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Are We Creating a “World Without Us”? : Global Responsibility and Annihilism in the Works of Günther Anders, Karl Jaspers, and Hans Jonas

This essay argues that the concept of global responsibility, as articulated in the works of Karl Jaspers and Hans Jonas, was anticipated in Günther Anders' 1956 opus, Die Antiquiertheit des Menschen. By tracing the phases of Anders' negative anthropology—from his pathology of freedom to the Promethean differential andhis critique of what he considers to be an annihilistic Western stance—I examine

Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity

CONTEXT: Cardiometabolic multimorbidity (CM) is an increasing public health concern. Previous observational studies have suggested inverse associations between coffee, tea, and caffeine intake and risks of individual cardiometabolic diseases; however, their associations with CM and related biological markers are unknown.METHODS: This prospective study involved 172 315 (for caffeine analysis) and 1

Licence to Regulate: Article 114 TFEU as Choice of Legal Basis in the Digital Single Market

This chapter discusses Article 114 TFEU as the choice of legal basis in the Digital Single Market. It argues that the EU’s competence in the internal market has developed into a default option for harmonising measures in digitalisation, exacerbated by the Union’s new regulatory approach. With particular reference to the area of competition law and the recently introduced Digital Markets Act, Artic

DICHOTOMY RESULTS FOR EVENTUALLY ALWAYS HITTING TIME STATISTICS AND ALMOST SURE GROWTH OF EXTREMES

Suppose (f,X, μ) is a measure preserving dynamical system and φ: X → R a measurable function. Consider the maximum process Mn := max{X1, ,Xn}, where Xi = φ ○ fi-1 is a time series of observations on the system. Suppose that (un) is a non-decreasing sequence of real numbers, such that μ(X1 > un) → 0. For certain dynamical systems, we obtain a zero- one measure dichotomy for μ(Mn ≤ un i.o.) dependin

Economic Organizations and the Transformation Towards Degrowth

Degrowth seeks to achieve a sustainable society in the future. It implies overcoming capitalist norms and structures. Economic organizations have found little attention in degrowth scholarship. The existing literature focuses on degrowth compatibility without the wider structural and societal consideration that degrowth implies. Further, it is riddled with incoherences, such as a supposed compatib

A new mass and radius determination of the ultra-short period planet K2-106b and the fluffy planet K2-106c

Ultra-short period planets (USPs) have orbital periods of less than 1 d. Since their masses and radii can be determined to a higher precision than long-period planets, they are the preferred targets to determine the density of planets which constrains their composition. The K2-106 system is particularly interesting because it contains two planets of nearly identical masses. One is a high-density U

Sweden, Russia, and the 1617 Peace of Stolbovo

In 1617, after seven years of war between Sweden and Russia and talks facilitated by English and Dutch diplomats, the peace treaty of Stolbovo was signed. This important but little-studied document was to form the basis for relationships between Sweden and Russia for the next one hundred years, before it was replaced by the Peace of Nystad in 1721, and it had a huge influence on the lives of the p

Sugar-free antibodies--the bacterial solution to autoimmunity?

The enzyme EndoS from Streptococcus pyogenes is an immunomodulatory molecule hydrolyzing the conserved glycans in the effector part of immunoglobulin G (IgG). EndoS is remarkably specific for IgG, and hydrolysis has profound effects on IgG effector functions. EndoS pretreatment of IgG, or direct administration to animals with experimental antibody-mediated autoimmune diseases, inhibits development

Biological effects of aminoguanidine : an update

Aminoguanidine (AMG) was prepared more than 100 years ago. During the last 10 years two important effects of AMG have been discovered which have made this molecule attract a lot of interest. Firstly, AMG inhibits, in vitro and in vivo, formation of highly reactive advanced glycosylation end products (AGEs) associated with pathogenesis of secondary complications to diabetes and with cardiovascular

“We are not in this to save the polar bears!” : the link between community renewable energy development and ecological citizenship

The transition from a fossil fuel-based energy system to a renewable one has emerged as a priority for many governments. This, in turn, has facilitated a rapid increase in renewable energy investments. However, this development raises important questions about the sustainability of energy governance when it comes to access and control of energy, public participation and transparency. In this artic

Medical and assistive health technology : Meeting the needs of aging populations

Purpose of the Study: To identify policy gaps in the delivery and availability of assistive health technology (AHT) and medical devices (MD) for aging populations, particularly in low- and middle-income countries (LMICs). Design and Methods: The findings presented in this paper are the results of several narrative overviews. They provide a contextual analysis of the conclusions and evidence from W

Indian Agriculture at Crossroads

What is the situation in Indian agriculture today? What has happened to production and distribution of land since independence? What has happened after the liberalisation of the Indian economy in the 1990s?