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Objectives: Pleural mesothelioma (PM) is a rare disease with dismal outcome. Systemic treatment options include chemotherapy and immunotherapy, but biomarkers for treatment personalization are missing. The only FDA-approved diagnostic biomarker is the soluble mesothelin-related protein (SMRP). Krebs von den Lungen-6 (KL-6) is a human mucin 1 (MUC1) glycoprotein, which has shown diagnostic and prog

Four new superdeformed bands have been found in the nucleus [Formula Presented]. The good agreement between experiment and configuration-dependent shell correction calculations suggests that three of the bands have triaxial superdeformed shapes. Such unique features in mass [Formula Presented] superdeformed bands have been predicted, but not observed experimentally until now. A fourth band in [For

The configuration-dependent shell-correction approach with the cranked Nilsson potential is employed for a systematic investigation of the high-spin spectra of the nuclei in the A ∼ 135 (Z = 57-61, N = 72-78) mass region, where superdeformed bands have been observed. Main attention is paid to the coexistence of intruder νi13/2, superdeformed and terminating bands in the yrast region. Recent develo

Using new high-resolution data of CO (2-1), H and H obtained with the Northern Extended Millimeter Array (NOEMA) and the Multi-Unit Spectroscopic Explorer (MUSE) at the Very Large Telescope, we have performed a Toomre Q disc stability analysis and studied star formation, gas depletion times and other environmental parameters on sub-kpc scales within the z ∼0 galaxy SDSS J125013.84+073444.5 (LARS 8

A decoupled rotational band with an average dynamical moment of inertia [Formula Presented] [Formula Presented]/MeV has been observed to high spin in [Formula Presented] [Formula Presented]. The measured quadrupole moment of [Formula Presented] eb is as large as that of the superdeformed band in [Formula Presented]. The large deformation and decoupled character of the band suggests that the odd ne

The switch process alternates independently between 1 and −1 , with the first switch to 1 occurring at the origin. The expected value function of this process is defined uniquely by the distribution of switching times. The relation between the two is implicitly described through the Laplace transform, which is difficult to use for determining if a given function is the expected value function of s

We report on a computational study of resonant inelastic x-ray scattering (RIXS), at different fluorine K-edge resonances of the SF6 molecule, and corresponding nonresonant x-ray emission. Previously measured polarization dependence in RIXS is reproduced and traced back to the local σ and π symmetry of the molecular orbitals and corresponding states involved in the RIXS process. Also electron-hole

Radioembolization with 166Ho microspheres is a minimally invasive procedure in which radioactive microspheres are administered directly to liver tumor via the hepatic artery during an interventional radiological procedure. Scout and therapeutic doses of 166Ho were delivered to patients in 2022 and 2023 at VilniusUniversity Hospital Santaros Klinikos. The presented study was aimed at investigating

There are different ways of dividing psychology into subdisciplines. The purpose of the present paper is to explore one specific metaperspective on psychological science, seen as having three main branches: person psychology, population psychology, and mechanism psychology, linked to three different levels of research. Person-level research focuses on psychological phenomena as experienced and ena

Den här översikten följer den svenska flickboken fram till cirka 1930. Denna existerade inte i ett vakuum; översättningar fortsatte att strömma in, och det känns naturligt att behålla ett internationellt perspektiv. Det är dock flickboken i Sverige som står i centrum, sådan den svenska läsarinnan mötte den, varför utländska verk här kommer att anges med sin översatta titel och det år det utgavs –

Prior to the operation of the first Belarussian nuclear power plant (BelNPP), the baseline of the radiation environment was determined within a radius of about 30 km from BelNPP. This independent assessment was carried out during two expeditions in 2019. In 2022, a similar survey was carried out (during the initialoperation of BelNPP) on the Lithuanian side of the boarder. Here we present the over

Numerous factors shape the evolution of protein-coding genes, including shifts in the strength or type of selection followinggene duplications or changes in the environment. Diatoms and other silicifying organisms use a family of silicon transporters(SITs) to import dissolved silicon from the environment. Freshwaters contain higher silicon levels than oceans, and marinediatoms have more efficient

Diets rich in saturated fat and sedentary lifestyles markedly contribute to obesity and metabolic syndrome-related diseases, including type 2 diabetes mellitus (T2D). Metabolite profiling plays a pivotal role in understanding these metabolic diseases. This thesis comprises insights from four distinct studies to illuminate metabolic imbalances induced by diet-induced obesity (DIO), covering topics

Social trust is a moral resource with a normatively highly desirable pay-off. Previous research argues that universal welfare state programmes ‘make’ social trust whereas means-testing programmes ‘break’ it. Despite its important implications for welfare-state design, comparative longitudinal evidence for this hypothesis is scarce. To test whether within-country changes in social trust are associa

Cardiometabolic diseases are the leading preventable causes of death in most geographies. The causes, clinical presentations, and pathogenesis of cardiometabolic diseases vary greatly worldwide, as do the resources and strategies needed to prevent and treat them. Therefore, there is no single solution and health care should be optimised, if not to the individual (ie, personalised health care), the