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Liver cirrhosis is a risk factor for hepatocellular carcinoma (HCC). While the HCC risk is thought to be highest in hepatitis B and hepatitis C, the risk in other cirrhosis etiologies is not fully established. Therefore, we aimed to study the risk and outcome of HCC in alcoholic cirrhosis compared to cirrhosis of other etiologies, in Sweden. New publication in Scandinavian Journal of Gastroenterol

https://www.lupop.lu.se/article/risk-and-outcome-hepatocellular-carcinoma-liver-cirrhosis-southern-sweden-population-based-study - 2025-11-22

Want research in Europe to be more FAIR? Your views count! FAIRsFAIR Open Consultation is open. Read more here.

https://www.lupop.lu.se/article/fair-data-policies-and-practices - 2025-11-22

The conference theme, “Data by Design: Building a Sustainable Data Culture”, emphasizes two core values embedded in the culture of Gothenburg and Sweden: design and sustainability. Read more here.

https://www.lupop.lu.se/article/46th-annual-iassist-conference-gothenburg - 2025-11-22

Under seminariet presenterades den andra, kvantitativa, delstudien av forskares attityder till forskningskommunikation och öppen vetenskap. Studien bygger på enkätsvar från cirka 3 700 forskare vid svenska lärosäten. Se en inspelning av seminariet här.

https://www.lupop.lu.se/article/dialogseminarium-om-forskare-och-kommunikation - 2025-11-22

Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor–outcome association. However, the relative importance of selection bias for Mendelian randomization compared with other potential biases is unclear. New publication in International Journal of Epidemiology.Read more

https://www.lupop.lu.se/article/contextualizing-selection-bias-mendelian-randomization-how-bad-it-likely-be - 2025-11-22

Cross-sectional normative dual energy X-ray absorptiometry data in 1052 men aged 18–28 years New publication in BMC Musculoskeletal Disorders.Read more here.

https://www.lupop.lu.se/article/does-peak-bone-mass-correlate-peak-bone-strength - 2025-11-22

The European Medicines Agency (EMA) established the Patient Registry Initiative to explore ways of supporting the use of patient registries in generating high-quality data for regulatory decision making and to enable a systematic approach to their use. We review barriers and opportunities for using patient registries in medicines regulation. A key aspect is that early discussions between all parti

https://www.lupop.lu.se/article/barriers-and-opportunities-use-patient-registries-medicines-regulation - 2025-11-22

Soil-transmitted helminth infections have been found to be associated with child development. The objective was to investigate hemoglobin levels and malnutrition as mediators of the association between Ascaris infection and intelligence quotient (IQ) scores in children. New publication in Epidemiology.Read more here.

https://www.lupop.lu.se/article/bayesian-methods-exposure-misclassification-adjustment-mediation-analysis - 2025-11-22

Establishment of orthopaedic registers started in 1975 and many registers have been initiated since. The main purpose of registers is to collect information on patients, implants and procedures in order to monitor and improve the outcome of the specific procedure. New publicatoin in Efort.Read more here

https://www.lupop.lu.se/article/what-when-and-how-orthopaedic-registers-introduction-register-based-research-0 - 2025-11-22

This is an open seminar with professor Miguel Hernán A 3 half-day seminar on Causal Inference with Miguel Hernán, professor of Biostatistics and Epidemiology at Harvard School of Public Health.The scheduel is as follow:Monday May 6 at 1-5PMTuesday May 7 at 1-5PMWednesday May 8 at 9-12AMLocation: Arvid Carlsson, Acadmicum, GothenburgRead more here 

https://www.lupop.lu.se/article/learning-what-works-framwork-causal-inference-observational-data - 2025-11-22

Most respondents used quality indicators from the two cardiovascular NQRs infrequently (<3 times/year). The results indicate that linking registration of quality indicators to using them for QI activities increases their routine use and makes them meaningful tools for professionals. New publication in International Journal for Quality in Health CareRead more here

https://www.lupop.lu.se/article/quality-indicators-and-their-regular-use-clinical-practice-results-survey-among-users-two - 2025-11-22

The questionnaire measures and detects differences in patient well-being, abilities and judgements of diabetes care, and identifies areas for improvement. To further improve diabetes care, we conclude that patient-reported measures are important supplements to cardiovascular and diabetes complication risk factors, reflecting patient experiences of living with diabetes and diabetes care. New public

https://www.lupop.lu.se/article/patient-reported-outcome-and-experience-measures-diabetes-development-scale-models-differences - 2025-11-22

There has been marked growth in reports addressing exposure-affected time-varying confounding. This was driven by work in a small number of topic areas, with other areas showing relatively little uptake. In addition, despite developments in more advanced methods such doubly robust techniques and estimation via machine learning, implementation has been largely concentrated on the simpler, yet poten

https://www.lupop.lu.se/article/causal-models-adjusting-time-varying-confounding-systematic-review-literature - 2025-11-22

Valentin Amrhein, Sander Greenland, Blake McShane and more than 800 signatories call for an end to hyped claims and the dismissal of possibly crucial effects. Read more here.

https://www.lupop.lu.se/article/scientists-rise-against-statistical-significance - 2025-11-22

Impressions from SND workshop on data management plans Click here to read the newsletter!

https://www.lupop.lu.se/article/new-issue-lu-snddosp-newsletter - 2025-11-22

The Board of EAO (European Association for Osseointegration) has discussed an initiative to explore the conditions to establish a Dental Implant Register. It was suggested to bring this issue to the EAO Consensus Conference 2018 for a discussion and to possibly propose relevant and manageable parameters. This article presents some select examples from quality registers in the medical field. New pu

https://www.lupop.lu.se/article/dental-implant-quality-register-possible-tool-further-improve-implant-treatment-and-outcome - 2025-11-22

Internet-based reporting for patient-reported outcomes in a clinical setting resulted in similar data for VASs and corresponding disease activity scores to clinic-based reporting on paper forms. New publication in Scandinavian Journal of RheumatologyRead more here

https://www.lupop.lu.se/article/comparison-agreement-between-internet-based-registration-patient-reported-outcomes-and-clinic-based - 2025-11-22

Over the last decades the advent of digital documentation has provided research communities with valuable resources of information for clinical research. To utilize the potential of information about patients, their health care, and its outcome that is already available in different registers, the possibility to cross-reference information from different registers is inevitably required. New publi

https://www.lupop.lu.se/article/de-identified-linkage-data-across-separate-registers-proposal-improved-protection-personal - 2025-11-22

Surgery for oesophageal and gastric cancers is associated with high morbidity, mortality and poor quality of life postoperatively. The Finnish National Esophago-Gastric Cancer Cohort has been established with the aim of identifying factors that could contribute to improved outcomes in oesophago-gastric cancer. New publication in BMJ Open.Read more here

https://www.lupop.lu.se/article/finnish-national-esophago-gastric-cancer-cohort-finego-studying-outcomes-after-oesophageal-and - 2025-11-22

En fallstudie av några forskningsorienterade institutioner Läs mer här

https://www.lupop.lu.se/article/externfinansieringens-roll-i-svensk-hogskoleforskning - 2025-11-22