluid flow of the downstream outlet guide vane at different flow attacking angles

A pocket cavity is generated at the junction position of the low pressure turbine (LPT) and the outlet guide vane (OGV) in the rear part of a modern gas turbine jet engine. In the present study, a triangular pocket cavity is placed upstream of an OGV at different distances. The effects of the pocket cavity on heat transfer and fluid flow of the downstream OGV with different flow attack angles are

Acoustic phonons in nanowires probed by ultrafast pump-probe spectroscopy

The fascinating relationship between structure and property in nanowires has enabled a wealth of applications in photonics and electronics. The behavior of phonons in nanowires is also modified compared to their bulk counterparts. In this review, we provide an overview of the recent efforts to investigate the properties of acoustic phonons in nanowires using ultrafast optical methods. In particula

A minority-group of renal cell cancer patients with high infiltration of CD20+B-cells is associated with poor prognosis

Background: The role of B-lymphocytes in solid tumours is unclear. Tumour biology studies have implied both anti- and pro-tumoural effects and prognostic studies have mainly linked B-cells to increased survival. This study aimed to analyse the clinical relevance of B-lymphocytes in renal cell cancer (RCC), where information on the prognostic impact is lacking. Methods: Following immunohistochemist

Enhanced Direct Electron Transfer of Fructose Dehydrogenase Rationally Immobilized on a 2-Aminoanthracene Diazonium Cation Grafted Single-Walled Carbon Nanotube Based Electrode

In this paper, an efficient direct electron transfer (DET) reaction was achieved between fructose dehydrogenase (FDH) and a glassy-carbon electrode (GCE) upon which anthracene-modified single-walled carbon nanotubes were deposited. The SWCNTs were activated in situ with a diazonium salt synthesized through the reaction of 2-aminoanthracene with NaNO2 in acidic media (0.5 M HCl) for 5 min at 0 °C.

Urban experimentation & sustainability transitions

This special issue deals with various research questions regarding the impact of urban experimentation on transitions towards sustainability in different industries and sectors. Cities have been identified to play a vital role for sustainability transitions. Not only are they places with an increased urgency for change, but they also bring about many current sustainability initiatives and interven

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Volymen behandlar Roms betydelse för de skandinaviska konstnärerna under 1800-talet. Bidragen är fördelade i en del om bilden av Rom och Italien, en del om konstakademierna och studieresorna till Italien och en del om original och avgjutning av det klassiska skulpturarvet.

The Origin of Carbonate Veins Within the Sedimentary Cover and Igneous Rocks of the Cocos Ridge : Results From IODP Hole U1414A

Carbonate veins in the igneous basement and in the lithified sedimentary cover of the Cocos Ridge at International Ocean Discovery Program (IODP) Hole 344-U1414A reveal the hydrologic system and fluid-rock interactions. IODP Hole 344-U1414A was drilled on the northern flank of the Cocos Ridge and is situated 1 km seaward from the Middle America Trench offshore Costa Rica. Isotopic and elemental co

Temporal changes in abundance exhibit less spatial structure than abundance itself in North American birds

Species abundance is often spatially structured such that, within a species’ distribution, abundance peaks at one or more areas and declines from those points. Abundance may also increase or decrease over time, but the spatial structure of temporal changes in abundance has been infrequently examined. Here we use count data from the North American Breeding Bird Survey (BBS) to describe the spatial

CuInSe2 Quantum Dots Hybrid Hole Transfer Layer for Halide Perovskite Photodetectors

A novel hybrid hole transport layer (HTL) of CuInSe2 quantum dots (QDs)/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) was developed to enhance the performance of halide metal perovskite (MAPbI3)-based photodetectors. The introduction of CuInSe2 QDs not only improved the wettability of the PEDOT:PSS HTL for the growth of perovskite crystals but also facilitated the transportat

Mechanism and rate constants of the CH2 + CH2CO reactions in triplet and singlet states : A theoretical study

Ab initio and density functional CCSD(T)-F12/cc-pVQZ-f12//B2PLYPD3/6-311G** calculations have been performed to unravel the reaction mechanism of triplet and singlet methylene CH2 with ketene CH2CO. The computed potential energy diagrams and molecular properties have been then utilized in Rice–Ramsperger–Kassel–Marcus-Master Equation (RRKM-ME) calculations of the reaction rate constants and produc

Serum kidney injury molecule 1 and β2-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes

Aims/hypothesis: As part of the Surrogate Markers for Micro- and Macrovascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) programme we previously reported that large panels of biomarkers derived from three analytical platforms maximised prediction of progression of renal decline in type 2 diabetes. Here, we hypothesised that smaller (n ≤ 5), platform-specific combinations of biomarkers

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017 : a systematic analysis for the Global Burden of Disease Study 2017

BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be liv

Meniscal body extrusion and cartilage coverage in middle-aged and elderly without radiographic knee osteoarthritis

Objectives: To determine meniscal extrusion and cartilage coverage on magnetic resonance (MR) images and factors associated with these parameters in knees of middle-aged and elderly persons free from radiographic tibiofemoral osteoarthritis (OA). Methods: Seven hundred eighteen persons, free of radiographic tibiofemoral OA, aged 50–90 years from Framingham, MA, USA, were included. We measured meni

Binary black hole mergers from globular clusters : The impact of globular cluster properties

The dense environment of globular clusters (GCs) can facilitate the formation of binary black holes (BBHs), some of which can merge with gravitational waves within the age of the Universe. We have performed a survey of Monte Carlo simulations following the dynamical evolution of GCs with different masses, sizes, and binary fractions and explored the impact of the host GC properties on the formatio

Plasma markers of chronic low-grade inflammation in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration

Purpose: Ageing is the strongest predictor of neovascular age-related macular degeneration (AMD), where neuroinflammation is known to play a major role. Less is known about polypoidal choroidal vasculopathy (PCV), which is an important differential diagnosis to neovascular AMD. Here, we report plasma markers of inflammation with age (inflammaging) in patients with PCV, patients with neovascular AM