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Fluid intake and the risk of urothelial cell carcinomas in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Results from previous studies investigating the association between fluid intake and urothelial cell carcinomas (UCC) are inconsistent. We evaluated this association among 233,236 subjects in the European Prospective Investigation into Cancer and Nutrition (EPIC), who had adequate baseline information on water and total fluid intake. During a mean follow-up of 9.3 years, 513 first primary UCC occu

Human Retinal Development in an in situ Whole Eye Culture System.

Phenotypic characterization of human retinogenesis may be facilitated by use of the tissue culture system paradigm. Traditionally, most culture protocols involve isolation of retinal tissue and/or cells, imposing various degrees of trauma, which in many cases leads to abnormal development. In this paper, we present a novel culture technique using whole embryonic eyes to investigate whether the ret

Older Adults' Medication Use 6 Months Before and After Hip Fracture: A Population-Based Cohort Study.

OBJECTIVES: To study changes in use of fall-risk increasing drugs (FRIDs) and bone density-related medication in participants with hip fracture before and after the fracture and to analyze differences between five healthcare districts. DESIGN: Population-based cohort study. SETTING: Data retrieved from two national databases PARTICIPANTS: All 2,043 people with hip fracture aged 60 and older in a S

Protein Dynamics Studied by NMR Spin Relaxation. Conformational Transitions of a Calmodulin Mutant

Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. E140Q-Tr2C exhibits global conformational exchange on the microsecond time-scale. The populati

Return Migration from Sweden 1968-1996. A Longitudinal Analysis.

Popular Abstract in Swedish Avhandlingsarbetets främsta syfte har varit att analysera vilka drivkrafter som ligger bakom beslutet att återvandra, samt att kartlägga återvandringen från Sverige 1968-1996 avseende sammansättning och utvecklingsmönster. Analysen har bedrivits ur ett arbetsmarknadsekonomiskt perspektiv, med fokus på den långsiktiga utvecklingen av tillgång och efterfrågan på arbetskraThis book deals with return migration from Sweden in the period 1968-1996 to Chile, Germany, Greece, Iran, Poland, Turkey, United States and Yugoslavia, against the background of economic and political developments in Sweden and in the different source countries. An important question in the study regards whether return migrants deviate from other immigrants in terms of human capital characteristi

Time-Resolved Spectroscopy for Pharmaceutical Applications

The work presented in this thesis aims at improving spectroscopic techniques for analysis of pharmaceutical solids. This improvement is achieved by the combining and development of instrumentations and data evaluation tools from two research fields: the fields of near infrared spectroscopy and biomedical optics. The thesis include the construction and evaluation of different variable selection te

Relation between the rate of tumour cell proliferation and latency time in radiation associated breast cancer.

Background: Patients with possible radiation induced cancer could be used to study if the rate of tumour cell proliferation is related to latency time. Such a finding could help researcher to find time periods when other initiating risk factors operate. Methods: Seventeen women with breast cancer, with a prior history of radiation treatment towards the parts or the whole breast, exclusive of the p

"Social capital," GNP per capita, relative income, and health: an ecological study of 23 countries.

The effects of social capital, income inequality, and absolute per capita income were investigated in an ecological analysis of 23 rich and poor countries. Trust was chosen as an indicator of social capital, and GNP (gross national product) per capita and Gini index measured absolute and relative income, respectively. These independent variables were analyzed in a linear regression model with the

Histopathological classification of lung cancer: relevance of cytokeratin and TTF-1 immunophenotyping

istopathologic classification of lung carcinoma is important, as a prognostic factor and in the evaluation of treatment modalities. Although the World Health Organization classification of lung cancer is based on routine microscopy, immunohistochemistry is an important additional aspect in modern pathologic practice. This study examines whether the main histologic types of lung carcinomas are more

Predictors of falls in the elderly by location

Background and aims: In the elderly, balance and walking impairments are assumed to play an important role in causing falls. We have assessed prospectively the predictive ability of health, function and balance variables regarding falls and their location. Methods: Falls which occurred during one year in a random sample of 307 women aged 75 years and over (mean 80.8 years, response rate 74.5%) liv

Sense of Touch in Robots

This thesis discusses a number of robot touch perception systems. All these systems are self-organizing and model different aspects of human touch perception. The thesis starts out with introductions to the anatomy and the physiology of the human hand. It proceeds with an overview of the human touch perception from both a neurophysiological and a behavioural perspective. Then related robotic resea

Bra karl reder sig själv? En studie om maskulinitet och hjälpsökande

Syftet med denna studie var att undersöka mäns attityder till hjälpsökande i en svensk kontext, genom digitala enkätsvar från 195 män från varierande demografiska förhållanden. Studien utgick ifrån deltagarnas skattning av maskulinitet samt deras skattningar av självstigmatisering vid hjälpsökande hos psykolog, hos läkare och hos en vän. Resultaten visade ett positivt samband mellan skattning av mThe aim of the current study was to investigate men’s attitudes towards help seeking in a Swedish context, by means of digital self-reports from 195 men from a community sample. The study was based on the participants’ rated masculinity and their rated self-stigma of help seeking from a psychologist, a doctor, and from a friend. The results showed a positive correlation between rated masculinity a

En studie om de professionellas upplevelser av makt i arbetet med våldsutsatta kvinnor på ett skyddat boende

Domestic violence is an increasingly common problem in our society. In 2012 there were 28,400 cases reported of assault against women over 18 and almost half of these women reported having been abused by a loved one. In support of these women there is sheltered accommodation around the country, about half of Sweden's municipalities have a shelter for women and these are conducted both municipa