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This article is a revised version of the inaugural lecture delivered on 5 October2023, on the occasion of the author's appointment as Professor of History of Religions at Lund University. It opens by depicting fundamental changes in the study of the history of religions in the twentieth century, followed by biographical notes, including her research on lay Buddhism in urban Taiwan, the emphasis on

Exposure to antibiotics and risk of latent autoimmune diabetes in adults and type 2 diabetes : results from a Swedish case–control study (ESTRID) and the Norwegian HUNT study

Aims/hypothesis: Some studies find an increased risk of type 1 diabetes in children exposed to antibiotics. We investigated if exposure to antibiotics increases the risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes. Methods: We used data from a Swedish case–control study (Epidemiological Study of Risk Factors for LADA and Type 2 Diabetes [ESTRID]: LADA, n=597; type 2 diabetes

Grain size control in quasi-two-dimensional perovskite thin film via intermediate phase engineering for efficient bound exciton generation

Quasi-two dimensional (2D) perovskites have emerged as a promising class of materials due to their remarkable photoluminescence efficiency, which stems from their exceptionally high exciton binding energies. The spatial confinement of excitons within smaller grain sizes could enhance the formation of biexcitons leading to higher radiative recombination efficiency. However, the synthesis of high-qu

A Trojan horse for climate policy: Assessing carbon lock-ins through the Carbon Capture and Storage-Hydrogen-Nexus in Europe

The global energy landscape is entrenched in fossil fuels, shaping modern life profoundly. Germany, a prominent example, grapples with transitioning from its fossil-fuelled infrastructure despite governmental support for decarbonization. Carbon capture and storage (CCS) and hydrogen appear as crucial tools in this transition. A recent partnership between Germany and Norway seeks to leverage Norway

International Education and Transnational Education Corporations

A major development in international schools since the first decade of the 21st century is the growth of global firms operating revenue-oriented schools. Whereas international schools were once community organizations serving the needs of expatriate communities, the landscape has been transformed into an education industry. Transnational corporations and revenue-oriented nonprofits have acquired s

Evaluating the Applicability of a Real-Time Highly Oxygenated Organic Molecule (HOM)-Based Indicator for Ozone Formation Sensitivity at a Boreal Forest Station

Ground-level ozone (O3), formed via complex photochemistry involving nitrogen oxides (NOx) and volatile organic compounds (VOCs), is a critical secondary pollutant and oxidant. Therefore, understanding whether the formation of O3 is NOx- or VOC-limited is essential for effective air quality management. Recently, we demonstrated that the distribution of highly oxygenated organic molecules (HOMs) ca

Behavioral manifestations of executive functioning in Swedish youth with ADHD, autism, and psychiatric comorbidity: a comparative analysis with community controls

While several rating scales reliably and cost-effectively assess behavioral executive functioning (EF) in youths with neurodevelopmental disorders (NDDs), questions remain about the impact of comorbidities and dual NDDs on EF as measured by these scales in clinical samples. This study compared behavioral EF profiles among youths with NDDs, both with and without psychiatric comorbidities, non-NDDs

Microglia degrade Alzheimer's amyloid-beta deposits extracellularly via digestive exophagy

How microglia digest Alzheimer's fibrillar amyloid-beta (Aβ) plaques that are too large to be phagocytosed is not well understood. Here, we show that primary microglial cells create acidic extracellular compartments, lysosomal synapses, on model plaques and digest them with exocytosed lysosomal enzymes. This mechanism, called digestive exophagy, is confirmed by electron microscopy in 5xFAD mouse b

Expanding Choreography through Everyday Movement in the Work of plan b

This book arises from the shared interest in practices of writing of artists and scholars in the field of performance, dance, and visual arts. For all authors writing is - in various forms and to different ends - an essential part of their work: as a movement practice and a mode of self-reflection, an aesthetic and epistemic practice. The different approaches converge in the idea of an "expanded w

Transforming Personal Daily GPS Data Through Performances: Movement, Memory and Time

This thesis examines three plan b performance pieces, which are all based on a long-term practice of recording GPS data daily (15 years for me at time of writing). The works comprise different performative processes to materialise the data through public drawing, narrating and collective knotting. Each of the pieces is related to the respective central themes of movement, memory and time. Through

Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis

CysK1 and CysK2 are two members of the cysteine/S-sulfocysteine synthase family in Mycobacterium tuberculosis, responsible for the de novo biosynthesis of L-cysteine, which is subsequently used as a building block for mycothiol. This metabolite is the first line defense of this pathogen against reactive oxygen and nitrogen species released by host macrophages after phagocytosis. In a previous medi

Nonprojective Bell-state measurements

The Bell-state measurement (BSM) is the projection of two qubits onto four orthogonal maximally entangled states. Here we first propose how to appropriately define more general BSMs, which have more than four possible outcomes, and then study whether they exist in quantum theory. We observe that nonprojective BSMs can be defined in a systematic way in terms of equiangular tight frames of maximally

RipD (Rv1566c) from mycobacterium tuberculosis : Adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function

Enzymes carrying NlpC/p60 domains, for instance RipA and RipB from Mycobacterium tuberculosis, are bacterial peptidoglycan hydrolases that cleave the peptide stems and contribute to cellwall remodelling during cell division.Amember of this protein family, RipD (Rv1566c) from M. tuberculosis described in the present study, displays sequence alterations in the NlpC/p60 catalytic triad and carries a

Quantitative flow ratio will supplant wire-based physiological indices : pros and cons

Quantitative flow ratio (QFR) represents a physiological index derived from angiography through three-dimensional (3D) quantitative coronary analysis. When compared to coronary angiography, QFR showed better performance both for guiding percutaneous coronary intervention (PCI) in case of intermediate coronary lesions and for optimising PCI results. In addition, QFR showed good diagnostic agreement

Microbiome–metabolite linkages drive greenhouse gas dynamics over a permafrost thaw gradient

Interactions between microbiomes and metabolites play crucial roles in the environment, yet how these interactions drive greenhouse gas emissions during ecosystem changes remains unclear. Here we analysed microbial and metabolite composition across a permafrost thaw gradient in Stordalen Mire, Sweden, using paired genome-resolved metagenomics and high-resolution Fourier transform ion cyclotron res

Grain alignment in hexaferrite permanent magnets by compaction at room and elevated temperatures

Shape-controlled precursors enable grain alignment without using an applied magnetic field in the permanent magnet material strontium hexaferrite. The effect is investigated by conducting four series of experiments using different compaction methods: two cold and two hot compactions. The hypothesis is that magnetic short-circuiting will diminish the grain alignment (texture) in cold compacted samp

Intensive early and sustained lowering of non–high-density lipoprotein cholesterol after myocardial infarction and prognosis : the SWEDEHEART registry

Background and Non–HDL-C provides an estimate of lipid-associated risk and is a secondary treatment target after myocardial infarction Aims (MI). The aim was to study the relationship between non–HDL-C levels after MI and risk of adverse outcomes. Methods From the SWEDEHEART registry, 56 262 patients with MI were included. Outcomes were major adverse cardiovascular event (MACE: death, MI, and isch

Review article : Drought as a continuum – memory effects in interlinked hydrological, ecological, and social systems

Droughts are often long-lasting phenomena, without a distinct start or end and with impacts cascading across sectors and systems, creating long-term legacies. Nevertheless, our current perceptions and management of droughts and their impacts are often event-based, which can limit the effective assessment of drought risks and reduction of drought impacts. Here, we advocate for changing this perspec

Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B.

Background Fidanacogene elaparvovec, an adeno-associated virus (AAV) gene-therapy vector for hemophilia B containing a high-activity human factor IX variant (FIX-R338L/FIX-Padua), was associated with sustained factor IX activity in a phase 1-2a study. Methods We conducted a phase 3 open-label study of fidanacogene elaparvovec at a dose of 5×1011 vector genome copies per kilogram of body weight. Me