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In this issue, Weiss discusses “generalizing” inferences from randomized trials to other populations. However, he does not explicitly define what “generalizing” means, assumes that “generalizing” the results of a randomized trial has a single goal, and reduces generalizability to a binary subjective judgment—findings are either generalizable or not generalizable. New publication in European Journa

https://www.lupop.lu.se/article/extending-inferences-randomized-trial-target-population - 2025-11-06

The influence of gender on bipolar disorder is controversial and it is unclear if inpatient care differs between men and women. Here, we investigate for gender differences in the inpatient length of stay for Swedes admitted for bipolar disorder and explore other factors that could explain any observed association. New publication in Journal of Affective Disorders

https://www.lupop.lu.se/article/gender-influence-bipolar-disorder-inpatient-length-stay-sweden-2005-2014-register-based-study - 2025-11-06

When analyzing effect heterogeneity, the researcher commonly opts for stratification or a regression model with interactions. While these methods provide valuable insights, their usefulness can be somewhat limited, since they typically fail to take into account heterogeneity with respect to many dimensions simultaneously, or give rise to models with complex appearances. New publication in European

https://www.lupop.lu.se/article/assessing-heterogeneous-effects-and-their-determinants-estimation-potential-outcomes - 2025-11-06

Data on the 4466 trauma patients in the registry were analysed. Out of 59 variables, most (n = 51; 86.4%) were missing less than 20% of observations. There were 808 (18.1%) patients missing at least one of the first in-hospital physiological observations. Hospital death was associated with missing in-hospital physiological data (adjusted OR 1.4; 95% CI 1.02–2.01; p = 0.04). New publication in Worl

https://www.lupop.lu.se/article/establishing-multicentre-trauma-registry-india-evaluation-data-completeness - 2025-11-06

According to rough estimates, there are approximately 150,000 rare disease patients in Slovenia (out of a total population of 2 million). Despite the absence of accurate epidemiological data on their status, these figures reveal the great importance of this area for the Slovenian healthcare system. New publication in Orphanet Journal of Rare Diseases

https://www.lupop.lu.se/article/development-pilot-rare-disease-registry-focus-group-study-initial-steps-towards-establishment-rare - 2025-11-06

The study aim was to report survival and morbidity of all patients in Sweden with peritoneal mesothelioma treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) as well as investigate whether the survival has increased on a population level since this treatment was nationalized 2011. Study data were collected from the Swedish HIPEC registry and the Swedish N

https://www.lupop.lu.se/article/peritoneal-mesothelioma-sweden-population-based-study - 2025-11-06

Regulators increasingly rely on registries for decision making related to high‐risk medical devices in the United States. However, the limited uniform standards for registries may create substantial variability in registry implementation and utility to regulators. We surveyed the current landscape of US cardiovascular device registries and chart the extent of inconsistency in goals, administration

https://www.lupop.lu.se/article/landscape-cardiovascular-device-registries-united-states - 2025-11-06

Survey response rate was 98% (54/55). Overall, 57% perceived that using registry data saved research staff time in the current study, and 74% perceived that it would save time in future studies; 55% noted significant upfront time in developing a methodology for extracting registry data. Survey recommendations included simplifying data extraction processes and tailoring to the needs of the study, u

https://www.lupop.lu.se/article/lessons-learned-use-clinical-registry-data-multi-centre-prospective-study-pediatric-heart-network - 2025-11-06

Using a continuous exposure variable that is measured with random error in a univariable linear regression model leads to regression dilution bias: the observed association between the exposure and outcome is smaller than it would be if the true value of the exposure could be used. A repeatability sub-study, where a sample of study participants have their data measured again, can be used to correc

https://www.lupop.lu.se/article/reflection-modern-methods-calculating-sample-size-repeatability-sub-study-correct-measurement-error - 2025-11-06

Recently, King et al.1 assessed the effect of disability on mental health through bullying in adolescents using a causal mediation analysis method developed by Valeri and VanderWeele2 in which exposure–mediator interactions are allowed. In the latter method, one can only handle time-fixed exposure and mediator, and, for this reason, the authors only used the exposure in wave 5 and mediator (and ou

https://www.lupop.lu.se/article/methodological-point-mediation-analysis - 2025-11-06

In healthcare, we have kept notes on people with diseases for over 4000 years. These have been a combination of subjective commentary and objective measurement. In the past 30 years recording data on patients has been systematised through disease registries and electronic patient records (EPR). We now have extensive registries in many diseases with robust cross-sectional and more importantly, long

https://www.lupop.lu.se/article/using-registries-research-cf-how-can-we-be-sure-about-outputs - 2025-11-06

The purpose of this paper is to understand what role researchers assign to online representations on the new digital communication sites that have emerged, such as Academia, ResearchGate or Mendeley. New publication in emerald insight

https://www.lupop.lu.se/article/researchers-online-visibility-tensions-visibility-trust-and-reputation - 2025-11-06

With the most important stories from Nordic section of European Open Science Cloud (EOSC). Read more here.

https://www.lupop.lu.se/article/first-issue-eosc-nordic-newsletter - 2025-11-06

Bibsamkonsortiet tecknar ett läs- och publiceringsavtal med det vetenskapliga förlaget Elsevier. Det innebär att svenska forskare nu åter får tillgång till förlagets drygt två tusen tidskrifter. Dessutom kommer alla svenska forskningsartiklar kunna publiceras omedelbart öppet tillgängligt (open access). Läs mer här.

https://www.lupop.lu.se/article/nytt-avtal-med-elsevier - 2025-11-06

Today, FORMAS announced the urgent grants for 2018 Last day of application: Any time during the year, until 08/11/2018Day of decision: Continuously during the year, last day of decision is 15/01/2019An urgent grant application can be submitted for any scientific discipline; the humanities, natural sciences, social sciences and technological sciences, and may also include interdisciplinary approach

https://www.lupop.lu.se/article/formas-urgent-grants - 2025-11-06

Hur bör den svenska forskningspolitiken utformas för att stärka forskningen, bidra till att lösa dagens samhällsutmaningar och skapa ny kunskap för en klokare värld? Se en inspelning från Vetenskapsrådets konferens på Stockholm Waterfront 20 november. Läs mer här.

https://www.lupop.lu.se/article/forskningspolitiska-dagen-2019-0 - 2025-11-06

Work histories generally cover all jobs held for ≥1 year. However, it may be time and cost prohibitive to conduct a detailed exposure assessment for each such job. While disregarding short-term jobs can reduce the assessment burden, this can be problematic if those jobs contribute important exposure information towards understanding disease aetiology. New publication in Annals of work exposure and

https://www.lupop.lu.se/article/characterizing-short-term-jobs-population-based-study - 2025-11-06

There is a growing interest in using health care (HC) data to produce epidemiological surveillance indicators such as incidence. Typically, in the field of cancer, incidence is provided by local cancer registries which, in many countries, do not cover the whole territory; using proxy measures from available nationwide HC databases would appear to be a suitable approach to fill this gap. However, i

https://www.lupop.lu.se/article/sound-use-health-care-data-epidemiology-evaluation-calibration-model-count-data-application - 2025-11-06

The association between socio-economic position and health is believed to be mediated, in part, by psycho-social comparison of one’s situation with that of others. But with whom? Possibilities include family, friends, elites, or even those in other countries or in previous times. So far, there has been almost no research on whether the reference point matters. New publication in International Jour

https://www.lupop.lu.se/article/compared-whom-reference-groups-socio-economic-comparisons-and-self-reported-health-34-countries - 2025-11-06

The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey. New publication in Europea

https://www.lupop.lu.se/article/esc-eorp-euro-endo-european-infective-endocarditis-registry - 2025-11-06