In recent times, the philosophy of science has been reinvigorated by insights from the biological and cognitive sciences. These disciplines have provided not only new perspectives to approach traditional philosophical problems but have also opened the way to new conceptual and methodological questions that call for new and innovative solutions.This book brings together some of the main debates tha

Venous thromboembolism (VTE) involves blood clot formation in veins, resulting in serious health issues. Fibrinogen, a crucial clotting protein, consists of three polypeptides encoded by the fibrinogen genes: alpha (FGA), beta (FGB) and gamma (FGG). We genotyped most common missense variants in the fibrinogen genes in relation to VTE, recurrence and family history in Malmö Thrombophilia Study, inc

In a questionnaire, participants judged the increase in SARS-CoV-2 virus exposure when moving closer to an infected person. Earlier studies have shown that the actual increase in virus exposure is underestimated and the present study replicated and extended these studies. The primary purpose was to investigate to what extent questionnaire judgments about hypothetical situations can predict judgmen

Evolutionary biologists today debate whether it is convenient to revise the standard theory of evolution, or if an Extended Evolutionary Synthesis is necessary. However, the conceptual relationship between the standard theory of evolution (also known as the Modern Synthesis) and a putative Extended Evolutionary Synthesis is not clear. One concept in philosophy of science that has traditionally bee

Based on field measurements in 26 Ethiopian homes, we have estimated an average indoor air exchange rate (AER). In laboratory settings, using on-line methods, we have burned common solid biofuels (charcoal, wood, cow dung, crops residue) in a traditional way, thereby generated airborne particles, and assessed various aerosol characteristics. All the fuels generated PM2.5 (particles smaller than 2.

To extend the output DC power range of energy harvester from μW to mW, the 29.5 GHz rectifier using vertical nanowire Tunnel Field-Effect Transistor (VNW-TFET) is presented in this paper. Advantaged by the low threshold voltage, very steep characteristics, and its ability to operate below 60mV/decade, VNW-TFET is a promising device in rectifier design for low power applications. By analyzing the r

In recent times, the philosophy of science has been reinvigorated by insights from different biological and cognitive sciences. These disciplines have provided not only new approaches to traditional philosophical problems but have also opened the door to new conceptual puzzles. The fundamental aim of this volume is to bring together some of the main debates that have structured the fields of philo

Background: The water supply in the Gaza Strip, Palestine, has been unstable and under strain for decades, resulting in major issues with drinking water quality, reliability, and acceptability. In 2018, between 25% and 30% of Gazans did not have regular access to running water. The progressive deterioration of water infrastructure and concerns over the quality of piped water have resulted in a com

In recent years, stochastic partial differential equations (SPDEs) have become a well-studied field in mathematics. With their increase in popularity, it becomes important to efficiently approximate their solutions. Thus, our goal is a contribution towards the development of efficient and practical time-stepping methods for SPDEs. Operator splitting schemes provide powerful, efficient, and flexibl

Reactive oxygen species (ROS) are considered to be an indicator of particle-induced toxicity. We used a novel instrument, called Particle Into Nitroxide Quencher (PINQ), for real-time quantification of ROS for assessment of indoor particle sources. Of the sources tested, cigarette smoke was found to contain the highest ROS concentration, several times higher than incense smoke and secondary organi

Rodent models are important research tools for studying the pathophysiology of traumatic brain injury (TBI) and developing new therapeutic interventions for this devastating neurological disorder. However, the failure rate for the translation of drugs from animal testing to human treatments for TBI is 100%. While there are several potential explanations for this, previous clinical trials have reli

The building and construction sector is responsible for a significant portion of embodied and energy related carbon emissions. Efforts to reduce this are reflected in the need for improved sustainability in the design, construction, and operation of structures such as buildings and bridges. This issue has become more prominent in recent decades due to the ongoing climate crisis. A historical revie

Objective: This study examined the prevalence and long-term survival of atrial fibrillation (AF) in the older population. Methods: Data was recruited from the longitudinal SNAC study from baseline (2001–2004) for up to 10 years. Results: The population comprised 6,904 persons (59% women) (mean age 73.9 years). The prevalence of AF was 4.9% and increased with age. The hazard ratio (HR) for death in

This paper presents a method for evaluating the potential for injury in any traffic scenario involving road user interactions based on trajectory data from a few hours of data of typical traffic conditions. The basic idea was to evaluate to what extent interactions at a location are limited in speed, direction, and whether the interactions happen at a safe speed. Specifically, the method works by

Recently approved anti-amyloid immunotherapies for Alzheimer's disease (AD) require evidence of amyloid-β pathology from positron emission tomography (PET) or cerebrospinal fluid (CSF) before initiating treatment. Blood-based biomarkers promise to reduce the need for PET or CSF testing; however, their interpretation at the individual level and the circumstances requiring confirmatory testing are p

This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional characterization of mouse and human dendritic cells (DC) from lymphoid organs, and various nonlymphoid tissues. Within this article, detailed protocols are prese