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Biliary tract cancers (BTC) are rare and often diagnosed in late stages with advanced, nonresectable disease. The targeted agents panitumumab and bevacizumab have shown promising outcomes in combination with chemotherapy in other gastrointestinal (GI) cancers. We wanted to investigate if panitumumab or bevacizumab was the most promising drug to add to chemotherapy. Eighty-eight patients were rando

PURPOSE: Reliable molecular diagnostic tools are still unavailable for making informed treatment decisions and monitoring the response in patients with castration resistant prostate cancer. We evaluated the significance of whole blood circulating androgen receptor transcripts of full length (AR-FL) and splice variants (AR-V1, AR-V3 and AR-V7) as biomarkers of abiraterone acetate treatment resistan

Viruses are infections species that infect a large spectrum of living systems. Although displaying a wide variety of shapes and sizes, they are all composed of nucleic acid encapsulated into a protein capsid. After virions enter the host cell, they replicate to produce multiple copies of themselves. They then lyse the host, releasing virions to infect new cells. High proliferation rate of viruses

Background and purpose — Joint contracture is a common problem among children with cerebral palsy (CP). To prevent severe contracture and its effects on adjacent joints, it is crucial to identify children with a reduced range of motion (ROM) early. We examined whether significant hip, knee, or foot contracture occurs earliest in children with CP. Patients and methods — This was a longitudinal stud

Objective: To study the association between cardiovascular co-morbidities and mortality risk in primary care patients with atrial fibrillation. Methods: The study population included all adults (n = 12,283) ≥ 45 years diagnosed with AF at 75 primary care centres in Sweden between 2001 and 2007. The outcome was mortality (until 2010) and data were explored for co-morbidities using Cox regression wi

The aim of this essay is to examine which help a group of women with eating disorders had from thier treatment in daycare in 2004. The aim is to examine how the women have experienced this treatment and how they live today. The central questions are: what was their life situation like before the treatment, what was their experience of the treatment, how could the treatment have been better and how

The aim of this study is to further the understanding of the individual’s prospect to contribute politically in a global setting with the means provided as a consumer. Through a descriptive qualitative literature study the conception of political consumerism and the circumstances surrounding it is analyzed. All in the light of globalization and the decreased importance of nation-state boundaries.

Gröna tak kan minska problem med s.k. urban heat islands och kan användas för dagvattenhantering. Andra miljöfördelar som en förbättring av luftkvalitet, biodiversitet och bullerminskning finns också. Detta projekt fokuserar på lokala (kommunala) medel för att skapa en bättre miljö med extensiva gröna tak, vilka är nästan underhållsfria. Ett delområde i Lund som inkluderar Universitetet och UniverGreen roofs have the potential to mitigate problems with an urban heat island and to act as an element in stormwater management. Other environmental benefits exist as well, such as improvement of air quality, biological diversity and noise reduction. This project focuses on local community efforts to create a better environment through the use of extensive green roofs, which require almost no main

Inom både OECD och EU pågår samarbete för att motverka skadlig skattekonkurrens. OECD:s skattekonkurrenssamarbete omfattar endast geografiskt rörlig verksamhet, såsom finansiell- och annan serviceverksamhet. Organisationen har presenterat ett antal nyckelfaktorer som kan användas för att identifiera skatteparadis och skadliga förmånliga skattesystem och kommer på så vis fram till var skadlig skatt

In the last couple of years the lack of housing and homelessness has increased in Malmö. At the same time there has been a discussion about the importance of housing as a part of the aftercare related to social work. Malmö has a goal stating that people that have stayed in hospital, treatment or served a prison sentence shall be offered a drug-free housing with a personalized support. We were inte

Dagens familjer ser inte ut på samma sätt som de gjorde ”förr i tiden”, då kärnfamiljen med mamma, pappa och biologiska barn var den enda socialt accepterade familjekonstellationen. Sedan dess har stora förändringar skett hos den svenska befolkningen, som kämpat för bland annat kvinnlig frigörelse och mot patriarkala strukturer och normer. I dag erkänner det svenska rättssystemet ett flertal andraWe live in a time where one can form a family in numerous ways. A time where the nuclear family is no longer the only accepted option in our society. The movement towards women’s rights and equality, as well as the fight against patriarchal and normative structures has led to the acknowledgement of other types of families. New structures however, require new legislation. Today same-sexed marriage

This paper examines the Swedish right-wing party Christian Democrats' (Kristdemokraterna) view on privacy, as expressed in the well known and vibrant FRA-debate. FRA stands for The National Defence Radio Establishment and the debate flourished in 2008-2009, when a new law on the introduction of signals intelligence (SIGINT) was presented by the government in the Swedish parliament. This forced

FN-stadgan förhandlades fram, efter andra världskriget, i syfte att minimera risken för framtida krig och ställa all våldsanvändning under FN:s kontroll. Art 2.4 FN-stadgan förbjuder stater att bruka våld och art 51, rätten till självförsvar, är ett undantag från våldsförbudet. Tanken bakom undantaget är att garantera medlemsstaterna rätt till självförsvar om det uppstår en väpnad attack. Syftet

Social media have revolutionized the way we socialize and interact. This has led to an extreme growth in information and a number of new tools has evolved that allows us to exploit data in ways that were previously out of reach for the generalpublic. Lately, we have been able to follow the emergence of various private intelligence initiatives. One of these is Bellingcat. The purpose of this paper

This study’s main purpose is to, through discourse analysis, reveal how and to what extent New Public Management is reflected within the Swedish international development assistance and related politics during the period 2005-2015. The study also aims to explore whether there are other visible steering concepts, in order to discuss ”what comes after New Public Management”. With the help of a the

Political leaders affect the ordinary citizen´s perception of the world, making them important to study in relation to the upsurge of tension and conflict. In this specific thesis the focus is on how The Indian Express frames the discourses of the Prime Minister Narendra Modi in India concerning the relationship between Hindus, minorities and Non-Hindus. The analysis is done through an interrelate

Abstract This master thesis investigates how more value can be created by digitally visualize the saved data of GGzE (Mental Health care Eindhoven). GGzE collects a lot of data about their clients and they believe that more value can be created from it. The Dutch government, as well as the European commission, is striving for more e-health. By 2019 the Dutch government wants 80% of the ch

Rwanda’s post-genocide development is often mentioned as an exceptional success story. Thereby, education is not only one of the main drivers for development, in Rwanda it has a special significance because knowledge and expertise are the main pillars for Rwanda’s vision for the future. The past years, the Rwandan government tries to expand the education of its population and aims to decrease educ

Since the birth of the industrial revolution, there has existed a fear of becoming redundant and unemployed due to technological development. However, this has not been the case, but the last decades have instead seen the surge of income inequality. This has been linked to the growing technology bias towards skilled workers. This paper studies if the interactive effect of technological development