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In recent years, tier‐two fashion countries have been making gains in the global fashion industry, with hip young brands, buzz‐worthy fashion weeks and export‐oriented designers. The Canadian fashion industry, on the other hand, continues to fall behind and instead has experienced recent high‐profile closures of leading domestic fashion names. This paper explores why this is the case by considerin

This paper explores a widely employed instrument of regional innovation policy: the innovation incubator. It proposes that incubation approaches are moving away from a ‘traditional’ approach strongly premised on physical infrastructure and high-technology, to a more interactive, participatory and social mode of innovation, in line with broader developments in innovation policy and theory. To pract

Universities and economic development in lagging regions: ‘triple helix’ policy in Wales. Regional Studies. This paper considers the applicability and relevance of triple helix-based policy and theory, in the weaker region context of Wales, where the success of such approaches has been questionable. It calls for a broader appreciation of the roles of universities in weaker regions beyond a narrow

As the social and economic landscape changes, universities are coming under growing pressure to contribute to the economic development of their localities. This paper explores the increasing trends towards universities as key actors in the governance of regional economic development through activities to support economic and entrepreneurship development in their regions. A case study is presented

This paper explores the translation and implementation of Smart Specialisation in Wales. It finds that rather than taking a new approach to innovation policy, Welsh policy-makers are following a largely cluster-based rationale, which omits the important entrepreneurial discovery process to identify the real strengths of the region. The fresh idea presented by this paper is that a replication of pa

This paper develops a framework for analysing the role of innovation policy in regional innovation system (RIS) development. It specifically focuses on the influence of policy on a set of enabling conditions for RIS that have not been taken fully into account in previous innovation policy studies. Drawing on relevant literature on innovation systems, such as innovation policy, triple helix and pol

Changing patterns of economic activity and their consequential impacts on rates of development have brought competitiveness to the top of many political and policy-making agendas. Ensuring that regional competitiveness is retained and enhanced is a common concern across the globe, although the nature of these concerns may differ according to past histories and future expectations (Huggins et al.,

This chapter analyses the roles and activities of multinational companies (MNCs) in an entrepreneurial ecosystem (EE) and local start-up incubation. Drawing from literature regarding EEs and incubation policy, we present an example of a type of intervention under-theorized to date: incubation efforts stemming from MNCs rather than government or universities. Presenting the case of Microsoft Innova

Recension av Volker Weidermann, München 1918. När författare och drömmare tog makten.

Fertilization is a common approach to increase or sustain soil fertility, but its impact on microbial biomass and community structure remains controversial, particularly in paddy soils. In this study, we investigated the effect of different long-term fertilization strategies, beginning in 1986, namely no fertilization, mineral fertilization, mineral fertilization combined with rice straw or chicke

Purpose: Age-related macular degeneration (AMD) is generally considered a disease of the macula. However, recent studies show peripheral retinal lesions are prevalent in patients with AMD, indicative of a disease process that is more widespread. Full-field electroretinography (ffERG) measures an electrical response, not only from the macula, but from the entire retina. We wanted to study the ffERG

När sultanens sändebud Mehmed Said Efendi äntligen stiger i land i Stockholm sommaren 1733 hälsas han av – enligt egen utsago – ”druvklasar” av åskådare, kanonsalvor och en ståtlig kortege. Resan hade tagit mer än ett halvår och hemma i Istanbul rådde politisk oro efter att den reformvänlige och tulpanälskande sultanen Ahmed III störtats.Historikern Joachim Östlund återskapar atmosfären och miljön

Three-dimensional live imaging has become an indispensable technique in the fields of cell, developmental and neural biology. Precise spatio-temporal manipulation of biological entities is often required for a deeper functional understanding of the underlying biological process. Here we present a home-built integrated framework and optical design that combines three-dimensional light-sheet imaging

Phagocytic immune cells such as microglia can engulf and process pathogens and dying cells with high efficiency while still maintaining their dynamic behavior and morphology. Effective intracellular processing of ingested cells is likely to be crucial for microglial function, but the underlying cellular mechanisms are poorly understood. Using both living fish embryos and mammalian macrophages, we

BACKGROUND: The spinal cord is composed of a large number of cells that interact to allow the organism to function. To perform detail studies of cellular processes involved in spinal cord injury (SCI), one must use repeatable and specific methods to target and injure restricted areas of the spinal cord.NEW METHOD: We propose a robust method to induce SCI in zebrafish by laser light. With a 2-photo

OBJECTIVES: Clinical presentation of primary Sjögren's syndrome (pSS) varies considerably. A shortage of evidence-based objective markers hinders efficient drug development and most clinical trials have failed to reach primary endpoints.METHODS: We performed a multicentre study to identify patient subgroups based on clinical, immunological and genetic features. Targeted DNA sequencing of 1853 auto