Integrins are adhesion molecules that control cell to cell interactions and play a fundamental role in adhesion of T cells during an immune response. Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) is an important regulatory factor of the integrin lymphocyte function-associated antigen 1 (LFA1). A single-nucleotide polymorphism in the gene coding for PTPN22 has previously been linked as

Tilting är en vanlig term inom världen av tävlingsinriktade tvspel, dock har det inte forskats mycket om ämnet. Syftet med den här studien är att klargöra om folk känner att deras prestation i ett tävlingsinriktat multiplayerspel negativt påverkas av ilska, och vice versa. En onlineenkät publicerades på forum dedikerade till specifika tävlingsinriktade spel, där deltagarna fick svara på frågor om Tilting is a common term in competitive video gaming, although not much research has been conducted on the subject. The aim of this study is to ascertain whether people feel that their performance in a competitive video game is negatively affected by anger, and vice versa. An online survey was published on forums dedicated to certain competitive video games, within which the subjects answered ques

Facklig anslutning har avtagit kontinuerligt i Sverige sedan tidigt 90-tal. Kommunikativ krisberedskap torde därmed vara högt på agendan för svenska fackförbund. Ändå förefaller det inte vara fallet. Syftet med denna studie är således att bidra till ökad kunskap inom fälten strategisk kommunikation- och strategisk kriskommunikation inom facklig verksamhet. Studien ämnar undersöka hur det svenska f

Uppsatsens övergripande syfte är att genom förvaltningsrättsliga domar som avser 2 § lag (1990:52) med särskilda bestämmelser om vård av unga förstå hur föräldraskapet konstrueras och framställs i tvångsvårdsdiskursen med hänsyn till normativa föreställningar. Syftet är även att belysa hur maktrelationen ser ut mellan rätten, sociala myndigheter och föräldrarna i domsluten.

Denna uppsats grundar sig på en översättning av en medicinsk, psykiatrisk artikel Ob otnosjenie lichoradotjnych bolneznyj k psichozam ('Om febersjukdomarnas förhållande till psykoser'), författad av läkaren och psykiatern Alexander Samojlovitj Rozenbljum i Odessa och publicerad 1876 i den medicinska tidskriften Trudy vratjej Odesskoj gorodskoj bolnitsy ('Skriftserie utgiven av läkarna

During manufacturing of beverage packages, the pre-laminated hole get subjected to various mechanical loading. Thus needs a greater comprehension and knowledge of its behaviour to understand packaging materials. In this Master's thesis, the behaviour of the thin membranes consisting of polymer and aluminium foil has been studied when subjected to pressure. Mechanical, visual, as well as virtua

About 25,3 % of the Mozambican population is suffering from undernourishment even though a sufficient amount of food and specifically fruits are produced. Post-harvest losses are estimated to 25 % to 40 % and part of the production is not even harvested due to a short season. A solution has to be found to improve fruit preservation and allow the population to consume what is harvested later. Dryin

Capitalizing reforms would come to China in 1978, and to the U.S.S.R. in 1985. While the Chinese reforms have been uninterrupted to the modern day, similar reforms in the Soviet Union would lead to its collapse, and to the adoption of capitalism by the Russian Federation. These 'communist' economic reforms were political movements informed by ideology, but China’s more effective reforms re

Sverige brukar få hög placering i internationella jämförelser av sjukvårdssystem. Det gäller inte minst patientnöjdhet och kvalitet, läkartäthet och hälsoutfall. Ändå har de senaste åren varit mycket vanligt med larmrapporter om kris på sjukhusen med påstådda överfulla vårdsalar och personal som lämnar sjukvården pga för hög arbetsbörda och ohållbar arbetsmiljö. Situationen har dragit igång debattData Envelopment Analysis (DEA) which compares different Decision Making Units (DMUs) has been used by some scholars to find the most efficient hospitals within Sweden or within Nordic countries. In Sweden, healthcare is decentralized and provided mostly by the 21 county councils. Even private providers have to sign contracts with the county councils in order to be permitted to operate within thei

Optical DNA mapping offers an alternative or complementary method of sequencing and identification to the widely used next generation sequencing techniques. However, the rich selection of computational tools found for standard nucleotide sequencing are not as mature for DNA optical maps. This thesis focuses on two tools for the analysis of densely labeled optical maps. Firstly, parameters for an e

The corporate bankruptcy is a significant problem for economy since it is considered as a limiting factor for economic growth. The financial crisis that broke out in USA on 2007 as a result of miscalculated subprime mortgage strategies turn into a full international banking crisis affecting successively the European banks, especially those of South European countries. Given that the role and the i

Reglering och transport av S100A9 i cancer S100A9 är ett protein involverat i immunförsvaret och fungerar som en signal mellan olika celler för att optimera inflammation. Bortsett från det, har immunförsvaret som roll att bekämpa cancer. Där blir i stället effekten av S100A9-signalering att immunförsvarets attack dämpas och tumören gynnas. Det är därför av intresse att veta mer om detta signalsysS100A9 is a calcium binding protein commonly found in cancer, autoimmunity and inflammation. Factors in the tumor microenvironment can induce cancer cells to start expressing S100A9. This protein has also been found to be up regulated and have different subcellular distribution during hypoxia. In this study I used western blot to analyze the regulation of expression and intra-cellular transport of

Mammalian cells are frequently under stress leading to DNA damage because of UV exposure, ionizing radiation or genotoxic chemicals. Cells have evolved a DNA damage response (DDR) mechanism to ensure survival and pass on the correct genetic information to the next generation. MITF is a melanocyte-specific transcription factor. It has been shown to accumulate in the vicinity of DNA damage and its e

A mysterious gene found in many bacteria Recently, a gene called ctaM was discovered in Staphylococcus aureus, a common cause of skin infections etc., required for the bacterium to respire efficiently. It was demonstrated that the protein encoded by this gene is essential for the function of cytochrome aa3, that catalyzes the reduction of O2 to form H2O in respiration. A gene encoding a similar p

The single-stranded telomere ends The telomeres are tandem repeat DNA sequences at the ends of our chromosomes. They are very important for the protection of our genomic DNA, and keeps it from being degraded and helps it staying intact. Genomic DNA is usually double-stranded, but on the very ends of the telomeres we find single-stranded ends which are called the 3’overhangs. These overhangs are

This study investigates the effect of unemployment on health and rank-dependent indices of income-related health inequality in Europe during the period 2006-2015, using data from the Survey of Health, Ageing and Retirement in Europe. I use a recently proposed general method of decomposition and a panel data approach with individual fixed effects, and find a significant negative relationship betwee

Entrepreneurial motivations are still a relatively undiscovered research field (Carsrud & Brännback, 2010). More specifically there seems to be a gap in the literature about the motivation of older entrepreneurs (Weber & Schaper, 2004). Weber and Schaper (2004) mentioned that this segment will have a growing impact upon national economic performance, policy frameworks, academia and the bus

Igenkänning och signalering av växthormonet brassinosteroid i korn Under svåra väderförhållanden som starka vindar, hagel eller hårt regn kan grödor som korn pressas mot marken – man får liggsäd. Dessa löper större risk att drabbas av svampinfektioner, de börjar gro och de blir svårare att tröska vilket minskar skörden. Sädesslag som korn, vete och råg är extra utsatta, vilket skapar ett behov av

This study aims to explore how the Swedish Migration Court’s decision is legitimized or delegitimized in discourses in civil society, outside the legislative and judicial power. This is explored with a case study on a judicial decision to expel Sonya, a 90-year-old and sick Ukrainian woman. The material is collected from social media platforms where this case has been discussed. Thus, the results

The study focuses on the impact of United Kingdom’s vote for leaving the European Union on the banks stocks in Europe. The tool used for measuring this impact is event study. Putting the center of attention on the banking industry, we investigate 63 major banks in Europe. Abnormal returns are defined by using the well-known market model. As expected, the results show that banks experience signific