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The Effect of Unemployment, Inflation and Real Income Growth on Government Popularity in Sweden
Robot-assisted approach to cervical cancer (RACC) : An international multi-center, open-label randomized controlled trial
Background Radical hysterectomy with pelvic lymphadenectomy represents the standard treatment for early-stage cervical cancer. Results from a recent randomized controlled trial demonstrate that minimally invasive surgery is inferior to laparotomy with regards to disease-free and overall survival. Primary Objective To investigate the oncologic safety of robot-assisted surgery for early-stage cervic
On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies
Efficient and reliable sample delivery has remained one of the bottlenecks for serial crystallography experiments. Compared with other methods, fixed-target sample delivery offers the advantage of significantly reduced sample consumption and shorter data collection times owing to higher hit rates. Here, a new method of on-chip crystallization is reported which allows the efficient and reproducible
Dataset on multichannel connectivity and video transmission carried on commercial 3G/4G networks in southern Sweden
In this data article, we report real-world data on multichannel connectivity and videotransmission carried on commercial 3G/4G networks in the region of Skåne, southern Sweden. The data reported here complement the research article “Technical feasibility and ambulance nurses’ view of a digital telemedicine system in pre-hospital stroke care – A pilot study” (1). The dataset was originally collecte
Enter the Sensuous City
Spatial analysis of HIV-TB co-clustering in Uganda
BACKGROUND: Tuberculosis (TB) is the leading cause of death for individuals infected with Human immunodeficiency virus (HIV). Conversely, HIV is the most important risk factor in the progression of TB from the latent to the active status. In order to manage this double epidemic situation, an integrated approach that includes HIV management in TB patients was proposed by the World Health Organizati
Vulnerability and Resilience: Women’s Narratives of Forced Displacement from Abkhazia
Systematic evaluation of levodopa-carbidopa intestinal gel patient-responder characteristics
Levodopa-carbidopa intestinal gel (LCIG, carbidopa-levodopa enteral suspension in the United States) is a treatment option for advanced Parkinson's disease (PD) patients with motor fluctuations. The objective of this investigation was to identify the baseline characteristics predictive of treatment response, measured by improvement in motor symptom severity, in advanced PD patients treated with LC
Comparison of the yield of tuberculosis among contacts of multidrug-resistant and drug-sensitive tuberculosis patients in Ethiopia using GeneXpert as a primary diagnostic test.
Tracking in action space
The recognition of human actions such as pointing at objects ("Give me that...") is difficult because they ought to be recognized independent of scene parameters such as viewing direction. Furthermore, the parameters of the action, such as pointing direction, are important pieces of information. One common way to achieve recognition is by using 3D human body tracking followed by action recognition
Groundwater arsenic biogeochemistry - Key questions & use of tracers to understand arsenic-prone groundwater systems
Over 100,000,000 people worldwide are exposed to high arsenic groundwater utilised for drinking or cooking. The consequent global avoidable disease burden is estimated to be of the order of 100,000 avoidable deaths or more per annum from just direct exposures e i.e. excluding indirect exposure (from rice and other foods) and excluding morbidity. Notwithstanding 1000s of papers published on arsenic
Viewpoint and practical recommendations from a movement disorder specialist panel on objective measurement in the clinical management of Parkinson's disease
Motor aspects of Parkinson's disease, such as fluctuations and dyskinesia, can be reliably evaluated using a variety of "wearable" technologies, but practical guidance on objective measurement (OM) and the optimum use of these devices is lacking. Therefore, as a first step, a panel of movement disorder specialists met to provide guidance on how OM could be assessed and incorporated into clinical g
Use of indicators of standards of care to improve tuberculosis program management in Ethiopia
Disease stage dependency of motor and non-motor fluctuations in Parkinson's disease
Recent data suggested a decrease in non-motor fluctuations in late-stage Parkinson's disease (PD), but systematic data on non-motor fluctuations over the whole disease course are mainly lacking. We performed a meta-analysis of two studies with very similar cross-sectional cohort designs, namely the German multicenter Non Motor Fluctuation in PD study and the Swedish part of the European multicente
Ethiopia's experience on scaling up latent TB infection management for people living with HIV and under-five child household contacts of index TB patients.
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Patients with advanced Parkinson's disease and motor complications undergoing optimized oral therapy can significantly benefit from continuous intrajejunal levodopa/carbidopa infusion applied by means of a medication pump. However, this requires a correctly positioned PEG-J tube and finely adjusted pump settings. Although this method is a routine procedure in specialist centers, no standard proced
Nitric oxide (NO) - Production and regulation of insulin secretion in islets of freely fed and fasted mice
Production of nitric oxide through the action of nitric oxide synthase (NOS) has been detected in the islets of Langerhans. The inducible isoform of NOS (iNOS) is induced by cytokines and might contribute to the development of type-1 diabetes, while the constitutive isoform (cNOS) is thought to be implicated in the physiological regulation of insulin secretion. In the present study we have detecte
Non-oral Continuous Drug Delivery Techniques in Parkinson's Disease : For Whom, When, and How?
Continuous dopaminergic stimulation (CDS) has become one of the main concepts in present Parkinson's disease (PD) research. This is based on the assumption that CDS, or rather near CDS, is the normal striatal setting in a healthy individual. In PD, the degeneration of dopaminergic neurons leads to a reduced capacity to buffer dopamine, which could increase the vulnerability to a pulsatile administ
