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During the last decade, software process simulation has been used to address a variety of management issues and questions. These include: understanding; training and learning; planning; control and operational management; strategic management; process improvement and technology adoption. This paper presents a simulation model that was developed to demonstrate the impact of unstable software requir

An improved clocking scheme and sharper circuit design and logic selection, which have yielded a five-to-tenfold increased in the speed of standard CMOS ICs, are discussed. The clocking strategy relies on a true single-phase clock, device sizes are varied to optimize their speed, and a precharged logic style reduces capacitive loads. The tradeoff is roughly a doubling of circuit area. The high-spe

In both chronic obstructive pulmonary disease (COPD) and multiple sclerosis (MS), combinations of environmental and genetic factors are likely to increase the vulnerability to acquire disease. This study was undertaken to investigate any possible comorbidity of COPD and MS, thus indicating common inflammatory vulnerability. Individuals with a diagnosis of COPD (including chronic bronchitis and emp

Aims and objectives. To explore the development over time of beliefs about health, illness and health care in migrant women with gestational diabetes mellitus born in the Middle East and living in Sweden and to study the influence on self-care and care seeking. Background. With today's extensive global migration, contact with the new society/health care confronts the migrant's culture of origin wi

Krönika om den ideologiska förändringen av filmserien om James Bond.

BACKGROUND: The same mechanisms by which ultrasound enhances thrombolysis are described in connection with non-beneficial effects of ultrasound. The present safety study was therefore designed to explore effects of beneficial ultrasound characteristics on the infarcted and non-infarcted myocardium. METHODS: In an open chest porcine model (n = 17), myocardial infarction was induced by ligating a co

In December 2005, the WTO responded to the HIV/AIDS pharmaceutical crisis in the least developed world by voting to make the first permanent amendment to the WTO Agreements since their original negotiation during the Uruguay Round. New Article 31bis will amend the TRIPS Agreement to permit compulsory manufacturing licenses in order to facilitate supply of needed pharmaceuticals to those countries

Hippuric acid has been a major human metabolite for years. However, there is no well-known documented health benefit associated with it except for excretion of environmental-toxic exposures of aromatic compounds such as toluene, or from dietary protein degradation and re-synthesis by intestinal microflora metabolism of quinic acid via the shikimate pathway. Thus hippuric acid can appear in humans

Objective. To illustrate the impact on settling neonatal metabolic acidosis diagnosis by rounding off pH and base deficit (BD) case value decimals. Design. Comparative study. Setting. University maternity units. Sample. Umbilical cord arterial blood gas values from 18 831 newborns. Main outcome measures. Prevalences of pH <7.05 and metabolic acidosis diagnosis (pH <7.05 plus BD >12.0 mmol/L). Meth

Cytomegalovirus induces a chronic infection that in normal individuals is controlled by the immune system. In the case of humoral immunity, epitopes, in particular antigenic domain-1, in glycoprotein B have proven to be important for the induction of virus-neutralizing activity. Such antibodies can exert potent virus-neutralizing activity but can also block neutralizing antibodies from binding. Fu