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Ansiktsuttrycket säger mer än ord. Är emotionell smitta via ansiktsuttryck det första steget mot empati

The hypotheses were based on conceiving of automatic mimicking as involved in emotional empathy. Mimicry reactions (EMG) in high- and low-empathy subjects were studied when subjects were exposed to pictures of angry or happy faces. The degree of correspondence between subjects’ facial EMG reactions and their self-reported feelings was compared. The comparisons were made at different stimulus expos

Moraxella catarrhalis-dependent tonsillar B cell activation does not lead to apoptosis but to vigorous proliferation resulting in nonspecific IgM production.

The respiratory pathogen Moraxella catarrhalis has a high affinity for human IgD and is mitogenic for peripheral blood B lymphocytes. Moraxella IgD-binding protein, which is a multifunctional outer membrane protein with adhesive properties, is responsible for the interaction. Previous experiments with the Ig-binding B cell superantigens protein A and protein L from Staphylococcus aureus and Peptos

Memory-based attentional biases: Anxiety is linked to threat avoidance.

The purpose of the present research was to examine if anxiety is linked to a memory-based attentional bias, in which attention to threat is thought to depend on implicit learning. Memory-based attentional biases were defined and also demonstrated in two experiments. A total of 168 university students were shown a pair of faces that varied in their emotional content (angry, neutral, and happy), wit

Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction

In this report we show that Tyr568 and Tyr570 are phosphorylated in vivo in the Kit/stem cell factor receptor (Kit/SCFR) following ligand-stimulation. By mutation of Tyr568 and Tyr570 to phenylalanine residues and expression of the mutated receptors in porcine aortic endothelial (PAE) cells, we could demonstrate a loss of activation of members of the Src family of tyrosine kinases when Tyr568 was

Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation.

OBJECTIVE: To investigate the significance and pathogenic potential of a highly conserved major type II collagen triple-helical epitope-specific antibody (U1; amino acids 494-504) in vivo and in vitro in patients with early rheumatoid arthritis (RA) and in experimental animal models of collagen-induced arthritis (CIA). METHODS: U1-specific antibodies in sera from patients with early RA (with or wi

Dielectric properties of porous cement mortar: fractal surface effects

We have studied the electrical properties of cement mortars in the frequency range 10-4-107 Hz, for different water contents. The admittance scales as a power law with an exponent of about 0.7 in a wide frequency range. This behaviour is interpreted in terms of polarization and diffusion at fractal pore surfaces. We obtain a fractal dimension of 2.4, which is in good agreement with adsorption isot

Determination of Radiative Lifetimes In the 3d(10)np(2)p Sequence of Neutral Copper By Time-resolved Vuv Laser-spectroscopy

Lifetimes in the 3d(10)np(2)P sequence in neutral copper were measured by time-resolved laser spectroscopy. Excitation from the ground state was performed with pulsed laser radiation in the; vuv spectral region, generated by resonant sum-difference four-wave mixing in krypton gas. The lifetimes were evaluated from recorded optical transients. For the np(2)P(J) states we find the following: tau(n =

HMGA2 and MDM2 expression in lipomatous tumors with partial, low-level amplification of sequences from the long arm of chromosome 12.

Ordinary lipomas are cytogenetically characterized primarily by simple balanced chromosome aberrations with stable morphologies, most of which affect chromosome segment, 12q13-15, where the HMGA2 gene plays a key pathogenetic role. Atypical lipomatous tumors (ALTs) display supernumerary ring or giant marker chromosomes with amplification of several genes including HMGA2 and MDM2. A study of HMGA2

Site-specific cancer deaths in cancer of unknown primary diagnosed with lymph node metastasis may reveal hidden primaries.

Cancer of unknown primary site (CUP) is a fatal cancer ranking among the five most common cancer deaths. CUP is diagnosed through metastases, which are limited to lymph nodes in some patients. Cause-specific survival data could guide the search for hidden primary tumors and help with therapeutic choices. The CUP patients were identified from the Swedish Cancer Registry between 1987 and 2008; 1444

Blood substitution and complement activation.

Complement activation was studied in 45 patients undergoing total hip arthroplasty under epidural anesthesia. The patients were randomly allocated to three groups. In Group I blood loss was replaced with microaggregate-poor erythrocyte concentrate (SAGM-ERC) plus 3% dextran-60 as plasma substitute, and postoperative analgesia was maintained with intramuscular ketobemidone. In Group II blood loss w

Evaluation of a tape-stripping technique for measuring dermal exposure to pyrene and benzo(a)pyrene.

Epidemiological studies have shown an increased incidence of cancer among workers occupationally exposed to polycyclic aromatic hydrocarbons (PAHs). As the dermal route is considered important for exposure to PAHs in the workplace, the aim of this study was to develop and evaluate a tape-stripping technique for monitoring dermal exposure to pyrene and benzo(a)pyrene. The tape-stripping method was

The Human Variome Project (HVP) 2009 Forum "Towards Establishing Standards".

The May 2009 Human Variome Project (HVP) Forum "Towards Establishing Standards" was a round table discussion attended by delegates from groups representing international efforts aimed at standardizing several aspects of the HVP: mutation nomenclature, description and annotation, clinical ontology, means to better characterize unclassified variants (UVs), and methods to capture mutations from diagn

Expression of Multiple Functional RNAs or Proteins from One Viral Vector.

In this chapter, we will cover the available design choices for enabling expression of two functional protein or RNA sequences from a single viral vector. Such vectors are very useful in the neuroscience-related field of neuronal control and modulation, e.g., using optogenetics or DREADDs, but are also desirable in applications of CRISPR/Cas9 in situ genome editing and more refined therapeutic app

The use of propofol sedation in a paediatric intensive care unit.

Background: The aim of this study was to prospectively evaluate and report the experience of the use of continuous intravenous propofol sedation in a paediatric intensive care unit (PICU). Methods: All children younger than 16 years who were admitted to the PICU at a University Hospital for slightly more than a year and received propofol infusion were included prospectively and data were recor

Family members' experiences of personal assistance given to a relative with disabilities.

Personal assistance is a type of home care common to many countries even though entitlement and legislative framework may vary from country to country. At present, there exists no knowledge about the family members' experiences of such assistance; therefore, the aim of this study was to investigate family members' experiences of personal assistance given to a relative of working age with a functio

Plasma homocysteine, brain imaging and cognition in older patients with mental illness.

BACKGROUND: Total plasma homocysteine (tHcy) concentration is elevated in older patients with mental illness, and patients with vascular disease have higher plasma tHcy concentration than patients without vascular disease. Plasma tHcy has been reported to be associated with cognitive functions. The mechanism by which plasma tHcy may influence cognitive functions is not clear. METHOD: We have inves

FACT: An Open-Label Randomized Phase III Study of Fulvestrant and Anastrozole in Combination Compared With Anastrozole Alone as First-Line Therapy for Patients With Receptor-Positive Postmenopausal Breast Cancer.

PURPOSE To compare the effect of therapy with anastrozole versus a combination of fulvestrant and anastrozole in women in first relapse of endocrine-responsive breast cancer. PATIENTS AND METHODS Postmenopausal women, or premenopausal women receiving a gonadotropin-releasing hormone agonist, with estrogen receptor- and/or progesterone receptor-positive disease at first relapse after primary trea

Estimation of Spherical Wave Coefficients from 3D Positioner Channel Measurements

Electromagnetic vector spherical waves have been used recently to model antenna-channel interaction and the available degrees of freedom in MIMO systems. However, there are no previous accounts of a method to estimate spherical wave coefficients from channel measurements. One approach for this, using a 3D positioner, is presented and analyzed in this letter. Measurement results are presented and d