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Testing the effect of site selection and parameter setting on REVEALS-model estimates of plant abundance using the Czech Quaternary Palynological Database

REVEALS-based quantitative reconstruction of Holocene vegetation cover (expressed in plant functional types. PFTs) is used in the LANDCLIM project to assess the effect of human-induced land-cover change on past climate in NW Europe. Using the Czech Quaternary Pollen Database, this case study evaluates the extent to which selection of data and input parameters for the REVEALS model applications wou

The effect of the North Atlantic Oscillation on the Iraqi climate 1982-2000

In this study, we have analyzed the spatial and temporal correlation between the North Atlantic Oscillation (NAO) and the climate in Iraq, with a focus on precipitation, temperature, and number of Mediterranean cyclones. It was found that the influence of the NAO varies per climate indicator. For example, the influence is greater on precipitation than on temperature. One conclusion of the study is

Multiple mechanisms of MYCN dysregulation in Wilms tumour.

Genomic gain of the proto-oncogene transcription factor gene MYCN is associated with poor prognosis in several childhood cancers. Here we present a comprehensive copy number analysis of MYCN in Wilms tumour (WT), demonstrating that gain of this gene is associated with anaplasia and with poorer relapse-free and overall survival, independent of histology. Using whole exome and gene-specific sequenci

Patterns of Phenotypic Divergence in Wing Covariance Structure of Calopterygid Damselflies

Comparing species differences in covariance patterns of traits subject to divergent selection pressures can increase our understanding to the mechanisms of phenotypic divergence. Different species of calopterygid damselflies have diverged in the melanized wing patch of males. This trait serves multiple ecological functions and has behavioral consequences in terms of sexual selection, interspecific

Drive current and threshold voltage control in vertical InAs wrap-gate transistors

Results on fabrication and DC-characterisation of vertical InAs nanowire wrap-gate field-effect transistor arrays with a gate length of 50 nm are presented. Each nanowire array was processed into a transistor with a systematic variation in a number of wires and wire diameter over the sample. Extensive studies have been performed on the influence of wire number and diameter on the transistor charac

Performance per What?

In this short note, we argue that performance per watt, which is often cited in the graphics hardware industry, is not a particularly useful unit for power efficiency in scientific and engineering discussions. We argue that joules per task and watts are more reasonable units. We show a concrete example where nanojoules per pixel is much more intuitive, easier to compute aggregate statistics from,

Fixed or loose? Dichotomy in RSA data for cemented cups

Background and purpose Roentgen stereometric analysis (RSA) cannot discern whether a single prosthesis is fixed or migrating below the detection level. Samples of patients usually show migration values that appear to be continuously distributed. Is there such continuity, or is there a dichotomy between stable and migrating prostheses? The hypothesis of a dichotomy has, to our knowledge, not been t

Injuries in Special Transport Services – situations and risk levels involving wheelchair users

Previous research has shown that wheelchair-seated passengers using special transportation services (STS) have been injured without being involved in a vehicle crash. In order to estimate incident rate and societal costs for these vehicle-related injuries, the focus needs to be adjusted towards a traveler/incident-oriented perspective. The aim of the project was to utilize such a perspective, rela

Do We Need a Distinction between Arguments and Adjuncts? Evidence from Psycholinguistic Studies of Comprehension

Within both psycholinguistic theories of parsing and formal theories of syntax, a distinction between arguments and adjuncts is central to some theories, while minimized or denied by others. Even for theories that deem the argument/ adjunct distinction important, the exact nature of the distinction has been difficult to characterize. In this article, we review the psycholinguistic evidence for an

ThermOS: System Support for Dynamic Thermal Management of Chip Multi-Processors

Constraining the temperature of computing systems has become a dominant design aspect. The supply voltage decrease has lost its pace even though the feature size is shrinking constantly. This results in an increased number of transistors per unit of area and hence a growing power density. Researchers started investigating dynamic thermal management techniques to trade-off performance for energy co

C/EBPβ expression is an independent predictor of overall survival in breast cancer patients by MHCII/CD4-dependent mechanism of metastasis formation.

CCAAT-enhancer binding protein β (C/EBPβ) is a transcription factor that has a critical role in mammary gland development and breast cancer progression. Loss of C/EBPβ increases metastatic dissemination of mouse mammary tumor cells. However, the mechanism by which C/EBPβ expression affects metastasis formation remains unknown. This study aims at determining the relationship between C/EBPβ and surv

A gradient-enhanced large-deformation continuum damage model for fibre-reinforced materials

A non-local gradient-based damage formulation within a geometrically non-linear setting is presented. The hyperelastic constitutive response at local material point level is governed by a strain energy which is additively composed of an isotropic matrix and of an anisotropic fibre-reinforced material, respectively. The inelastic constitutive response is governed by a scalar [1–d]-type damage formu

Clinical factors and outcome in T-cell lymphoma: a population-based perspective

The heterogeneous group of T-cell lymphomas consist mostly of aggressive diseasess, with generally unfavourable outcome compared to aggressive B-cell lymphomas following similar therapy. This thesis focus on outcome and risk factors for inferior survival, in an unselected population-based cohort of T-cell lymphoma patients. In the first study, outcome of the precursor malignancy T-cell Lymphoblast

Endograft Repair of Complicated Acute Type B Aortic Dissections

Objectives: This study aims to assess patient outcomes and aortic remodelling following coverage of the proximal entry tear with an endograft in complicated acute type B aortic dissections (caTBADs). Material and methods: All patients with caTBAD treated with a thoracic endograft in three high-volume vascular centres were retrospectively studied. Inclusion criteria were branch-vessel malperfusion,

Plasma phospholipid fatty acid concentrations and risk of gastric adenocarcinomas in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)

Background: Epidemiologic data suggest that diet is a risk factor in the etiology of gastric cancer. However, the role of dietary fatty acids, a modifiable risk factor, remains relatively unexplored. Objective: The objective of this study was to determine the association of plasma phospholipid fatty acid concentrations, as biomarkers of exogenous and endogenously derived fatty acids, with the risk