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Your search for "swedish" yielded 92178 hits

Abnormal glucose tolerance and lung function in children with cystic fibrosis. Comparing oral glucose tolerance test and continuous glucose monitoring

BACKGROUND: Cystic fibrosis (CF) related diabetes (CFRD) is a common complication of CF. CFRD is associated with declining lung function even before its onset. Regular screening for CFRD using oral glucose tolerance test (OGTT) is recommended. Additionally, continuous glucose monitoring (CGM) has surfaced as a possible surveillance method, but evidence for its use and concordance with OGTT has not

Cesarean scar pregnancy : Reproductive outcome after robotic laparoscopic removal with simultaneous repair of the uterine defect

Objective: To describe perioperative adverse events, fertility and obstetric outcome, following a robot assisted laparoscopic approach for treating Cesarean scar pregnancies (CSP). Study Design: A retrospective case series of 14 consecutive women with a CSP and a wish for and attempts towards subsequent pregnancies, having undergone minimal invasive surgical treatment at two tertiary referral Swed

Interventions for nursing home residents with dysphagia—a scoping review

Oropharyngeal dysphagia is common in nursing home residents. The objective of this scoping review was to summarize and disseminate the findings from the literature on interventions for dysphagia in nursing home residents. Searches were conducted in four databases. The criteria for including the studies were nursing home residents, dysphagia, interventions, original research, published in English,

Robust Decision Analysis under Severe Uncertainty and Ambiguous Tradeoffs : An Invasive Species Case Study

Bayesian decision analysis is a useful method for risk management decisions, but is limited in its ability to consider severe uncertainty in knowledge, and value ambiguity in management objectives. We study the use of robust Bayesian decision analysis to handle problems where one or both of these issues arise. The robust Bayesian approach models severe uncertainty through bounds on probability dis

One crisis, one region, two municipalities: The geography of institutions and change agency in regional development paths

How do regions change their development path? We contribute to the growing literature on agency in regional development by combining it with a focus on the institutions that shape, support and constrain change agency in pursuit of different types of development paths. We answer the call for micro-level perspectives on regional economic change, using an in-depth and comparative case study approach.

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

The gut microbiome is shaped by diet and influences host metabolism; however, these links are complex and can be unique to each individual. We performed deep metagenomic sequencing of 1,203 gut microbiomes from 1,098 individuals enrolled in the Personalised Responses to Dietary Composition Trial (PREDICT 1) study, whose detailed long-term diet information, as well as hundreds of fasting and same-m

Tenecteplase in wake-up ischemic stroke trial : Protocol for a randomized-controlled trial

Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with acu

A population-based study on the effect of a routine second-look resection on survival in primary stage T1 bladder cancer

Objective: To assess the value of second-look resection (SLR) in stage T1 bladder cancer (BCa) with respect to progression-free survival (PFS), and also the secondary outcomes recurrence-free survival (RFS), bladder-cancer-specific survival (CSS), and cystectomy-free survival (CFS). Patients and methods: The study included 2456 patients diagnosed with stage T1 BCa 2004–2009 with 5-yr follow-up reg

Mortality in STEMI patients without standard modifiable risk factors : a sex-disaggregated analysis of SWEDEHEART registry data

Background: In cardiovascular disease, prevention strategies targeting standard modifiable cardiovascular risk factors (SMuRFs; hypertension, diabetes, hypercholesterolaemia, and smoking) are crucial; however, myocardial infarction in the absence of SMuRFs is not infrequent. The outcomes of individuals without SMuRFs are not well known. Methods: We retrospectively analysed adult patients with firs

The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

An important manifestation of severe COVID-19 is the ARDS-like lung injury that is associated with vascular endothelialitis, thrombosis, and angiogenesis. The intravascular innate immune system (IIIS), including the complement, contact, coagulation, and fibrinolysis systems, which is crucial for recognizing and eliminating microorganisms and debris in the body, is likely to be involved in the path

Molecular characterization of coxsackievirus a24v from feces and conjunctiva reveals epidemiological links

Coxsackievirus A24 variant (CVA24v), the main causative agent of acute hemorrhagic conjunctivitis (AHC), can be isolated from both the eyes and lower alimentary tract. However, the molecular features of CVA24v in feces is not well-documented. In this study, we compared the VP1 and 3C sequences of CVA24v strains isolated from feces during AHC epidemics in Cuba in 1997, 2003, and 2008–2009 with thos

Proteomic profiling reveals novel biomarkers and pathways in yype 2 diabetes risk

Recent advances in proteomic technologies have made high throughput profiling of low abundance proteins in large epidemiological cohorts increasingly feasible. We investigated whether aptamer-based proteomic profiling could identify biomarkers associated with future development of type 2 diabetes (T2DM) beyond known risk factors. We identified dozens of markers with highly significant associations

Antisense regulation of atrial natriuretic peptide expression

The cardiac hormone atrial natriuretic peptide (ANP) is a central regulator of blood volume and a therapeutic target in hypertension and heart failure. Enhanced ANP activity in such conditions through inhibition of the degradative enzyme neprilysin has shown clinical efficacy but is complicated by consequences of simultaneous accumulation of a heterogeneous array of other hormones. Targets for spe

The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells

The amplification of glucose-stimulated insulin secretion (GSIS) through incretin signaling is critical for maintaining physiological glucose levels. Incretins, like glucagon-like peptide 1 (GLP1), are a target of type 2 diabetes drugs aiming to enhance insulin secretion. Here we show that the protein phosphatase 1 inhibitor protein 1A (PPP1R1A), is expressed in β-cells and that its expression is

Performing to secure cultural hegemony : mediators' impact on the integration process

Purpose: The article takes its point of departure in the current labor market debate on immigration policy and attempts to explore the way private labor market mediators involved in the integration of immigrants contribute to reproducing cultural stereotypes reminiscent of colonial ideas. Design/methodology/approach: Findings are based on respondent-driven interviews with nine labor market mediato