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Background: Previous gene-environment interaction studies of breast cancer risk have provided sparse evidence of interactions. Using the largest available dataset to date, we performed a comprehensive assessment of potential effect modification of 205 common susceptibility variants by 13 established breast cancer risk factors, including replication of previously reported interactions. Methods: Ana

Structure-activity relationships for chain-shortened analogs of (Z)-5-decenyl acetate, a pheromone component of the turnip moth, Agrotis segetum, have been studied by electrophysiological single-sensillum technique and interpreted in terms of a previously reported receptor-interaction model. The results indicate that the terminal methyl group, as well as the acetate group, interacts with highly co

The female sex pheromone composition and the male electro-physiological response with respect to the three main sex pheromone components, (Z)-5-decenyl acetate, (Z)-7-dodecenyl acetate, and (Z)-9-tetradecenyl acetate, were investigated in populations of Agrotis segetum from Armenia and Bulgaria. The percentage composition of the female-produced pheromone was 1:52:47 and 1:42:57 for the respective

The sex pheromone of females of the carob moth, Ectomyelois ceratoniae, was identified to be a mixture of (Z,E)-9,11,13-tetradecatrienal, (Z,E)-9,11-tetradecadienal and (Z)-9-tetradecenal in the ratio of 10:1:1. A synthetic blend proved to be attractive. GC/EAD + GC/MS investigations showed (Z,E)-9,11,13-tetradecatrienal, (Z,E)-9,11-tetradecadienal and (Z)-9-tetradecenal to be the sex pheromone of

Males reared on artificial diet as larvae or starved as adults contained lower amounts of the behaviourally most active courtship pheromone component ethyl trans-cinnamate, but no difference in mating success between apple-reared and diet-reared males could be demonstrated. -from Authors

The E and Z pheromonal strains of the European corn borer, Ostrinia nubilalis, are characterized by female production of and male preference for opposite blends of (E)-11-and (Z)-11-tetradecenyl acetate. It is known that the pheromone production is controlled by an autosomal gene and that the males' behavior is determined by a sex-linked gene. A third gene, autosomally inherited, has been shown to

The olfactory response from male pheromone sensitive sensilla was investigated in the endemic New Zealand brownheaded leafrollers Ctenopseustis obliquana (Walker) and C. sp. ‘ropeana' (Lepidoptera, Tortricidae). The responses from 281 sensilla from the parental strains and from both the reciprocal crosses, including F1, F2 and maternal and paternal backcrosses were recorded, and statistically anal

Recordings of the firing rates of single antennal neurons when Agrotis segetum antennac were placed 70 cm downwind of a pheromone source revealed that cells sensitive to the most volatile component adapted rapidly in a plume from a high-concentration source known from previous studies to cause in-flight arrestment of progress towards the source. No adaptation was found in response to lower-concent

Four compounds, tetradecyl acetate, (Z)‐9‐tetradecenyl acetate, (E)‐11‐tetradecenyl acetate and (Z)‐11‐tetradecenyl acetate were identified from female sex pheromone extracts of Hungarian and Egyptian lima‐bean pod borers (Etiella zinckenella Tr., Lepidoptera: Phycitidae) by gas chromatography with flame ionization (FID) and electroantennographic (EAD) detection. In EAG studies these monounsaturat

First meiotic division in females and males of Yponomeuta evonyrnellus (L.), Y. cagnagellus (Hiibner). Y. rnalinellus Zeller, Y. padellus (L), Y. rorellus (Hiibner) and Y. gigas Rebel was studied in the light microscope. In the heterogametic females the sex chromosomes were found to be associated in a sex chromosome trivalent. The sex chromosome trivalent, written AA W Z, consisted of a W‐chromos

The European Union's Natura 2000 (N2000) is among the largest international networks of protected areas. One of its aims is to secure the status of a predetermined set of (targeted) bird and butterfly species. However, nontarget species may also benefit from N2000. We evaluated how the terrestrial component of this network affects the abundance of nontargeted, more common bird and butterfly specie

The introductory chapter emphasises the general relevance of the study of electoral candidates in representative democracies. It presents the book’s theoretical framework: the triadic delegation and accountability relationship between candidates, voters and parties—based on principal–agent theory. We theoretically map patterns of candidates’ behaviour and attitudes in all main dimensions of their

In the concluding chapter, we outline the major findings from the eleven book chapters by connecting them to one another. We come back to the triadic delegation and accountability relationship between candidates, voters and parties that were developed based on principal–agent theory, and emphasise the most relevant findings of this book that inform this triad. The chapter also takes a critical sta

The paper focuses on analysis of macro‐ and micromorphological characteristics of relict slope deposits in Serra da Estrela (Portugal) to understand the significance of different slope processes and paleoenvironmental settings. Micromorphology is a useful sedimentology technique allowing significant advances compared to macroscopic techniques. Results show that different processes are involved in

Big Science is costly and complex, and historical evidence seems to suggest that projects often get delayed and more expensive than planned. On the basis of several studies of large infrastructures such as railroads and bridges, the Danish geographer Bent Flyvbjerg has proposed that there is an “iron law” of megaprojects, meaning that they almost without exception turn out more expensive and more