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The role of glycoprotein 2 in an enteric Salmonella infection model

Glykoprotein 2 – att skydda eller inte skydda, det är frågan. Glykoprotein 2 (GP2) är ett medfött protein som huvudsakligen produceras i bukspottkörteln och även finns på specialiserade tarm-epitelceller. Det delar likheter med ett annat protein som kallas för Tamm-Horsfalls protein (THP). Båda kan interagera med bakteriella fimbrier tex E. coli och Salmonella. THP kan därmed förhindra att E. coGlycoprotein 2 (GP2) is a glycosylphosphatidylinositol (GPI)-anchored protein primarily produced by pancreatic acinar cells. It is expressed on M cells and can interact with the type 1 fimbrial adhesin (FimH), a component of type 1 pili found in gram-negative bacteria e.g Salmonella. It shares homology to Tamm-Horsfall protein (THP) which has been shown to have antibacterial effects and can also i

Extending the resolution of conventional deep seismic 3D surveys

Ny teknik på företaget Maersk Oil har möjliggjort en effektivare avbildning av den ytnära berggrunden som tidigare förblivit dolda. Denna nya metod leder förhoppningsvis till en mer säker kartläggning av geologiska risker. Ett viktigt framsteg där både liv och miljö kan sparas. Tänk dig en exploderande oljerigg, orsakat av att någon ovetandes borrat rakt in i en gasficka i den ytnära berggrunden.The main objective of this master's thesis is to evaluate a new processing method for extracting seismic conventional 3D streamer deep target data for shallow subsurface imaging. Deep target acquisitions have greater potential than it's conventional use. The aim of these acquisitions is to discover natural resources, in particular oil and gas, at several kilometres of depth. Before drillin

Tip enhanced Raman spectroscopy vs. micro-Raman spectroscopy of InP/InGaP axially heterostructured nanowires for tandem solar cells

We present a Raman study of axially heterostructured InP/InGaP nanowires (NWs) for tandem solar cells. The study is carried out using both microRaman spectroscopy (µ-Raman), and tip enhanced Raman spectroscopy (TERS). The results obtained by both methods are compared. The results obtained with each one is supported by the simulation of the light/NW interaction using finite element methods. This si

Photosynthetic Oxygen Evolution - EPR studies of the manganese cluster of photosystem II

Popular Abstract in Swedish Fotosyntesen är den mest grundläggande förutsättningen för människans överlevnad. Genom att absorbera solenergi och omvandla den till kemiskt bunden energi i form av energirika organiska molekyler, står fotosyntesen för nästan all tillförsel av energi till vårt ekosystem. Energin utnyttjas som mat, till oss och till djuren vi beror av, och som bränsle, fossilt eller färIn this thesis, a new electron paramagnetic resonance (EPR) signal from photosystem II is presented. The signal is shown to originate from the S0 oxidation state of the oxygen-evolving complex (OEC). It is a Mn-derived signal displaying clear hyperfine structure, centered at g=2, and is significantly broader than the well-known multiline signal from the S2 state, indicating the presence of MnII in

Identifying and modelling clinical subpopulations from the Malmö breast tomosynthesis screening trial

Virtual Clinical Trials (VCT) are an effective tool to evaluate the performance of novel imaging systems using computer simulations. VCT results depend on the selection of virtual patient populations. In the case of breast imaging, virtual patients should be matched to a desired clinical population in terms of selected anatomical or demographic descriptors. We are developing a virtual population o

Utilization of healthcare and prescription medicines after non-pharmacological interventions for depression - A 3-year register follow-up of an RCT in primary care

Depression is a common, recurrent disorder. There is a need for readily available treatments with few negative side effects, that demands little resources and that are effective both in the short- and long term. Our aim was to investigate the long-term effectiveness of two different interventions; physical exercise and internet-based cognitive behavioural therapy (internet-CBT), compared to usual

RIFM fragrance ingredient safety assessment, 2-Methyl-3-buten-2-ol, CAS Registry Number 115-18-4.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential as well as environmental safety. Repeated dose, developmental, and reproductive toxicities were determined to have

RIFM fragrance ingredient safety assessment, allyl phenylacetate, CAS registry number 1797-74-6.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated Dose Toxicity was determined to have the most conservative systemic e

RIFM fragrance ingredient safety assessment, α-irone, CAS registry number 79-69-6.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential as well as environmental assessment. Repeated Dose Toxicity was determined to have the most conservative systemic e

RIFM fragrance ingredient safety assessment, ethyl anthranilate, CAS registry number 87-25-2.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Reproductive toxicity was based on the Threshold of Toxicological Concern (TTC

Fast and High-Quality Visibility Determination

Popular Abstract in Swedish Datorgenererade bilder är en viktig del av underhållningsindustrin, som bland annat innefattar spel- och filmindustrin. För att kunna skapa avancerade specialeffekter i filmer samt stora och detaljerade spelvärldar krävs datorprogram som utnyttjar beräkningskraften i dagens datorer på ett effektivt sätt. Bättre och snabbare datorprogram leder ofta till nya användaruppleComputer generated imagery is vital to the entertainment industry in the production of games and films, for example. It is also increasingly important for visualization in design, architecture, engineering, and medicine, to name a few. Improvements to rendering techniques come from a combination of improved algorithms and more powerful hardware. Typically, hardware developments introduce new chall

RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated dose toxicity was determined to have the most conservative systemic e

RIFM fragrance ingredient safety assessment, l-Borneol, CAS registry number 464-45-9.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated Dose Toxicity was determined using read across analog to have the mos

RIFM fragrance ingredient safety assessment, Benzyl propionate, CAS Registry Number 122-63-4.

The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential, as well as, environmental safety. Repeated dose toxicity was determined to have the most conservative systemic exp