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Toward clinical application of prompt gamma spectroscopy for in vivo monitoring of boron uptake in boron neutron capture therapy

In boron neutron capture therapy (BNCT) the absorbed dose to the tumor cells and healthy tissues depends critically on the boron uptake. Pronounced individual variations in the uptake patterns have been observed for two boron compounds currently used in clinical trials. This implies a high uncertainty in the determination of the boron dose component. Ln the present work a technique known as prompt

Dextran, gelatin, and hydroxyethyl starch do not affect permeability for albumin in cat skeletal muscle

OBJECTIVE: To evaluate the effects of the three commercially available colloid solutions, 6% dextran 70, 6% hydroxyethyl starch (HES) 200/0.5, and 3.5% urea-linked gelatin on permeability for human albumin in a skeletal muscle in vivo model by evaluating their effects on the reflection coefficient for albumin. DESIGN: Controlled laboratory study. SETTING: University research laboratory. SUBJECTS:

Experimental and simulated M-shell nickel spectra in the 14.4-18.0 nm region from magnetic fusion devices

Experimental M-shell nickel spectra in the 14.4-16.5 nm region from the JET tokamak (from both divertor and limiter configurations) and from the reversed field pinch RFX have been simulated. These spectra include lines from five ionization states, namely from K-like N-i9+ to P-like Ni13+ ions. For the JET limiter configuration the spectrum upper wavelength limit was higher (18.0 nm) and lines from

Pyrolysis-gas chromatography combined with simca pattern-recognition for classification of fruit-bodies of some ectomycorrhizal suillus species

Naturally grown fruit-bodies of Suillus luteus, S. bovinus and S. variegatus were subjected to Py-GC. The pyrograms obtained were statistically analysed and classified with a multivariate classification program (SIMCA). The class describing the S. bovinus pyrograms was significantly separated from both the S. luteus and the S. variegatus classes, while these two classes showed some over-lapping wh

Effects of a second mutant allele (V199I) at the PRKAG3 (RN) locus on carcass composition in pigs

The effect of a second mutant allele (V1991, here denoted rn*) at the PRKAG3 (RN) locus on carcass composition was determined in 334 pigs, entire males and females, from crosses between Swedish Hampshire (H) and Finnish Landrace (L) (H x LH; LH x H; LH x LH). Pigs were classified according to DNA test into the following PRKAG3 genotypes: RN-IRN- (23%), RN-/rn(-) (24%), RN-/rn* (33%), rn(+)/rn(+) (

Beyond the Controversy: A Study of African Theologies of Inculturation and Liberation

When Harry Sawyerr wrote his essay "What is African Theology?", published first in African Theological Journal, vol. 4 (1971), it appeared from its contents that he was making short comments about James Cone's Black theology that could have disappeared in the midst of more pressing African theological issues. Sawyerr's article was not primarily intended as a critique of Cone's Black theology; inst

Amperometric determination of acetate with a tri-enzyme based sensor

The present work describes a flow injection analysis system incorporating amperometric biosensors for acetate monitoring. Tri-enzyme-modified electrodes were fabricated by immobilizing acetate kinase (AK), pyruvate kinase (PK) and lactate dehydrogenase (LDH) into a poly(ethyleneglycole) diglycidyl ether (PEGDGE) film also containing Brilliant Cresyl Blue (BCB) as an electrochemical mediator. The c

Critical degrees of saturation at freezing of porous and brittle materials

This thesis is based on experimental work carried out during the period 1968-1972. The whole investigation is sponsored by the Swedish Council for Building Research and has been performed at the department of Building Materials at the Lund Institute of Technology. The thesis treats the problem frost resistance of building materials, a problem which is far from beeing solved despite much scientifi

Applications of Laser Based Measurements to Combustion Related Fluid Dynamics

This thesis is concerned with laser based techniques for the measurement of fluid dynamical properties and their application to combusting flowfields or flowfields related to combustion. As an introduction, the theory of turbulent flows and combustion is shortly presented. An overview of laser based measuring techniques is given. Next, seven papers are included. The main topic of papers 1 and 2 is

k(t)-factorization and CCFM: The solution for describing the hadronic final states everywhere?

The basic ideas of k(t)-factorization and CCFM parton evolution is discussed. The unintegrated gluon densities, obtained from CCFM fits to the proton structure function data at HERA are used to predict hadronic final state cross-sections like jet production at HERA, but also comparisons with recent measurements of heavy quark production at the Tevatron are presented. Finally, the k(t)-factorizatio

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (SNPs) in 1464 patients with T2D and 1467 matched controls, each characterized for measures of glucose metabolism, lipids, obesity, and blood pressure. With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed

F. P. Ramsey on Knowledge and Fallibilism

The paper deals mainly with two problems in the epistemology of Frank Plumpton Ramsey. One concerns his account of knowledge, the other his fallibilism. I argue that Ramsey failed to make room for the social aspect of knowledge and, furthermore, that he did not separate the fallibility of our view from its corrigibility. My positive proposal is to combine social reliabilism and corrigibilism with