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In our paper we address a gap in the literature, identified by Silverberg (2007), who claims that we miss an objective criteria for identifying leading sectors associated with technology-induced structural change and measuring their effects on functioning of the economy. In particular, we analyse the role of leading industries in labour reallocation across regions as a mechanism of smoothing regio
Virtual reality carries great promise to facilitate the building process. Some examples are the communication between architects and building companies, sellers and buyers or the community planners and the general public. It is often thought that in order to utilize the possibilities of VR, for example in the above-mentioned contexts, it is necessary to use full-fledged versions of VR including fo
MOTIVATION: Depletion of loss-of-function (LoF) mutations may provide a rank of genic functional intolerance and consequently susceptibility to disease.RESULTS: Here we have studied LoF mutations in 60 706 unrelated individuals and show that the most intolerant quartile of ranked genes is enriched in rare and early onset diseases and explains 87% of de novo haploinsufficient OMIM mutations, 17% mo
Frontotemporal dementia (FTD) and Alzheimer's disease (AD) are two frequent causes of dementia that share both clinical and neuropathological features. Common to both disorders are the neurofibrillary tangles consisting of aggregations of hyperphosphorylated tau protein. Recently, a number of different pathogenic mutations in the tau gene have been identified in families with FTD and parkinsonism
The Vel blood group antigen is expressed on the red blood cells of most individuals. Recently, we described that homozygosity for inactivating mutations in SMIM1 defines the rare Vel-negative phenotype. Still, Vel-positive individuals show great variability in Vel antigen expression, creating a risk for Vel blood typing errors and transfusion reactions. We fine-mapped the regulatory region located
Tumours displaying differentiation towards normal fat constitute the most common subgroup of soft tissue neoplasms. A series of such tumours was investigated by whole-exome sequencing followed by targeted ultra-deep sequencing. Eighty percent of angiolipomas, but not any other tumour type, displayed mutations in the protein kinase D2 (PRKD2) gene, typically in the part encoding the catalytic domai
Syfte: Undersöka hur stor andel av de aktierekommendationer som utfärdas för svenska aktiebolag som visar sig vara goda råd, ett år efter publiceringsdatum. Vidare analyseras ifall det råder någon specifik skillnad mellan köp- och säljrekommendationer. Metod: Kvantitativ studie med deduktiv ansats. Insamlade aktierekommendationer analyseras för att beräkna en eventuell abnormal avkastning. Result
Mundelsskadefrekvensen hos Fjädermygglarver har i tidigare studier används som bioindikator på sjöars eller vattendrags exponering för miljögifter. På uppdrag av Skellefteå kommun utfördes sommaren 2014 en undersökning av frekvensen mundelsskador hos Fjädermygglarver i Skellefteälven. Syftet med undersökningen är att få en inblick i hur exponerade Fjädermygglarver i dagsläget är för miljögifter i Larvae from the non-biting midge family Chironomidae have previously been demonstrated to be sensitive to environmental pollution in aquatic environments. Exposure to different contaminants has resulted in an increasing occurrence of deformities of the mouthparts in the larvae. Common pollutions which induce mouthpart deformitys are metals (such as Pb, Zn, Cd, Cu, Hg, Cr, Ni), pesticides and some
The aim of this study is to create an understanding of how caregivers at nursing homes in both the public and the private sector working conditions manifests itself from an organization theory perspective. The aim of this paper is to describe and analyze how the caregivers in elder care experience their working conditions and if the experiences differ depending on whether they work in the public o
As the society gets more and more dependent on electrical energy, it is highly desirable to ensurepower supply at all times. In case of events of natural disasters, simple technical faults or human mistakes, any power system or a large part of it can suffer a blackout. An electrical shutdown is a crisis situation where recovery should happen as quickly as possible. During the restoration after the
Minskad återvinning av avfall i anläggningsarbeten Återvinning i anläggningsändamål har minskat och folk i branschen tycker att processen tar för lång tid och att reglerna är för strikta. Detta leder till att mindre avfall återvinns och att mer avfall deponeras, än vad som skulle vara möjligt ur ett resurshushållningsperspektiv. För att spara på våra naturresurser och minska miljöpåverkan är de
En domstol är skyldig att genom s.k. materiell processledning verka för att ett mål blir tillräckligt utrett. Kravet gäller under hela rättegången och i alla instanser. Mitt syfte med denna uppsats är att fastställa hur långtgående materiell processledning i dispositiva tvistemål bör vara och vilka omständigheter som bör spela in när omfattningen av sådan processledning i enskilda fall bestäms. D
Different interests ascribe different meaning to the role of culture in urban regeneration and discourses are created. Previous research showed that successful examples of urban regeneration happened as culture-led bottom-up processes, where inhabitants had a supporting cooperation with the city administration. No strong evidence has been presented in previous research that culture has trickle-dow
Young children have been identified as particularly exposed to fires. This study aims at investigating pre-school children's level of knowledge about fire and evacuation and if the level of knowledge increases after an education. The aim has also been to present guidelines of how educational materials for children of that age should be designed. The work has been conducted by interviews with p
Denna kandidatuppsats undersöker implementeringsproblemet som kan uppstå i avståndet mellan Sveriges riksdag och den verkställande byråkratin. Frågeställningen besvaras främst med hjälp av de värden som presenteras i Dahls demokratiteori (2002) och Lundquists teorier om byråkratisk etik (1988 & 1998) tillsammans med de värden som återfinns i Regeringskansliets värdegrund för statliga tjänstemä
Denna uppsats redogör för hur arbetsgivarens skyldigheter skiljer sig åt vid uppsägning respektive avsked och analyserar på vilka bevekelsegrunder en arbetsgivare kan välja att avskeda istället för att säga upp. Vid både uppsägning och avsked föreligger samma formella skyldigheter samt en skyldighet att förhandla innan åtgärden vidtas. Arbetsgivaren har dock olika lång tid på sig att lämna underräThis essay will discuss how the responsibilities of the employer differ between termination and dismissal and will furthermore analyse the motives an employer can have in order to justify the use of dismissal instead of termination. Before terminating or dismissing an employee, the employer must in both cases observe the formal responsibilities as well as the obligation to negotiate. The differenc
Denna uppsats behandlar förekomsten av rumslig autokorrelation i residualer till paneldatamodeller med tvåvägsfel. Tre modelltyper undersöks: den linjära paneldatamodellen, en dynamisk paneldatamodell och en spatial paneldatamodell. Ett känt resultat för den linjära modellen, att minsta kvadrat-skattaren tillämpad på oberoende observationer resulterar i en rumslig korrelation i residualserien varsThis thesis examines the spatial autocorrelation in residuals of two-way error panel data models. Three types of models are examined: the standard linear panel data model, the dynamic panel data model, and the spatial lag panel data model. A known theoretical result for the linear model, that the within estimator applied to independent observations results in a spatial correlation in the residuals
