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The tax laws of most developed countries are debt biased since firms can deduct interest on debt but not on equity. This bias is known to distort investment decisions. However, less is known about how the debt tax shield affects the ownership of assets when bidders differ financial expertise and thus in optimal use of leverage. We show that the debt tax shield need not always distort ownership eff
Using a dataset with over 24 million year-employment observations and the universe of more than 230,000 entries into entrepreneurship in one economy we analyze the gross (including the founders), net (excluding the founders), and new (jobs to the former unemployed or those outside the labor force) job creation by entrepreneurs two and six years after start-up. These novel measures of job creation
I study the internal organization of firms using Swedish occupation data. The empirical patterns match the theoretical predictions of Caliendo and Rossi-Hansberg (2012) and are similar to the patterns observed in French data by Caliendo etal. (2012).
In industries with network effects, incumbents' installed bases create barriers to entry that discourage entrepreneurs from developing new innovations. Yet, entry is not the only commercialization route for entrepreneurs. We show that the option of selling to an incumbent increases the innovation incentives for entrepreneurs when the network effects are strong and incumbents compete to preemptivel
We extend the workhorse model of network competition to international calls. This model enables us to show that national regulatory authorities (NRAs) maximizing domestic welfare have incentives to increase termination rates above the social optimum to extract rent from international call termination. Excessive termination rates distort prices but transfer surplus from foreign to domestic consumer
Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration.Theory and Methods: Spoiled gradient echoes can be used to estimate whole-brain maps ofT1. This can be accomplished by using only two acquisitions with different flip angles, i.e., aDFA-based approach. Although DFA-based Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at 7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration. Theory and Methods: Spoiled gradient echoes can be used to estimate whole-brain maps of T1. This can be accomplished by using only two acquisitions with different flip angles, i.e., a DFA-based approach. Although DFA-ba
Throughout human history, there have been locations used for performance of speech and music. Many of these locations are considered part of our common cultural heritage, and more and more of them can be visited virtually as technology advances to produce better and better reconstructions. However, the technological capabilities are not the only limitations when it comes to historical reconstructi
Traditionally, the room acoustic properties in an ordinary public room are defined by only one parameter, the reverberation time. However, research has showed that additional room acoustic parameters as sound strength and speech clarity are necessary to consider in order to achieve good acoustic conditions. In a room with acoustical ceiling treatment the effects of furniture and interiors on the r
The year 1937 saw the establishment of Congress Ministries in eight of the eleven provinces in which the provincial elections had been held, Bihar being one of them. The resounding victory of the Congress which secured a clear majority in the province of Bihar and the dismal performance of the Muslim League seemed at the time to depict the mood of the people in general. It was taken as a clear rej
Background: Pulmonary arterial hypertension (PAH) is a serious disease exhibiting unspecific symptoms, as a result of which diagnosis is often delayed and prognosis is poor. The underlying pathophysiology includes vasoconstriction and remodelling of small pulmonary arteries. As receptor tyrosine kinases (RTKs) and their ligands have been shown to promote PAH remodelling, our aim was to evaluate if
We aimed to describe and evaluate the National Early Warning Score (NEWS) in the 24 hours preceding an in-hospital cardiac arrest among general somatic ward patients.The 24 hours preceding the in-hospital cardiac arrest were divided into four timespans and analysed by a medical record review of 127:254 matched case-control patients. The median NEWS ranged from 3 (2-6) to 6 (3-9) points for cases v
AIMS & OBJECTIVES: Describe Registered Nurses (RN) perceptions and experiences of and barriers for using the National Early Warning Score (NEWS) in relation to their work experience and medical affiliation.BACKGROUND: Indications of inconsistencies in adherence to the NEWS has emerged.DESIGN: Web-based questionnaire study.METHODS: The questionnaire was sent to 3,165 RNs working in somatic hosp
PURPOSE: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU.METHODS: This prospective study included intensive care patients aged ≥ 80 years in 309 ICUs from 21 European countries with 30-day mortality follow-up.RESULTS: LST limitation was identified in 1356/5021 (27.2%) of patients: 15% had a withho
BackgroundDeviating vital signs have been known to precede Serious Adverse Events (SAEs) like In-Hospital Cardiac Arrest (IHCA), unplanned Intensive Care Unit (ICU) admission or unexpected death for more than a decade but still the recognition of these deteriorating patients is poor.The British National Early Warning Score (NEWS) is a ‘‘track and trigger’’ scale designed to assess in-hospital patiBackgroundDeviating vital signs have been known to precede Serious Adverse Events (SAEs) like In-Hospital Cardiac Arrest (IHCA), unplanned Intensive Care Unit (ICU) admission or unexpected death for more than a decade but still the recognition of these deteriorating patients is poor.The British National Early Warning Score (NEWS) is a ‘‘track and trigger’’ scale designed to assess in-hospital pati
Precise regulation of dNTPs within the cellular nucleotide pool is essential for high accuracy of DNA replication and is critical for retaining the genomic integrity. Recently, human dCTPase (deoxycytidine triphosphatase), also known as DCTPP1 (human all-alpha dCTP pyrophosphatase 1) has been revealed to be a key player in the balance of pyrimidine nucleotide concentrations within cells, with DCTP
According to a recent conjecture in the literature, earnings have become a poorer proxy for cash flow from operations over time. We find that since 1988, when cash flow statements started to be consistently reported in Compustat, the cash effectiveness of earnings has actually increased for a large sample of U.S. manufacturing firms. This occurs despite the introduction of fair value accounting an
