Background: Growth differentiation factor 15 (GDF-15) has been associated with the risk of developing major bleedings, including but not restricted to intracranial hemorrhages, in patients on oral anticoagulants or dual antiplatelet therapy. We hypothesized that there may be an association of GDF-15 with incidence of hemorrhagic strokes in the general population, which has not been investigated be

Background: There has been a global increase in the number of people who are dying of old age. This development implies a need for good palliative care among older persons at the end of life. Here nursing homes have an important role to play. However, the principles of palliative care have not been sufficiently applied in nursing homes, and there is a need to increase the implementation of palliat

Review of Anna-Maija Multas PhD thesis from 2022: New health information literacies. A nexus analytical study. Acta universitatis OuluensisB Humaniora 192, University of Oulu, Oulu

Convection-enhanced delivery as a means to deliver therapeutic drugs directly to the brain has shown limited clinical efficacy, primarily attributed to the phenomena of backflow, in which the infused fluid flows preferentially along theshaft catheter rather than forward into the tissue. We have previously developed a finite element model of backflow that includes both material and geometric nonlin

The focus and instruments of innovation policy have changed fundamentally over the last decades. Recently transformative innovative policy has caught the attention of scholars and policymakers, who argue that this is a new shift in the policy discourse. Even though grand challenges such as global warming and migration flows, as well as technological change such as artificial intelligence and indus

This paper considers the unfolding of Smart Specialisation Strategy (RIS3) in one of Europe’s innovation-leading metropolitan regions: Stockholm, Sweden. Theoretically, it contributes to debates around change agency and reflects more broadly, which implications arise for metropolitan innovation-leader regions and which are of more generic nature. It argues that actor endowments, dense networks, ex

This thesis investigates the interactions that occur in extreme densities for high-energy collisions of subatomic particles. The theoretical models developed for this purpose are based on the Lund model. The developments have been implemented as a new module called Gleipnir to the Monte-Carlo event generator, P YTHIA . The two models developed are string shoving and rope hadronization, and can now

Biografi om drottning Sofia av Sverige, maka till kung Oscar II.

Artificial moral agents must not only be able to make competent ethical decisions, but they must do so effectively. This paper explores how ethical theory and algorithmic design impact computational efficiency by assessing the time cost of ethical algorithms. We create a model of an ethical environmentand conduct experiments on three different ethical algorithms in order to compare computational b