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Who Needs the Classics? - On the Relevance of Classical Legal Sociology for the Study of Current Social and Legal Problems

What do we gain from labeling certain norms of social organization law? This question provides the backdrop against which this chapter will examine the works of Leon Petrażycki and Eugen Ehrlich, two of the founders of legal sociology who devised concepts of law broader than state law. In the course of this examination we shall also assess the relevance of Petrażycki’s 'intuitive law' and Ehrlich’

Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1

Heparan sulfate 3-O-sulfotransferase transfers sulfate to the 3-OH position of a glucosamine residue of heparan sulfate (HS) to form 3-O-sulfated HS. The 3-O-sulfated glucosamine residue contributes to two important biological functions of HS: binding to antithrombin and thereby carrying anticoagulant activity, and binding to herpes simplex viral envelope glycoprotein D to serve as an entry recept

Activation of Hormone-sensitive Lipase Requires Two Steps, Protein Phosphorylation and Binding to the PAT-1 Domain of Lipid Droplet Coat Proteins

Lipolysis is an important metabolic pathway controlling energy homeostasis through degradation of triglycerides stored in lipid droplets and release of fatty acids. Lipid droplets of mammalian cells are coated with one or more members of the PAT protein family, which serve important functions in regulating lipolysis. In this study, we investigate the mechanisms by which PAT family members, perilip

Modelling Time-Dependent Effects for Segmentally Constructed Prestressed Concrete Bridges

Tidsberoende effekter, såsom krypning, krympning och stålrelaxation, är ofta svåra att prediktera när det kommer till förspända betongkonstruktioner. Krypning som ett fenomen är komplicerat och förenklas därför i gällande byggnormer (Eurocode), för att underlätta konstruktörens arbete. När det gäller etappvis spännarmerade betongbroar har dessa förenklingar visat sig ge felaktiga prognoser av de tLong-term effects, such as creep, shrinkage, and steel relaxation, are often difficult to predict for prestressed concrete structures. Creep as a phenomenon is complicated to describe and is therefore simplified in the current building standards, to better accommodate the designer. When dealing with segmentally constructed prestressed concrete bridges, these simplifications have shown to provide i

Utanför boxen : om arkivariers syn på föremål i kommunarkiv

Outside the box. On archivists' views on objects in municipal archives Historically objects in archives and objects as "documents" have been discussed for a long time. The focus of the discussion has generally been on defining what is a document, and what is not, and later what is in turn an act and thus belongs in the archive, and what does not. An object is generally not defined a

Land Matters : Agrofuels, Unequal Exchange, and Appropriation of Ecological Space

As a global society we are entering an era where land areas and land-based resources are coming to the fore once again for capital accumulation and economic growth, for the first time since the end of the 18th century when Malthus forecasted a contradiction between population growth and agricultural output. That constraint on economic growth, imposed by limited land areas, was overcome by the comb

Common themes and challenges in hemophilia care : a multinational perspective

OBJECTIVE: To identify ways that provision of hemophilia care can be maximized at the local level, irrespective of available resources or cultural or geographic challenges.METHODS: The SHIELD group used its multinational experience to share examples of local initiatives that have been employed to deliver optimal hemophilia care.RESULTS: The examples were reviewed and categorized into four key them

The risk of carbon leakage in global climate agreements

Although climate change and international trade are interdependent, policy-makers often address the two topics separately. This may inhibit progress at the intersection of climate change and trade and could present a serious constraint for global climate action. One key risk is carbon leakage through emission outsourcing, i.e. reductions in emissions in countries with rigorous climate policies bei

Phasing out coal for 2 °C target requires worldwide replication of most ambitious national plans despite security and fairness concerns

Ending the use of unabated coal power is a key climate change mitigation measure. However, we do not know how fast it is feasible to phase-out coal on the global scale. Historical experience of individual countries indicates feasible coal phase-out rates, but can these be upscaled to the global level and accelerated by deliberate action? To answer this question, we analyse 72 national coal power p

Evaluating the added value of multi-variable calibration of SWAT with remotely sensed evapotranspiration data for improving hydrological modeling

Hydrological processes in a watershed consist of multiple sub-processes (such as plant growth, evapotranspiration, water yield, and soil–water balance) that have complex interactions. The common practice of calibrating hydrological models against only a single variable (e.g., streamflow) can lead to parameter uncertainty (also known as equifinality), resulting in significant uncertainties in the r

Soil Organic Carbon Stocks Depend Differently on Physicochemical Features in Subtropical Seasonally Flooded Wetland and Non-flooded Shoreland Forest

In recent years, an increasing number of ecosystems are threatened by seasonal flooding, changing non-flooded shoreland (NF) into seasonally flooded wetland (SF), but the consequences of this hydrological change for soil organic carbon (SOC) dynamics remain unknown. In this study, we investigated how the SOC content was determined by flooding duration and soil physicochemical variables in adjacent

Intelligent Monitoring Applications of Landslide Disaster Knowledge Graphs Based on ChatGLM2

Over the years, the field of landslide disaster research has amassed a wealth of data and specialized knowledge. However, these resources originate from a wide array of sources and often feature complex data structures, highlighting a persistent lack of methods to integrate multi-source, heterogeneous data. Traditional landslide monitoring methods typically focus on singular monitoring targets and

Sex and gender publications in brain health : a mapping review of the Asia-Pacific region

INTRODUCTION: Reporting of sex and gender analysis in medical research has been shown to improve quality of the science and ensures findings are applicable to women and men. There is conflicting evidence on whether efforts by funding agencies and medical journals to encourage reporting of sex and gender analysis has resulted in tangible improvements. This study mapped the inclusion of sex and gend

Greenhouse Gas Emissions and Energy Payback Time for multi- and mono-Si Photovoltaic Systems - A Study on Solar Energy from Photovoltaic Systems Located in Sweden

Solceller – en miljövänlig energikälla? Miljöförstöring i form av växthusgasutsläpp är en gigantisk utmaning som mänskligheten står inför och vi måste agera NU! Solceller innebär en fantastisk möjlighet att utvinna stora mängder “ren” energi från solen. Men hur miljövänliga är egentligen solceller och är det ett effektivt alternativ i Sverige? Varje timme träffas Jorden av tillräckligt mycket eClimate change is one of the greatest environmental challenges at the present time and is currently an issue affecting the entire global population. Alternative renewable energy sources are vital to be able to deal with this challenge. Solar energy is one of the most promising renewable energy sources and is therefore also one of the fastest growing industries in this field. However, solar energy

Wag the WeiWei - A US boot in the Asian door

The growing interdependence and interconnectedness of the global community set the pace and frame for the evolution of foreign policy. Diplomacy formerly being the reserve of international communication has consequently been forced to change and branch out. This essay attempts to view these changes and their context at the example of US foreign policy in Pacific Asia. Both hard power translating i

En framtida IS-tribunal – tomma ord eller en reell möjlighet?

Islamiska Staten har de senaste fem åren orsakat oerhört mycket smärta och sorg. Krigsförbrytelser, brott mot mänskligheten och folkmord ska ha begåtts i de områden rörelsen kontrollerat i Irak och Syrien. Nu när kalifatets sista fästen besegrats står det internationella samfundet inför en ny utmaning; hur och var ska de ansvariga individerna straffas? Vissa politiker har numera hävdat att en IS-tDuring the past five years, the Islamic State has been responsible for a large amount of pain and suffering. War crimes, crimes against humanity and genocide have been committed in the areas the group controlled in Iraq and Syria. Now as the Kalifate’s last strongholds have been defeated, the international community stands before a new task; how and where shall the individuals responsible be punis