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Objectives. This study aimed to estimate the prevalence of atrial fibrillation (AF) and identify its associated comorbidities in adults aged 45 years and older, using data from the Swedish general population study EpiHealth. Design. In a cross-sectional design, data of health history, lifestyle factors, anthropometric measurement, and 1-lead ECG recordings from participants in the EpiHealth study

Nanowires are promising structures for next-generation photonic devices due to their superior structural, optical, and electronic properties compared to thin films. In this study, unexpected electrostatic potential wells across the non-polar m-plane and at the core/shell interface in n-type GaN core/shell nanowires, grown via metal-organic vapor phase epitaxy, are reported. Using advanced electron

Violent offenders are a heterogeneous group where criminogenic needs often are substantial and violent behaviors persistent. Risk, Need, and Responsivity (RNR)-based treatment has shown effect on reducing the risk for recidivism in violent crime, but the development of novel treatments is crucial in making the change process more effective. Virtual Reality (VR) technology may be a tool to improve

Lead-free perovskites (LFPs) are an emergent class of materials with great potential as next-generation candidates for energy and optoelectronic applications, offering a sustainable and non-toxic alternative to their lead-based counterparts. Computational studies play a central role in accelerating the discovery, design, and optimization of these materials by enabling predictive insights into elec

This study explores structural modifications for reducing train-induced vibrations in timber buildings by modifying the building layout. A parameter study was conducted using a semi-analytical ground model coupled with a finite element structural model. The train load was modeled as a stationary oscillating point load of unit magnitude, applied on the ground surface. The analyzed frequency range,

High efficiency, low total harmonic distortion (THD), and near-unity power factor are essential for low voltage battery charging systems to satisfy modern power quality requirements. In this study, an isolated totem-pole power factor correction (PFC) integrated buck converter has been designed and analyzed for low-voltage battery charging applications. The proposed topology combines a bridgeless t

The primary regulator of testicular function is the gonadotropin-releasing hormone (GnRH). This hormone is secreted in a pulsatile manner by hypothalamic neurons. GnRH stimulates the synthesis and secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland. LH stimulates the synthesis of testosterone (T) after binding to specific receptors on Leyd

The European Union (EU) has recently presented several new legal proposals for promoting ecodesign and product labeling. The aim is to harmonize national practices and rules in the EU, to regulate issues like product lifetime and repairability in a more comprehensive way, to introduce new tools like digital product passports, and to introduce labeling schemes for repairability and durability. In p

Introduction: Vitamin D deficiency has previously been shown to be associated with cancer-related fatigue. If vitamin D deficiency affects fatigue in frail elderly has not been studied before. The aim of this study was to investigate associations between vitamin D, fatigue, frailty, and sarcopenia in frail elderly with cancer (FEC) and without cancer (FE) in comparison with healthy controls. Metho

Susceptibility testing of clinical multidrug-resistant (MDR) and reference P. aeruginosa strains was performed using the standard twofold serial dilution method. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of antiseptics were determined. MIC and MBC values were also interpreted as the bacteriostatic index of antiseptic activity (BSIAA) and the bactericid

Introduction: Postnatal pesticide exposure and its impact on executive functioning (EF) in children and adolescents remains underexplored, particularly in African agricultural contexts. This study investigated associations between urinary pesticide biomarkers and EF in the Child health Agricultural Pesticide study in South Africa (CapSA). Methods: Data from 445 participants (mean age: 10.6 years;

Background: Early-life growth adversity is important to later-life health, but precision assessment in adulthood is challenging. We evaluated whether the difference between attained and genotype-predicted adult height (“height-GaP”) would associate with prospectively ascertained early-life growth adversity and later-life all-cause and cardiovascular mortality. Methods: Data were first analyzed fro

BackgroundOsteocalcin is a bone-specific protein involving many physiological processes, primarily bone turnover. Also closely related to the musculoskeletal system is the frailty syndrome.AimTo investigate if circulating osteocalcin levels and frailty are associated in the old, and in addition, if the presumed association is mediated through alterations in bone.Methods999 community-dwelling women

Fler än 800 000 svenskar har privata sjukvårdsförsäkringar, men effekten detta har på svensk sjukvård och jämlikhet går inte att följa i svenska register.

Aim: Assess healthcare utilization and direct costs for heart failure (HF) during the first two years post-diagnosis across HF subgroups. Methods: This retrospective population-based study included patients with HF aged 40–90 years in Region Halland. HF subgroups were defined based on echocardiographic ejection fraction, including HF with reduced ejection fraction (HFrEF), mildly reduced ejection

Introduction: The importance of measuring vascular age has been emphasized in numerous studies, highlighting its critical role in precision medicine. This cross-sectional heterogeneity exploration study examined sex- and country-specific association of serum uric acid (SUA) and inflammation, measured as high sensitivity C-reactive protein (hs-CRP), and vascular aging across populations with divers

Background: Nocturnal hypoxemia commonly affects people with pulmonary fibrosis (PF). Research Question: What are the current practices for assessment of sleep and nocturnal hypoxemia in PF, and what are the research priorities and outcome measures of importance for nocturnal oxygen therapy (NOT)? Study Design and Methods: People with PF and health care professionals (HCPs) with expertise in PF, s

BACKGROUND: A growing body of evidence links microRNAs (miRNAs) to major depressive disorder (MDD). However, the causal nature of these associations remains unclear.OBJECTIVES: This study aimed to investigate the potential causal association between miRNAs and MDD by combining Mendelian Randomization (MR) analyses and experimental validation.METHODS: Single-nucleotide polymorphisms (SNPs) signific

Introduction: Implementing new treatment regimens entails a learning phase with a concomitant risk of suboptimal results. High caseload has generally been shown to improve results in complex surgical procedures. This study aimed to evaluate results of Cytoreductive Surgery (CRS) and Intraperitoneal Chemotherapy (IP), given as Early Postoperative Intraperitoneal Chemotherapy (EPIC) or Hyperthermic

Objectives: To evaluate the test–retest reliability of a novel laboratory-based protocol for inducing and measuring head acceleration in multiple directions under anticipated and unanticipated conditions. Design: Laboratory-based test–retest reliability study. Methods: Thirty physically active adults (50% female) completed standardized head perturbations using a custom-built apparatus. Perturbatio