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Transcription factor 7-like 2 (TCF7L2)

In 2006 a genetic signal within the gene encoding transcription factor 7-like 2 (TCF7L2) was first reported to be associated with type 2 diabetes. Since then multiple genome-wide association studies have revealed this signal to be among the most strongest associations reported with this disease to date. Furthermore, multiple studies around the world have revealed the global relevance of this locus

Comparison and interactions between the long-term pursuit of energy independence and climate policies

Ensuring energy security and mitigating climate change are key energy policy priorities. The recent Intergovernmental Panel on Climate Change Working Group III report emphasized that climate policies can deliver energy security as a co-benefit, in large part through reducing energy imports. Here, using five state-of-the-art global energy-economy models and eight long-term scenarios, we show that w

Cholinesterase inhibitor therapy does not affect time spent in nursing homes in patients with Alzheimer’s disease.

Background: The time spent in nursing homes (NHs) by patients with Alzheimer’s disease (AD) might be influenced by many factors, e.g., sociodemographic and clinical characteristics, rate of disease progression, and concomitant disorders. Whether different aspects of cholinesterase inhibitor (ChEI) therapy (drug agent, dose, and duration) affect time spent in NHs has not been investigated. We studi

Struggling with New Media and Old Expertise: Reconstructing the Professional Role of Communication Consultancy

This study investigates how communication consultants struggle to reconstruct their professional role in the digital media landscape. The extant literature on professional roles in public relations has a tendency to render roles as static pregivens. Therefore, the purpose of this study is to contribute conceptually and empirically to role research by focusing on the process of “role-making” and ho

Recipient and Donor Characteristics - Impact on Outcome after Heart Transplantation

Heart transplantation (HTx) is severely limited by a shortage of donors. This thesis aimed to investigate the effectof variables used to match donors to recipients in HTx.Methods: Data from the ISHLT registry was used to study: I: Identical versus compatible non-identical ABOmatchingin 3,589 AB HTx recipients. II: Outcomes of 94 ABO-incompatible transplants were compared to anABO-compatible group.

Cardiac signal estimation based on the arterial and venous pressure signals of a hemodialysis machine

Continuous cardiac monitoring is usually not performed during hemodialysis treatment, although a majority of patients with kidney failure suffer from cardiovascular disease. In the present paper, a method is proposed for estimating a cardiac pressure signal by combining the arterial and the venous pressure sensor signals of the hemodialysis machine. The estimation is complicated by the periodic pr

Reflective and collaborative skills enhances Ambulance nurses’ competence – A study based on qualitative analysis of professional experiences

Background: The Swedish ambulance health care services are changing and developing, with the ambulance nurse playing a central role in the development of practice. The competence required by ambulance nurses in the profession remains undefined and provides a challenge. The need for a clear and updateddescription of ambulance nurses’ competence, including the perspective of professional experiences

Analysis of pre-hospital rescue times on mortality in trauma patients in a Scandinavian urban setting

Objective: To analyze if pre-hospital rescue times were associated with mortality in a trauma cohort arriving by ambulance to hospital in a Scandinavian urban setting. Methods: Between 2011 and 2013, individuals and pre-hospital rescue times were identified in Emergency Medical Dispatcher Centre, hospital, and forensic records in red alarm trauma. Major trauma was defined as a New InjurySeverity S

Behavioral Spillovers across Prosocial Alternatives

This thesis contributes to the economic literature on prosocial behavior. It includes three papers, all of which relate to the issue of policy-driven spillovers across prosocial alternatives. For example, the common fundraising practice of donation matching could affect contributions through other channels; similarly, recycling policy could affect household efforts on other environmental activitie

On the Performance of Vehicular Communications with a Measurement-Based Radio Propagation Model

The choice of channel propagation model used for the simulation-based study of Vehicular Ad hoc NETworks (VANETs) plays a key role in the accuracy of conclusions drawn about the performance of applications proposed for these networks. Relying on simplistic channel models, as frequently practised in previous works, leads either to pessimistic or optimistic conclusions. In the view of this, in this

Encouraged Intrusion and the Entering of a Subordinate Consumption Field

In order to explore consumer culture’s potential to change social relations, this investigation immerses into the growing consumer culture of foodies occupying the historically feminine space of domestic cooking. It offers a tentative theory on the entering of subordinate consumption fields in contexts where the entering is sanctioned by cultural authorities.

International Retailing as Embedded Business Models

As retailers internationalize they interact with diverse socio-political-economic environ- ments and the activities, processes, behaviours and outputs underpinning their business models evolve over time and space. Retailers are not passive, and through managerial agency they interpret the environment to compete and further their own commercial aims. Consequently, mutual interaction with the host e