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Extreme ultraviolet interferometry measurements with high-order harmonics

We demonstrate that high-order harmonics generated by short, intense laser pulses in gases provide an interesting radiation source for extreme ultraviolet interferometry, since they are tunable, coherent, of short pulse duration, and simple to manipulate. Harmonics from the 9th to the 15th are used to measure the thickness of an aluminum layer. The 11th harmonic is used to determine the spatial di

Large Eddy Simulation of Atomizing Sprays

Liquid-gas two-phase flows occur frequently in daily life, in nature e.g. falling rain drops or waves in the sea, and in industrial applications, e.g. fuel injection in Diesel engines or gas turbines. For many of these applications the interaction between liquid and gas is crucial for their efficient operation. In this work liquid-gas interaction is studied numerically, specifically for atomizing

Kick back and destroy the ride: Alcohol-related violence and associations with drinking patterns and delinquency in adolescence

AIM: To assess how drinking patterns and delinquency are associated with self-reported experiences of alcohol-related violence in an adolescent population. POPULATION AND RESEARCH DESIGN: Cross-sectional data were acquired from the Scania drug use survey 2005, consisting of 3847 students in 9th grade. Abstainers were omitted and 1873 responses analyzed, with binary and multi-variable logistic regr

Transfer Function Parameter Identification by Modified Relay Feedback

This paper proposes a transfer function parameter identification method, applicable to SISO systems of any order. Parameter identification is posed as a (non-convex) squared output error minimization problem, numerically solved utilizing Newton-Raphson iteration with back tracking line search. Focus lies on computing the cost function gradient and Hessian with respect to the parameter vector and o

The STAT3 Inhibitor Galiellalactone Effectively Reduces Tumor Growth and Metastatic Spread in an Orthotopic Xenograft Mouse Model of Prostate Cancer.

Signal transducer and activator of transcription 3 (STAT3) is known to be involved in the progression of prostate cancer (PCa) and is a key factor in drug resistance and tumor immunoescape. As a result, it represents a promising target for PCa therapy. We studied the effects of the STAT3 inhibitor galiellalactone (GL) on tumor growth and metastatic spread in vitro and in vivo. The effect of GL on

Importance of epoch length and registration time on accelerometer measurements in younger children.

AIM: The aim of this study was to investigate the effect of epoch length on accumulation of minutes of physical activity per day over a spectrum of intensities, and the effect that selection of number of hours of acceptable registration required per day had on number of days that were considered acceptable. METHODS: Participants were 696 children (369 boys and 327 girls) aged 6.7±0.4 yrs, from a

Kontrollen av brandskydd har allvarliga brister

Slutsatserna från en nyligen avslutad studie av ett fyrtiotal brandskyddsdokumentationer är oroväckande. Studien visar på allvarliga brister när det ska visas – verifieras – att samhällets krav på brandsäkerhet uppfyllts. Bristerna har inte heller uppmärksammats vid kontroll av brandskyddsdokumentationerna, vilket är både anmärkningsvärt och oroväckande.

Fast CMOS nonbinary divider and counter

A new kind of nonbinary CMOS divider and counter is presented. The divider directly gives a nonbinary dividing ratio without any decoder and, therefore, no speed degradation. They can be directly cascaded to form a nonbinary ripple chain and can be programmable. The principle is particularly useful for a nonbinary prescaler. A synchronous nonbinary counter using this principle is also presented. S

Signal transduction pathway profiling of individual tumor samples

Background Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to analyze tumor gene expression data from microarrays in the context of such pathways. Results We use pathways compiled from the TRANSPATH/TRANSFAC databases and the literature, and three publicly available cancer microarray da

Challenging the strategy paradigm within the paper packaging industry

Formulating and implementing a new strategy may be a challenging task, especially if it alters the way in which a company has operated and positioned itself before. This may be particularly true for companies within the forest industry, like manufacturers of paper packaging products, pursuing differentiated customer value and innovative solutions where, traditionally, success has been measured in

Long-term changes and impacts of hypoxia in Danish coastal waters

A 38-year record of bottom water dissolved oxygen concentrations in coastal marine ecosystems around Denmark (1965-2003) and a longer partially reconstructed record of total nitrogen (TN) inputs (1900-2003) were assembled to describe long-term patterns in hypoxia and anoxia. Interannual variations in bottom water oxygen concentrations were analyzed in relation to various explanatory variables (bot

The "beta-clasp" model of apolipoprotein A-I - A lipid-free solution structure determined by electron paramagnetic resonance spectroscopy.

Apolipoprotein A-I (apoA-I) is the major protein component of high density lipoproteins (HDL) and plays a central role in cholesterol metabolism. The lipid-free/lipid-poor form of apoA-I is the preferred substrate for the ATP-binding cassette transporter A1 (ABCA1). The interaction of apoA-I with ABCA1 leads to the formation of cholesterol laden high density lipoprotein (HDL) particles, a key step

Laparoscopic extraperitoneal inguinal hernia repair versus open mesh repair: long-term follow-up of a randomized controlled trial.

BACKGROUND: We have conducted a randomized controlled trial of totally extraperitoneal hernia repair (TEP) versus tension-free open repair (Lichtenstein repair); we have presented the results previously up to 1 year after the operation. The aim of this study was to compare patient outcome in both groups at a median follow-up of 7.3 years after operation. METHODS: Of 168 patients included in a pros