AIMS: To assess the effect of metformin on insulin sensitivity, glucose tolerance and components of the metabolic syndrome in patients with impaired glucose tolerance (IGT). METHODS: Forty first-degree relatives of patients with Type 2 diabetes fulfilling WHO criteria for IGT and participating in the Botnia study in Finland were randomized to treatment with either metformin 500 mg b.i.d. or placeb

I denna samlingsvolym belyser några svenska religionsvetenskapliga forskare hur religion, kön och makt som oupplösligt förenade begrepp berör varandra ur religionsfilosofiska perspektiv. Religion kan inte uttömmande beskrivas utan att dess hierarkiska strukturer och dess roll som maktfaktor i samhället berörs. Förhållandena mellan könen formuleras ofta i religiösa termer och underliggande maktaspe

In this study two groups of children were compared, 192 bilingual and 246 monolingual, referred over a 12-mo period to University Hospital in Malmö for suspected language impairment. Compared with monolingual children, bilingual children ran a significantly lower risk (RR = 0.76, p < 0.0001) of being referred by a child health centre, and a significantly higher risk (RR= 1.54, p < 0.0103) of being

Calreticulin is a Ca2+-binding chaperone localized mainly in the endoplasmic/sarcoplasmic reticulum in all higher organisms. To date, only one calreticulin isoform has been identified in human and mouse. Here we report a novel calreticulin isoform (Crt2) in human and mouse, with 53 (human) and 49% (mouse) identity to the previously identified calreticulin in respective species. The gene encoding t

The creation spectra of F centres by synchrotron radiation of 5-35 eV have been measured for Na6Al6Si6O24(NaI)(2x) and Na6Al6Si6O24(NaBr)(2x) optical ceramics at 8 and 80 K. The exciting photons cause the excitation and ionization of halogen ions (6-8 eV) and of an aluminosilicate carcass (8.5-31 eV) or the excitation of Na+ ions (32-35 eV). An exciting photon of 20-26 and 27-31 eV creates two or

The development of alternative treatment regimens in clinical oncology has increased the need for early prediction of cancer therapy outcome. The aim of this study was, early in the treatment phase, to identify patients with advanced head and neck cancer, responding or not responding to initiated therapy. The tumour metabolic rate of glucose (MRgl) examined by 2-18FDG-PET was determined in 17 pati

Aims. This paper presents a new homogeneous catalogue of blue straggler stars ( BSS) in Galactic open clusters. Methods. Photometric data for 216 clusters were collected from the literature and 2782 BSS candidates were extracted from 76 of them. Results. We found that the anticorrelation of BSS frequency vs. total magnitude identified in similar studies conducted on Galactic globular clusters exte

Aggrecans and PG-M/versicans represent two newly defined families of hyaluronan-binding proteoglycans for which the function is still poorly understood. Using the avian neural crest as a model system, we have examined the molecular mechanisms entailed in the cell-proteoglycan interaction during embryonic cell motility. Both the primary cartilage aggrecan of the avian embryo (PG-H/aggrecan) and the

We have measured radiative lifetimes of ten Th II levels by using thelaser-induced fluorescence technique and branching fractions withFourier transform spectroscopy. By combining the new branching fractionswith a total of 23 lifetimes, from the present work and frommeasurements by Simonsen et al. (cite{Simonsen}), absolute oscillatorstrengths for 180 lines have been derived. Some of these new f-va

Forms of res judicata - Unwritten principle of EU law - National procedural autonomy v. EC supremacy - Revision of decisions v. state liability - Finality of administrative decisions v. judicial decisions - Higher respect for judicial decisions than for administrative decisions - Res judicata not absolute - ECJ itself under demands of legal certainty - Analogy between res judicata rules and rules

OBJECTIVE: To explore the feasibility of prospectively monitoring treatment efficacy and tolerability of infliximab, etanercept, and leflunomide over a two year period in patients with established rheumatoid arthritis (RA) in clinical practice using a structured protocol. METHODS: All patients with RA at seven centres in southern Sweden, for whom at least two disease modifying antirheumatic drugs,

The first paper in this study is "Cassel and Revealed Preference Theory." The background to the paper is the general agreement that P. Samuelson originated the revealed preference theory of consumer behaviuor in 1938, but that there has not been such unanimous consent regarding possible precursors of the theory. Among those pointed to as predecessors is Cassel. This claim is, however, not so easy

This study of stress-related antinuclear antibody (ANA) reactivity was undertaken with the objective of improving clinical ANA testing. ANA was determined by parallel enzyme-linked immunosorbent assays of crude nuclear protein antigen extracted from HEp-2 cells either grown under optimal conditions (providing nonstress ANA antigen) or exposed to stress (providing stress ANA antigen). The stress st