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Different assessments of immunohistochemically stained Ki-67 and hTERT in glioblastoma multiforme yield variable results: a study with reference to survival prognosis.

OBJECTIVE: To investigate a marker of tumor proliferation, Ki-67, and telomerase expression in glioblastoma multiforme and to compare the results of different mainly quantitative assessments, in relation to age and survival rates. METHODS: Immunohistochemical stainings of Ki-67 and hTERT were evaluated in 39 formaldehyde-fixed, paraffin-embedded surgical samples of glioblastoma multiforme diagnose

Introducing and developing a Product-Service System (PSS) concept in Sweden

Business challenges today are becoming more numerous, and more urgent. Many companies are expanding beyond their traditional product and market boundaries, while others are forming new alliances or outsourcing supporting functions to other producers. The concept of product-service system (PSS), analysed in this study, has the potential to improve companies’ competitiveness and provide new business

Improvement of dyskinesias with l-dopa infusion in advanced Parkinson's disease.

We wanted to investigate whether continuous intrajejunal levodopa-carbidopa intestinal gel (LCIG) therapy has an antidyskinetic effect in patients with Parkinson's disease (PD) and troublesome dyskinesias. We also sought to examine the effect of LCIG therapy on motor function and health-related quality of life (HRQoL).

Values Compared

Gert (2004) has suggested that several different types of value relations, including parity, can be clearly distinguished from each other if one interprets value comparisons as normative assessments of preference, while allowing for two levels of normativity - requirement and permission. While this basic idea is attractive, the particular modeling Gert makes use of is flawed. This paper presents a

History of depression prior to Alzheimer's disease and vascular dementia verified post-mortem.

The aim of this study was to analyze the medical history, with regards to previous remote depression, in patients with neuropathologically verified Alzheimer's disease (AD), vascular dementia (VaD) and mixed AD/VaD. The 201 patients included (115 AD, 44 VaD and 42 mixed AD/VaD) had been referred to the Psychogeriatric/Psychiatric Department, Lund University Hospital, for psychogeriatric investigat