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Successful bacterial pathogens produce an array of virulence factors that allow subversion of the immune system and persistence within the host. For example, uropathogenic Escherichia coli strains, such as CFT073, express Toll/IL-1 receptor-containing (TIR-containing) protein C (TcpC), which impairs TLR signaling, thereby suppressing innate immunity in the urinary tract and enhancing persistence i
One promising method to prepare protein-selective polymers is the epitope-imprinting approach, where surface-accessible peptides from a target protein are used as templates to create surface-exposed binding sites on molecularly imprinted polymers (MIPs). However, selection of a suitable peptide target is not always straightforward, and synthesis of peptide on a large scale can be costly. In this w
PurposeThe purpose of this paper is to develop new conceptual tools for analyzing how contemporary collaborative academic work is organized on micro-level, and its social and economic impact, in broad terms. Thus it makes a contribution towards a better view on how contemporary academics organize their professional activities in light of profound changes to the framework conditions of academic wor
This study revives a heavily debated relationship between government debt accumulation and economic growth. Although indebtedness levels stay high, current economic growth forecasts seem optimistic not only in the euro area but in other advanced countries, as well. 24 advanced OECD economies are investigated to understand if financial outcomes are detrimental to the real economic variables in the
Against the grain of the paradigmatic postcolonial analytics of the colonial state, this chapter presents a non-dichotomous comparison of two regimes within the late 18th century Danish empire, which are commonly presumed to be of essentially different kinds - namely the colonial state in Tranquebar in South East India and the metropolitan government of rural Danish society. By focusing, firstly,
BACKGROUND: Phosphoglucose isomerase (PGI, EC 5.3.1.9) is an essential metabolic enzyme in all eukaryotes. An earlier study of the PgiC1 gene, which encodes cytosolic PGI in the grass Festuca ovina L., revealed a marked difference in the levels of nucleotide polymorphism between the 5' and 3' portions of the gene.METHODS: In the present study, we characterized the sequence polymorphism in F. ovina
Large infrastructure projects often involve important decision about evacuation safety measures, e.g., emergency exit portals, alarm systems, etc, that need to be taken in spite of limited information and knowledge about the topic. This has been shown to sometimes lead to design mistakes, but these mistakes can potentially be avoided if research is linked to the project at an early stage. This pap
We examine economic inequality and social differences in infant and child mortality, and fertility responses to food price changes in North Orkney, 1855–1910, using linked vital records. This small population featured a diverse occupational structure, limited land resources, and geographic isolation from mainland Scotland. Segments of Orkney’s non-agricultural working population were living so clo
In recent years, there has been a revival of interest in a time-honored tool of the clotting trade: the thrombin generation curve or thrombin generation (TG) assay (TGA) as we now call it. Thrombin generation is a key coagulation process that determines the extent of a hemostatic plug or a thrombotic process. The recent development of newer tests based on the continuous registration of TG under in
Mother-tongue education can be seen as an important tool for minority children to gain or maintain proficiency in their mother-tongue. They will thereby uphold a cultural and social link to the country and culture of origin. Advocates of mother-tongue education in school also highlight the importance of knowing one’s mother-tongue for successful second language acquisition. Others argue that the f
The dependency of the atmospheric boundary layer (ABL) characteristics on the ABL's height is investigated by using large eddy simulations (LES). The impacts of ABL's height on the wind turbine (WT) power production are also investigated by simulating two subsequent wind turbines using the actuator line method (ALM). The results show that, for the same driving pressure forces and aerodynamic rough
Hematopoiesis is defined as the ongoing production of blood cells. As most mature blood cells are relatively short-lived and require continuous replacement, hematopoiesis is characterized by an extraordinary turnover rate with production of trillions of new blood cells every day. To cope with the enormous proliferation required to generate sufficient numbers of blood cells to maintain homeostasis,
This paper presents two case studies of Swedish ICT 'gap exploiter' companies to provide a nuanced perspective in the investigation of ICT reuse business models and policies. Gap exploiters are third-party firms that create value through the re-utilization of existing products. While extending product life through the gap exploiter model is promising in the transition to a circular economy, busine
Carbon dioxide expanded liquids (CXLs) is a relatively recent type of solvent used in separation processes such as extraction. It combines the benefits of high solubility in the organic liquid with enhanced mass transfer mediated by the compressed CO2. In this work, we investigate the solubility of curcumin in CO2-expanded ethanol and for this purpose an equipment setup was built and used for expe
Monitoring of forest carbon fluxes for the purpose of national greenhouse-gas inventorying and reporting are commonly based on repeated large-scale field measurements. Alternate approaches based on modelling of forest growth offers potential benefits such as cost savings and detailed assessments of involved carbon fluxes. We calculated the net primary productivity (NPP) of Swedish forests using tw
Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases. To date, it has been possible to obtain GABAergic and glutamatergic neurons via in vivo conversion, but the precise phenotype of these cells has not yet been analyzed in detail. H
