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Pharmacodynamics of amoxicillin/clavulanic acid against Haemophilus influenzae in an in vitro kinetic model: a comparison of different dosage regimens including a pharmacokinetically enhanced formulation

OBJECTIVE: To study the pharmacodynamics of amoxicillin/clavulanic acid against different strains of Haemophilus influenzae in an in vitro kinetic model. The concentrations used corresponded to human serum levels obtained after 875 mg amoxicillin/clavulanic acid given b.i.d., 500/125 mg amoxicillin/clavulanic acid given t.i.d. and those obtained with a pharmacokinetically enhanced formulation cont

Developing knee joint osteoarthritis: Clinical, radiographical and biochemical features.

Popular Abstract in Swedish Knäledssmärtor och knäledsartros: kliniska, röntgenologiska och biokemiska undersökningar under tidig artrosutveckling Långdragna knäsmärtor (dagligen i mer än 3 månader) förekommer hos 15 % av personer i åldern 35-54 år. Det visar vår undersökning av befolkningen i Laholms kommun i sydvästra Sverige. En orsak till långdragna knäsmärtor kan vara artros (s.k. broskförThe aim of this project was to study clinical, radiographical and biochemical features of developing, symptomatic knee osteoarthritis (OA) prospectively in individuals aged 35-54 from the general population. A questionnaire to a random sample of 2 000 individuals in the district of Laholm, Sweden, identified 279 individuals (15% of the population) with chronic (>3 months) knee pain. Of these, 204

The expression and function of protein kinase C isoforms in differentiating neuroblastoma cells

The human neuroblastoma cell line SH-SY5Y can be induced to differentiate into a neuronal sympathetic phenotype after treatment with 16 nM 12-O-tetradecanoyl phorbol 13-acetate (TPA) in serum, or by a combination of the growth factors basic fibroblast growth factor and insulin-like growth factor-I (bFGF/IGF-I). SH-SY5Y cells stably transfected with TrkA, the nerve growth factor (NGF) receptor, dif

Exploring the Possibilities of 14C Bomb-Pulse Dating of Human Tissue Samples

Popular Abstract in Swedish Levande organismer, inklusive människor, har en 14C/12C-kvot som återspeglar miljön. När materialet dör slutar kroppen att fylla på 14C och kroppens 14C börjar sönderfalla till 14N. Detta gav upphov till den klassiska 14C-dateringsmetoden, vilken utvecklades av professor W.F. Libby, 1949 och gav honom Nobelpriset i kemi 1960. 14C-datering används huvudsakligen inom arkeThe testing of nuclear weapons in the atmosphere, in the middle of the 20'h century, resulted in a bomb-pulse excess of atmospheric 14C. A bomb-pulse dating method was thus developed. The latter is a method to determine the time of formation of formerly living modern (i.e. living after 1955) material , based on the 14C/ 12C ratio in it. The objective of this work was to evaluate the factors that c

The Useworthiness of Robots for People with Physical Disabilities

Popular Abstract in Swedish Avhandlingen behandlar robotteknik och de nya möjligheter som den kan ge människor med rörelsehinder. Jag fokuserar på teknikanvändaren och teknikanvändningen, speciellt på vad som gör robothjälpmedel värda att använda. Distinktion görs mellan användvärdhet och användbarhet. Erfarenheter från användning av den rullstolsmonterade robotarmen Manus visar att tekniska kravThis thesis deals with robotics and the new possibilities it offers people with physical disabilities. I focus on the user and the use of the technology and, in particular, on what makes robotic aids worth using - useworthiness as distinguished from usability. User experience of the wheelchair-mounted Manus manipulator shows that robotic arms must meet technical requirements in terms of accelerat

Grön offentlig upphandling

This master thesis deals with the general questions of how and when environmental considerations can and may be regarded during a public procurement process. Green public procurement has developed from being something viewed with suspicion to becoming a definite and promoted instrument by Law and politicians. This paper reviews the possibilities and pitfalls of green public procurement according

Comparative analysis of the understanding of 'expertise' and 'resilience' in novice and expert anesthesiologists

Anesthesiology is the medical specialty dedicated to the relief of pain and care of the surgical patient before, during and after surgery. Most of the work in anesthesiology is routine patient care, but because patients are sick and surgical procedures may develop in unexpected ways, anesthesiology by its nature often involves medical crises. In recent years, two concepts have gained increasing i

Att offras eller att inte offras

Examensarbetets titel: “Att offras eller att inte offras”. En kvalitativ intervjustudie som undersöker konsumenters uppfattning av scapegoating i form av VD:ns avgång i samband med en kris och dess påverkan på varumärken Seminariedatum: 2021-02-06 Kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 högskolepoäng Författare: Anna Sahlberg Carlsson, Beatrice Molin, Casper Tönning Handl

Omklassificering av differentierad utdelning - Beaktas tillämpligheten av 57 kap. IL vid omklassificering av differentierad utdelning till löneinkomst?

Genom den svenska skattereformen år 1990–91 skapades ett dualistiskt skattesystem där kapitalinkomster och tjänsteinkomster beskattas separat. Omarbetningen syftade till att minska möjligheterna för skatteplanering samt att öka rättvisan i systemet. Dessvärre har syftet ej uppnåtts. Beskattning av kapitalinkomster är jämförelsevis lägre vilket givit incitament att inkomstomvandla. För att beivra iSince the tax reform in Sweden, 1990–1991, earned income and capital income has been separated into a dual income tax system. The purpose of the reform was to reduce the opportunities for tax planning and to increase the justice of the system. Unfortunately, the purpose has not been achieved. To prevent income shifting from earned income to capital income the legislature legislated special legal r

Feasibility of adaptive SBRT of prostate cancer: Investigating uncertainties in AI-driven and CBCT-guided online adaptive radiotherapy

Cancer kan drabba vem som helst och kan ha sitt ursprung i många olika områden i kroppen. Antalet nya cancerfall ökar varje år, men vissa typer av cancer har bättre prognos än andra. Den vanligaste cancertypen i Sverige är prostatacancer och den drabbar framför allt äldre män. Prostatacancer har god prognos och det finns effektiva metoder att helt bota prostat- acancer om den behandlas i ett tidigPurpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB

Självförsörjande flerbostadshus

I takt med att världen blir mer medveten om hur människans beteende påverkar jordens klimat, ställs också högre miljömål. Ett hållbart energisystem är en del av dessa miljömål och att övergå till enbart förnybara energikällor är ett verktyg för att uppnå dessa. Övergången till endast förnybara energikällor riskerar dock att medföra problem, bland annat så kallad effektbrist. Effektbrist är inget nAs the world becomes more aware of how human behavior affects the earth’s climate, higher environmental goals are also set. A sustainable energy system is one part of these environmental goals, and switching to only renewable energy is a tool to reach such goals. However, a system with only renewable energy can be vulnerable at time periods of reduced production of electricity, with a subsequent r

Chemical composition of the Pulp and Seed Kernels of Baobab fruits from three different African Countries

The baobab is among the commonly consumed wild fruits found in the semi-arid regions of sub-Saharan Africa. It has a wide application in food systems and folk medicine and has an advantage of surviving even in harsh environmental conditions. While the fruit pulp is packed with a lot of essential nutrients and has gained much interest in recent past on the international market as a healthy ‘superfo

Information Management in Kockums AB´s Supply Chain regarding Development Products - Drivning Forces and Barriers to reach excellence

Title: Information Management in Kockums AB’s Supply Chain regarding Development Products – Driving Forces and Barriers to reach excellence
Authors: Fredrik Arborelius and Henrik Stenvinkel
Supervisors: Anders Jansson, Manager Design Support and Tactical Planning, Kockums AB
Dag Näslund, Associate Professor, Department of Industrial Management and Logistics, Lund Institute of Technolog

Psychosocial consequences of false-positive mammography among women attending breast cancer screening. Assessment, prediction, and coping.

Popular Abstract in Swedish Bröstcancer är den vanligaste dödsorsaken bland cancersjuka kvinnor. Därför rekommenderas regelbundna mammografiska hälsokontroller för tidig diagnostik och snar behandling för att förbättra prognosen. I Sverige rekommenderas kontroller för kvinnor mellan 40-74 år. Mammografiska hälsokontroller medför dock även risker, såsom till exempel behov av kompletterande bröstundOne side-effect of breast cancer (BC) screening is a false-positive mammogram among healthy women. That is, finding(s) on a screening mammogram that lead to additional breast examinations but where the woman is eventually considered free from BC. There is evidence of short-term psychosocial consequences of false-positive BC screening. Regarding long-term consequences, research findings are inconsi

Upper Cambrian trilobite faunas and biostratigraphy at Kakeled on Kinnekulle, Västergötland, Sweden

Populärvetenskaplig sammanfattning: I Kakeled på Kinnekulles sydvästsluttning, Västergötland, finns en blottad lagerföljd från överkambrium. Överkambrium är en tidsperiod som sträckte sig från ca 525 till 500 miljoner år sedan. Avsättningen i det överkambriska havet var extremt långsam (1-10 mm/1000 år). Bottenförhållandena var mer eller mindre syrefria, varför nedbrytningen av det organiska materUpper Cambrian strata are well exposed in an old quarry at Kakeled on south-western Kinnekulle, south-central Sweden. The exposures consist of finely laminated alum shale with lenses and beds of dark grey limestone (stinkstone or orsten), and a few thin layers of sandstone. A 6.20 m thick section in the central part of the quarry has been measured and sampled in order to establish the succession o

Thrombolysis for lower extremity bypass graft occlusion

Background: Thrombolysis is a common method in the treatment of lower extremity bypass graft occlusion. The purpose of this study was to investigate the results of thrombolytic therapy in the management of acute bypass graft occlusion and to identify risk factors for technical failure and amputation. Methods: All patients at two tertiary referral centers undergoing thrombolysis for acute graft occ

Swedish State Monopolies and their Compatibility with EC Law

The principal rule of the common market is that goods and services are able to move freely across the borders of Member States. State monopolies in control of supply and demand are, therefore, only under exceptional circumstances compatible with the conditions of the common market. The compatibility of Swedish State monopolies with EC law is a controversial matter. The case-law of the ECJ lets us